• Live Feeds
    • Press Releases
    • Insider Trading
    • FDA Approvals
    • Analyst Ratings
    • Insider Trading
    • SEC filings
    • Market insights
  • Analyst Ratings
  • Alerts
  • Subscriptions
  • Settings
  • RSS Feeds
Quantisnow Logo
  • Live Feeds
    • Press Releases
    • Insider Trading
    • FDA Approvals
    • Analyst Ratings
    • Insider Trading
    • SEC filings
    • Market insights
  • Analyst Ratings
  • Alerts
  • Subscriptions
  • Settings
  • RSS Feeds
PublishGo to App
    Quantisnow Logo

    © 2026 quantisnow.com
    Democratizing insights since 2022

    Services
    Live news feedsRSS FeedsAlertsPublish with Us
    Company
    AboutQuantisnow PlusContactJobsAI superconnector for talent & startupsNEWLLM Arena
    Legal
    Terms of usePrivacy policyCookie policy

    Direxion Launches mRNA ETF (MSGR)

    12/9/21 8:41:00 AM ET
    $ALNY
    $ARWR
    $BGNE
    $BNTX
    Biotechnology: Pharmaceutical Preparations
    Health Care
    Biotechnology: Pharmaceutical Preparations
    Health Care
    Get the next $ALNY alert in real time by email

    NEW YORK, Dec. 9, 2021 /PRNewswire/ -- Direxion announced today the launch of the Direxion mRNA ETF (Ticker: MSGR). MSGR invests in companies believed to be at the forefront of the development and application of messenger RNA technology.

    The MSGR ETF seeks investment results, before fees and expenses, of the BITA Messenger RNA Technology Index. The BITA Messenger RNA Technology Index provides exposure to the performance of companies, publicly listed in the United States, Canada and Europe, that are leading the development and application of mRNA technology. mRNA is a single-stranded ribonucleic acid molecule that is complementary to one of the DNA strands of a gene. mRNA plays a vital role in protein synthesis in the human body, and mRNA technologies leverage this vital role to enable targeted cells to produce proteins that enable the body to fight, or prevent, a given disease.

    "For years, messenger RNA (mRNA) technologies struggled to gain acceptance. The COVID-19 pandemic changed all of that, thanks to the highly effective vaccines developed using mRNA to combat the novel coronavirus and its emerging variants," said David Mazza, Managing Director, Head of Product at Direxion. "MSGR captures companies specifically involved with mRNA technologies that are believed to be at the forefront of fighting the battle against COVID, while also highlighting mRNA's application to other viruses and diseases, including HIV and Lyme disease."

    Investors seeking to gain exposure to mRNA stocks, and the mRNA sector, can access companies such as Moderna, Inc. (MRNA), BioNTech SE (BNTX), Vertex Pharmaceuticals Inc (VRTX) and others through this mRNA ETF ($MSGR). For additional nanotech stocks, see the table below.

    As of November 19, 2021, the 24 constituents had a median total market capitalization of $2 billion, total market capitalizations ranging from $41 million to $107 billion, and were concentrated in the healthcare sector. Top ten index holdings are as follows:

    mRNA ETF ( Ticker: MSGR) Index Holdings

    Name

    Ticker

    GICS Sub-Industry

    Market

    Cap ($B)

    Weight

    (%)

    BioNTech SE

    BNTX

    Biotechnology

    85.30

    9.41

    Dicerna Pharmaceuticals Inc

    DRNA

    Pharmaceuticals

    2.96

    8.22

    Vertex Pharmaceuticals Inc

    VRTX

    Pharmaceuticals

    47.53

    7.07

    Moderna Inc

    MRNA

    Biotechnology & Pharmaceuticals

    142.89

    7.04

    BeiGene Ltd

    BGNE

    Biotechnology

    32.45

    6.64

    Alnylam Pharmaceuticals Inc

    ALNY

    Pharmaceuticals

    21.98

    6.50

    Gritstone bio Inc

    GRTS

    Biotechnology

    0.90

    5.34

    Arrowhead Pharmaceuticals Inc

    ARWR

    Pharmaceuticals

    7.32

    4.90

    Maravai LifeSciences Holdings Inc

    MRVI

    Biotechnology

    11.84

    4.65

    CureVac NV

    CVAC

    Biotechnology

    9.00

    4.54

    Source: Source: Bloomberg Finance, L.P., BITA, as of 11.30.2021.

