Baxter Presents Real-World Data at American Society of Health System Pharmacists Meeting Demonstrating Smart Infusion Pump Electronic Medical Record (EMR) Integration May Improve Patient Safety and Nursing Bedside Productivity

• Data shared in collaboration with The University of Texas Medical Branch, representing an analysis of more than one million intravenous (IV) infusions using Baxter's Spectrum IQ large volume infusion pumps (LVP)
• Evaluation of pre- and post-smart pump EMR integration data showed a reduction in patient safety alerts, time spent to program an infusion and to resolve a pump alert
• Findings underscore the potential role of connected infusion therapy in supporting patient safety, addressing clinician burnout and compliance

Baxter International Inc. (NYSE:BAX), an innovative leader in infusion therapies and technologies, today announced data in collaboration with The University of Texas Medical Branch (UTMB Health) demonstrating the positive impact of smart infusion pump integration with hospital electronic medical records (EMRs) on patient safety, clinicians' bedside productivity and programming compliance. The analyses of more than one million infusions on Baxter's Spectrum IQ large volume infusion pumps (LVP) at UTMB were presented at the American Society of Health-System Pharmacists (ASHP) 2025 Midyear Clinical Meeting, held Dec. 7 – Dec. 10, 2025.

"Health systems face mounting challenges, from resource shortages to staff fatigue, yet remain committed to delivering the highest standards of care," said Jay Ehrlich, MD, vice president of global patient safety and clinical research at Baxter. "Baxter is proud to provide technologies that help address these priorities and foster ongoing quality improvement initiatives to help advance patient safety and address cognitive overload for clinicians. The findings presented at ASHP, developed in collaboration with the University of Texas Medical Branch, reinforce the potential broad impact of, and opportunities associated with, smart infusion pump EMR integration."

Intravenous (IV) medication errors remain a common yet often preventable cause of patient harm.^{i, ii} Smart infusion pump capabilities like auto-programming, which is enabled through EMR integration, and dose-error reduction systems (DERS), which help prevent medication errors by checking programmed doses against preset drug-specific soft and hard limits, help support safer medication administration and offer the opportunity to help minimize manual tasks and reduce cognitive burden for nurses at the bedside.^{iii, iv}

The information presented at ASHP leverages retrospectively collected data of 1.3 million infusions using Baxter's Spectrum IQ LVP at six UTMB hospitals over a three-year period. The data was analyzed and compared based on EMR integration status, care area and infusion programming type (e.g., manual vs. auto-programming). In addition to improved DERS and auto-programming compliance after EMR integration, key findings include:

• Patient Safety: Following EMR integration, all evaluated safety alerts for infusions decreased in frequency, with DERS hard limit alerts decreasing by 50.3%, soft limit alerts by 30.4% and single step rate change (SSRC) alerts -- a safety feature unique to Baxter's infusion pump portfolio -- by 38.1%, implying that more programmed doses were within the drug library limits.^v These alert types were also substantially less frequent when comparing auto-programmed to manually programmed infusions, likely due to the avoidance of manual programming errors. The data also suggests that drug library optimization with use of auto-programming resulted in fewer required interventions.

• Clinician Productivity: EMR integration-enabled auto-programming utilizes streamlined sequential bar code scanning compared to manual keypad entry for manually programmed infusions. Post EMR-integration, the use of auto-programming required fewer steps than manual programming and also reduced median time to program an infusion from 10 seconds to four seconds. In cases where the pump issued a programming alert in the post-integration phase, the average time to address soft limit alerts decreased by nearly 50%, while single step rate change alert resolution time dropped by 55%.

"Integrating smart infusion pumps with our EMR is more than a technology upgrade—it's a commitment to safer, more efficient care at the bedside. This collaboration helps our clinicians spend less time troubleshooting and more time focusing on patients," said Juanita Norton, PhD, MBA, MSN, CPHQ, RN-BC, CPN, CLSSBB, program manager, quality improvement, The University of Texas Medical Branch.

These findings help address two critical priorities for health systems: reducing preventable safety alerts and alleviating clinician workload. By demonstrating a measurable reduction in safety limit alerts and workflow improvements, this analysis underscores how smart pump EMR integration, with DERS and auto-programming, may help health systems deliver safer, more efficient care. Learn more about the data presented at ASHP here.

About Baxter

At Baxter, we are everywhere healthcare happens – and everywhere it is going, with essential solutions in the hospital, physician's office and other sites of care. For nearly a century, our customers have counted on us as a vital and trusted partner. And every day, millions of patients and healthcare providers rely on our unmatched portfolio of connected solutions, medical devices, and advanced injectable technologies. Approximately 38,000 Baxter team members live our enduring Mission: to Save and Sustain Lives. Together, we are redefining how care is delivered to make a greater impact today, tomorrow, and beyond. To learn more, visit www.baxter.com and follow us on X, LinkedIn and Facebook.

About The University of Texas Medical Branch (UTMB)

The first academic health center in Texas opened its doors in 1891 and today has four campuses, five health sciences schools, seven institutes for advanced study, a research enterprise that includes one of only two national laboratories dedicated to the safe study of infectious threats to human health, a Level 1 Trauma Center and a health system offering a full range of primary and specialized medical services throughout the Texas Gulf Coast region. UTMB is an institution in The University of Texas System and a member of the Texas Medical Center.

Rx Only. For safe and proper use of this device, refer to the full Instructions for Use.

INDICATIONS

The Spectrum IQ Infusion System with Dose IQ Safety Software is intended to be used for the controlled administration of fluids. These may include pharmaceutical drugs, blood, and blood products. The intended routes of administration consist of the following clinically accepted routes: IV, arterial, subcutaneous, or epidural. The Spectrum IQ Infusion System with Dose IQ Safety Software is intended to be used in conjunction with legally marketed and compatible IV administration sets and medications provided by the user. The Spectrum IQ Infusion System with Dose IQ Safety Software is suitable for a variety of patient care environments such as, but not limited to, hospitals and outpatient care areas. The Spectrum IQ Infusion System with Dose IQ Safety Software is intended to reduce operator interaction through guided programming, including a way to automate the programming of infusion parameters and documentation of infusion therapies. This automation is intended to reduce pump programming errors. The Spectrum IQ Infusion System with Dose IQ Safety Software is intended to be used by trained healthcare professionals.

This release includes forward-looking statements concerning potential benefits associated with Spectrum IQ LVP. The statements are based on assumptions about many important factors, including the following, which could cause actual results to differ materially from those in the forward-looking statements: demand and market acceptance for, and competitive pressures (including pricing) related to, new and existing products; product development risks; inability to create additional production capacity in a timely manner or the occurrence of other manufacturing or supply difficulties (including as a result of natural disasters, public health crises and epidemics/pandemics, war, terrorism, regulatory actions or otherwise); satisfaction of regulatory and other requirements; actions of regulatory bodies and other governmental authorities; product quality, manufacturing or supply, or patient safety issues; changes in law and regulations; and other risks identified in Baxter's most recent filing on Form 10-K and Form 10-Q and other SEC filings, all of which are available on Baxter's website. Baxter does not undertake to update its forward-looking statements.

Baxter and Spectrum IQ are registered trademarks of Baxter International Inc.

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