    About Direxion:

    Direxion equips traders with ways to execute short-term, tactical trades and investors with strategic exposures, and thematic strategies, focused on emerging trends. Founded in 1997, the company has approximately $25.1 billion in assets under management as of September 30, 2021. For more information, please visit www.direxion.com.   

    ###

    For more information on all Direxion Shares daily leveraged ETFs, go to direxion.com, or call us at 866.476.7523.

    An investor should carefully consider a Fund's investment objective, risks, charges, and expenses before investing. A Fund's prospectus and summary prospectus contain this and other information about the Direxion Shares. To obtain a Fund's prospectus and summary prospectus call 866-716-0735 or visit our website at direxion.com. A Fund's prospectus and summary prospectus should be read carefully before investing.

    Direxion Shares Risks –  Investing involves risk including possible loss of principal. There is no guarantee the investment strategy will be successful. mRNA technology is a novel technology and the development of products or therapies based on mRNA technology has substantial clinical development and regulatory risks. mRNA technologies may also provide ineffective or may produce adverse effects. Negative perception of the efficacy, safety, or tolerability of such mRNA-based products or therapies could adversely affect a company and the general acceptance of mRNA technologies. Certain mRNA-based vaccines only have received Emergency Use Authorization from the U.S. Food and Drug Administration and other provisional, interim or conditional authorizations from regulatory authorities outside the United States, and there is no guarantee that such vaccines will receive full approval in the future.

    Additional risks of the Fund include, but are not limited to, Non-Diversification Risk, Index Correlation/Tracking Risk, Index Strategy Risk, Biotechnology Industry Risk, Healthcare Sector Risk, Natural Disaster/Epidemic and Market Disruption Risk, Foreign Securities Risk and risks associated with the market capitalizations and sectors of the securities in which the Fund may invest. Please see the summary and full prospectuses for a more complete description of these and other risks of the Fund.

    Distributor: Foreside Fund Services, LLC.

    CONTACT:   

    James Doyle



    JConnelly



    973.850.7308



    [email protected]

     

    Cision View original content:https://www.prnewswire.com/news-releases/direxion-launches-mrna-etf-msgr-301441238.html

    SOURCE Direxion

    Get the next $ALNY alert in real time by email

    Crush Q1 2026 with the Best AI Superconnector

    Stay ahead of the competition with Standout.work - your AI-powered talent-to-startup matching platform.

    AI-Powered Inbox
    Context-aware email replies
    Strategic Decision Support
    Get Started with Standout.work

    Recent Analyst Ratings for
    $ALNY
    $ARWR
    $BGNE
    $BNTX

    CompanyDatePrice TargetRatingAnalyst
    Vertex Pharmaceuticals Incorporated
    $VRTX
    1/12/2026Mkt Perform → Outperform
    Bernstein
    Vertex Pharmaceuticals Incorporated
    $VRTX
    1/7/2026$535.00Buy
    UBS
    Moderna Inc.
    $MRNA
    1/7/2026$34.00Neutral
    UBS
    Alnylam Pharmaceuticals Inc.
    $ALNY
    1/7/2026$500.00Outperform
    Oppenheimer
    Vertex Pharmaceuticals Incorporated
    $VRTX
    1/6/2026$548.00Peer Perform → Outperform
    Wolfe Research
    Moderna Inc.
    $MRNA
    12/12/2025$30.00Hold
    Jefferies
    Vertex Pharmaceuticals Incorporated
    $VRTX
    12/3/2025$516.00Equal-Weight → Overweight
    Morgan Stanley
    Vertex Pharmaceuticals Incorporated
    $VRTX
    11/13/2025$495.00Sector Outperform
    Scotiabank
    More analyst ratings

    $ALNY
    $ARWR
    $BGNE
    $BNTX
    SEC Filings

    View All

    Arrowhead Pharmaceuticals Inc. filed SEC Form 8-K: Entry into a Material Definitive Agreement, Creation of a Direct Financial Obligation

    8-K - ARROWHEAD PHARMACEUTICALS, INC. (0000879407) (Filer)

    1/12/26 5:00:35 PM ET
    $ARWR
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Alnylam Pharmaceuticals Inc. filed SEC Form 8-K: Results of Operations and Financial Condition, Financial Statements and Exhibits

    8-K - ALNYLAM PHARMACEUTICALS, INC. (0001178670) (Filer)

    1/12/26 7:30:20 AM ET
    $ALNY
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Moderna Inc. filed SEC Form 8-K: Results of Operations and Financial Condition, Regulation FD Disclosure, Financial Statements and Exhibits

    8-K - Moderna, Inc. (0001682852) (Filer)

    1/12/26 7:01:10 AM ET
    $MRNA
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    $ALNY
    $ARWR
    $BGNE
    $BNTX
    FDA approvals

    Live FDA approvals issued by the Food and Drug Administration and FDA breaking news

    View All

    January 30, 2025 - FDA Approves Novel Non-Opioid Treatment for Moderate to Severe Acute Pain

    For Immediate Release: January 30, 2025 Today, the U.S. Food and Drug Administration approved Journavx (suzetrigine) 50 milligram oral tablets, a first-in-class non-opioid analgesic, to treat moderate to severe acute pain in adults. Journavx reduces pain by targeting a pain-signaling pathway involving sodium channels in the peripheral nervous system, before pain signals reach the brain.  Journavx is the first dr

    1/30/25 5:46:14 PM ET
    $VRTX
    Biotechnology: Pharmaceutical Preparations
    Health Care

    FDA Approval for GIVLAARI issued to ALNYLAM PHARMS INC

    Submission status for ALNYLAM PHARMS INC's drug GIVLAARI (SUPPL-7) with active ingredient GIVOSIRAN SODIUM has changed to 'Approval' on 04/29/2024. Application Category: NDA, Application Number: 212194, Application Classification: Labeling

    4/30/24 1:44:03 PM ET
    $ALNY
    Biotechnology: Pharmaceutical Preparations
    Health Care

    December 8, 2023 - FDA Approves First Gene Therapies to Treat Patients with Sickle Cell Disease

    For Immediate Release: December 08, 2023 Today, the U.S. Food and Drug Administration approved two milestone treatments, Casgevy and Lyfgenia, representing the first cell-based gene therapies for the treatment of sickle cell disease (SCD) in patients 12 years and older. Additionally, one of these therapies, Casgevy, is the first FDA-approved treatment to utilize a type of novel genome editing technology, signali

    12/8/23 11:12:21 AM ET
    $BLUE
    $VRTX
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care
    Biotechnology: Pharmaceutical Preparations

    $ALNY
    $ARWR
    $BGNE
    $BNTX
    Analyst Ratings

    Analyst ratings in real time. Analyst ratings have a very high impact on the underlying stock. See them live in this feed.

    View All

    Vertex Pharma upgraded by Bernstein

    Bernstein upgraded Vertex Pharma from Mkt Perform to Outperform

    1/12/26 7:48:54 AM ET
    $VRTX
    Biotechnology: Pharmaceutical Preparations
    Health Care

    UBS resumed coverage on Vertex Pharma with a new price target

    UBS resumed coverage of Vertex Pharma with a rating of Buy and set a new price target of $535.00

    1/7/26 9:39:59 AM ET
    $VRTX
    Biotechnology: Pharmaceutical Preparations
    Health Care

    UBS resumed coverage on Moderna with a new price target

    UBS resumed coverage of Moderna with a rating of Neutral and set a new price target of $34.00

    1/7/26 9:12:19 AM ET
    $MRNA
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    $ALNY
    $ARWR
    $BGNE
    $BNTX
    Press Releases

    Fastest customizable press release news feed in the world

    View All

    BioNTech Provides Strategic Business Update and Outlines 2026 Areas of Focus at 44th Annual J.P. Morgan Healthcare Conference

    2026 poised to be a catalyst-rich year for BioNTech with continued late-stage pipeline progress with candidates across immunomodulators, antibody-drug conjugates and mRNA immunotherapiesExpected 2026 oncology milestones include seven late-stage data readouts and to have 15 Phase 3 clinical trials ongoing by year endAdditional late-stage trial readouts through 2030+ set to create multiple launch opportunities across tumor types, building BioNTech into a multi-product oncology company Financial strength with €17.2 billion in cash and cash equivalents plus security investments1, COVID-19 vaccine revenue stream, disciplined R&D spend, and strategic partnerships will continue to enable sustainabl

    1/12/26 6:45:00 AM ET
    $BNTX
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    Vertex Provides Pipeline and Business Updates in Advance of Upcoming Investor Meetings

    Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX) today announced business and program updates ahead of upcoming investor meetings in January, including the company's scheduled webcast from the 44th annual J.P. Morgan Healthcare Conference on Monday, January 12, 2026, at 5:15 p.m. ET/2:15 p.m. PT. "2025 was a year of strong commercial execution and rapid R&D progress, setting up the company for continued growth and many important milestones in 2026," said Reshma Kewalramani, M.D., Chief Executive Officer and President of Vertex. "Building on this momentum, we are focused on expanding our commercial reach in multiple disease areas; advancing the emerging renal franchise, including the pote

    1/11/26 5:00:00 PM ET
    $VRTX
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Alnylam Launches "Alnylam 2030" Strategy to Drive Next Era of Growth and Patient Impact

    − Full Year 2025 Preliminary* Net Product Revenues of $2,987 Million (81% Growth vs. 2024), Driven Primarily by Preliminary* Total TTR Revenues of $2,487 Million (103% Growth vs. 2024) – − Company Provides 2026 Combined Net Product Revenue Guidance of $4,900 Million to $5,300 Million, Driven Primarily by Total TTR Net Product Revenue Guidance of $4,400 Million to $4,700 Million – – 2026 Pipeline Goals Focused on Continued Advancement of Numerous Multi-Billion-Dollar Opportunities – Alnylam Pharmaceuticals, Inc. (NASDAQ:ALNY), the leading RNAi therapeutics company, today announced its new five-year strategy, "Alnylam 2030," focused on scaling the Company's operations through achieving

    1/11/26 5:00:00 PM ET
    $ALNY
    Biotechnology: Pharmaceutical Preparations
    Health Care

    $ALNY
    $ARWR
    $BGNE
    $BNTX
    Insider Trading

    Insider transactions reveal critical sentiment about the company from key stakeholders. See them live in this feed.

    View All

    EVP, Chief Reg. & Quality Off. Tatsis Ourania sold $2,137,455 worth of shares (4,500 units at $474.99), decreasing direct ownership by 10% to 42,293 units (SEC Form 4)

    4 - VERTEX PHARMACEUTICALS INC / MA (0000875320) (Issuer)

    1/9/26 4:05:25 PM ET
    $VRTX
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Chief Medical Officer Hamilton James C was granted 75,000 shares, increasing direct ownership by 44% to 246,958 units (SEC Form 4)

    4 - ARROWHEAD PHARMACEUTICALS, INC. (0000879407) (Issuer)

    1/8/26 6:45:55 PM ET
    $ARWR
    Biotechnology: Pharmaceutical Preparations
    Health Care

    COO O'Brien Patrick gifted 2,500 shares and was granted 75,000 shares, increasing direct ownership by 15% to 547,408 units (SEC Form 4)

    4 - ARROWHEAD PHARMACEUTICALS, INC. (0000879407) (Issuer)

    1/8/26 6:45:43 PM ET
    $ARWR
    Biotechnology: Pharmaceutical Preparations
    Health Care

    $ALNY
    $ARWR
    $BGNE
    $BNTX
    Insider Purchases

    Insider purchases reveal critical bullish sentiment about the company from key stakeholders. See them live in this feed.

    View All

    Director Lucier Gregory T bought $368,544 worth of shares (100,000 units at $3.69), increasing direct ownership by 181% to 155,123 units (SEC Form 4)

    4 - MARAVAI LIFESCIENCES HOLDINGS, INC. (0001823239) (Issuer)

    12/9/25 4:36:29 PM ET
    $MRVI
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Chief Executive Officer Brust Bernd bought $702,689 worth of shares (216,212 units at $3.25) (SEC Form 4)

    4 - MARAVAI LIFESCIENCES HOLDINGS, INC. (0001823239) (Issuer)

    11/17/25 4:48:14 PM ET
    $MRVI
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Chief Executive Officer Brust Bernd bought $809,010 worth of shares (250,559 units at $3.23) (SEC Form 4)

    4 - MARAVAI LIFESCIENCES HOLDINGS, INC. (0001823239) (Issuer)

    11/13/25 5:27:45 PM ET
    $MRVI
    Biotechnology: Pharmaceutical Preparations
    Health Care

    $ALNY
    $ARWR
    $BGNE
    $BNTX
    Financials

    Live finance-specific insights

    View All

    Annual Changes to the Nasdaq-100 Index®

    NEW YORK, Dec. 12, 2025 (GLOBE NEWSWIRE) -- Nasdaq (NASDAQ:NDAQ) today announced the results of the annual reconstitution of the Nasdaq-100 Index® (NDX®), which will become effective prior to market open on Monday, December 22, 2025. The following six companies will be added to the Index: Alnylam Pharmaceuticals, Inc. (NASDAQ:ALNY), Ferrovial SE (NASDAQ:FER), Insmed Incorporated (NASDAQ:INSM), Monolithic Power Systems, Inc. (NASDAQ:MPWR), Seagate Technology Holdings plc (NASDAQ:STX), Western Digital Corp. (NASDAQ:WDC). The Nasdaq-100 Index is a globally recognized index that tracks the performance of 100 of the largest non-financial companies listed on the Nasdaq Stock Market® encompassi

    12/12/25 8:00:00 PM ET
    $ALNY
    $BIIB
    $CDW
    Biotechnology: Pharmaceutical Preparations
    Health Care
    Biotechnology: Biological Products (No Diagnostic Substances)
    Retail: Computer Software & Peripheral Equipment

    Arrowhead Pharmaceuticals Reports 2025 Fiscal Year-End Results

    - Conference Call and Webcast Today, November 25, 2025, at 4:30 p.m. ET Arrowhead Pharmaceuticals, Inc. (NASDAQ:ARWR) today announced financial results for its 2025 fiscal year ended September 30, 2025. The Company is hosting a conference call today, November 25, 2025, at 4:30 p.m. ET to discuss the results. "The recent FDA approval of REDEMPLO, indicated as an adjunct to diet to reduce triglycerides in adults with familial chylomicronemia syndrome (FCS), is a transformational milestone for Arrowhead. REDEMPLO is the first and only FDA-approved siRNA medicine for people living with FCS and represents the first FDA-approval for a medicine leveraging Arrowhead's proprietary and differentiat

    11/25/25 4:00:00 PM ET
    $ARWR
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Arrowhead Pharmaceuticals Announces FDA Approval of REDEMPLO® (plozasiran) to Reduce Triglycerides in Adults with Familial Chylomicronemia Syndrome (FCS)

    - REDEMPLO is the first and only FDA-approved medicine to be studied in patients with genetically confirmed and clinically diagnosed FCS - People living with FCS have extremely high triglyceride levels and a substantially higher risk of acute pancreatitis and related long-term complications, often resulting in a reduced quality of life - The FDA approval is based on positive results from the Phase 3 PALISADE study where REDEMPLO significantly reduced triglycerides from baseline and lowered the numerical incidence of acute pancreatitis compared to placebo - Arrowhead will host a conference call and webcast today at 1:30 p.m. ET Arrowhead Pharmaceuticals, Inc. (NASDAQ:ARWR) today anno

    11/18/25 11:52:00 AM ET
    $ARWR
    Biotechnology: Pharmaceutical Preparations
    Health Care

    $ALNY
    $ARWR
    $BGNE
    $BNTX
    Leadership Updates

    Live Leadership Updates

    View All

    Alnylam Pharmaceuticals Announces Changes to Board of Directors

    – Mike Bonney and Carolyn Bertozzi to Depart; Company Appoints Stuart Arbuckle as New Independent Director – Alnylam Pharmaceuticals, Inc. (NASDAQ:ALNY), the leading RNAi therapeutics company, today announced changes to its Board of Directors, including the departure of two directors and the appointment of a new independent director. Mike Bonney and Carolyn Bertozzi, Ph.D., who have served in key roles on Alnylam's Board, stepped down effective December 2, 2025. Mr. Bonney joined our Board in 2014 and served as Board Chair from December 2015 to August 2021 and as Executive Chair from August 2021 to January 2023. He helped to guide the company through major milestones and significant growt

    12/3/25 8:00:00 AM ET
    $ALNY
    Biotechnology: Pharmaceutical Preparations
    Health Care

    BioNTech to Host Innovation Series R&D Day on November 11, 2025

    MAINZ, Germany, October 28, 2025 (GLOBE NEWSWIRE) -- BioNTech SE (NASDAQ:BNTX, "BioNTech" or "the Company")), will host an edition of the Company's Innovation Series R&D Day at 09:00 a.m. Eastern Standard Time (3:00 p.m. CET) on Tuesday, November 11, 2025 in New York City, U.S. On the day, members of BioNTech's leadership team will provide an overview of the Company's strategy and clinical progress across its pipeline. Investors, analysts and the interested public are invited to join the event online via this link. A replay of the webcast will be available shortly after the conclusion of the event and archived on the Company's website for one year following the call. The public may also

    10/28/25 7:45:00 AM ET
    $BNTX
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    Alnylam Pharmaceuticals joins Alliance for Genomic Discovery, expanding diverse clinical genomic dataset to drive precision medicine

    Alnylam, a leader in RNA interference (RNAi) therapeutics, will utilize the AGD dataset to inform development of 'gene silencing' medicines Members leverage AI-powered dataset to accelerate pharma R&D, and ensure that disease-impacting discoveries benefit all people SAN DIEGO, Sept. 18, 2025 /PRNewswire/ -- Illumina, Inc. (NASDAQ:ILMN), and Nashville Biosciences, LLC (NashBio), today announced Alnylam Pharmaceuticals, Inc. (NASDAQ:ALNY) (Alnylam) as a member of the Alliance for Genomic Discovery (AGD). Alnylam, a pioneer in RNA interference (RNAi) therapeutics, will utilize the AGD clinical genomic database to derive real-world insights and accelerate drug target discovery.

    9/18/25 9:15:00 AM ET
    $ALNY
    $ILMN
    Biotechnology: Pharmaceutical Preparations
    Health Care
    Medical Specialities

    $ALNY
    $ARWR
    $BGNE
    $BNTX
    Large Ownership Changes

    This live feed shows all institutional transactions in real time.

    View All

    Amendment: SEC Form SC 13D/A filed by BeiGene Ltd.

    SC 13D/A - BeiGene, Ltd. (0001651308) (Subject)

    12/10/24 9:30:34 PM ET
    $BGNE
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Amendment: SEC Form SC 13D/A filed by BeiGene Ltd.

    SC 13D/A - BeiGene, Ltd. (0001651308) (Subject)

    12/4/24 4:05:33 PM ET
    $BGNE
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Amendment: SEC Form SC 13G/A filed by Maravai LifeSciences Holdings Inc.

    SC 13G/A - MARAVAI LIFESCIENCES HOLDINGS, INC. (0001823239) (Subject)

    11/14/24 7:49:19 PM ET
    $MRVI
    Biotechnology: Pharmaceutical Preparations
    Health Care