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    SEC Form 4 filed by Co-Chief Executive Officer Duggan Robert W

    1/6/25 7:49:10 PM ET
    $SMMT
    Biotechnology: Pharmaceutical Preparations
    Health Care
    Get the next $SMMT alert in real time by email
    SEC FORM 4 SEC Form 4
    FORM 4 UNITED STATES SECURITIES AND EXCHANGE COMMISSION
    Washington, D.C. 20549

    STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

    Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
    or Section 30(h) of the Investment Company Act of 1940
    OMB APPROVAL
    OMB Number: 3235-0287
    Estimated average burden
    hours per response: 0.5
      
    Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
      
    Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.
    1. Name and Address of Reporting Person*
    DUGGAN ROBERT W

    (Last) (First) (Middle)
    C/O SUMMIT THERAPEUTICS INC.
    601 BRICKELL KEY DRIVE SUITE 1000

    (Street)
    MIAMI FL 33131

    (City) (State) (Zip)
    2. Issuer Name and Ticker or Trading Symbol
    Summit Therapeutics Inc. [ SMMT ]
    5. Relationship of Reporting Person(s) to Issuer
    (Check all applicable)
    X Director X 10% Owner
    X Officer (give title below) Other (specify below)
    Co-Chief Executive Officer
    3. Date of Earliest Transaction (Month/Day/Year)
    01/02/2025
    4. If Amendment, Date of Original Filed (Month/Day/Year)
    6. Individual or Joint/Group Filing (Check Applicable Line)
    X Form filed by One Reporting Person
    Form filed by More than One Reporting Person
    Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
    1. Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
    Code V Amount (A) or (D) Price
    Common Stock 551,695,096 D
    Common Stock 31,000(1)(2) I By Spouse
    Common Stock 10,199,776(1)(2) I By the Shaun Zanganeh Irrevocable Trust, with the Spouse of Reporting Person as Trustee
    Common Stock 25,457,666(1)(2) I By the Mahkam Zanganeh Revocable Trust, with the Spouse of Reporting Person as Trustee
    Common Stock 50,000(1)(2) I Immediate family member of Spouse
    Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
    (e.g., puts, calls, warrants, options, convertible securities)
    1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 6. Date Exercisable and Expiration Date (Month/Day/Year) 7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
    Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
    Stock Option (right to buy) $18.35 01/02/2025 A 10,724 (3) 01/02/2035 Common Stock 10,724 $9.18(4) 10,724 D
    Stock Option (right to buy) $3.71 (5) 11/11/2030 Common Stock 203,323 203,323(1)(2) I By Spouse
    Stock Option (right to buy) $4.4 (6) 11/22/2030 Common Stock 2,400,000 2,400,000(1)(2) I By Spouse
    Stock Option (right to buy) $4.75 (7) 12/15/2031 Common Stock 15,000 15,000(1)(2) I By Spouse
    Stock Option (right to buy) $1.68 (8) 10/13/2033 Common Stock 11,988,198 11,988,198(1)(2) I By Spouse
    Performance Stock Option (right to buy) $1.06 (9) 06/28/2032 Common Stock 260,000 260,000(1)(2) I By Spouse
    Performance Stock Option (right to buy) $1.29 (10) 09/09/2032 Common Stock 100,000 100,000(1)(2) I By Spouse
    Performance Stock Option (right to buy) $1.68 (11) 10/13/2033 Common Stock 2,397,640 2,397,640(1)(2) I By Spouse
    Explanation of Responses:
    1. The Reporting Person acquired beneficial ownership of these securities upon his marriage to the beneficial owner of the securities on December 18, 2024.
    2. The Reporting Person disclaims beneficial ownership of these securities, except to the extent of his pecuniary interest therein, if any, and the inclusion of these securities in this report shall not be deemed an admission of beneficial ownership of all of the reported securities for purposes of Section 16 or for any other purpose.
    3. The option was granted on January 2, 2025. The shares underlying the option shall vest in four quarterly installments on March 31, June 30, September 30 and December 31 following election, subject to the reporting person remaining as a non-salaried director on each such vesting date.
    4. The option was issued to the reporting person pursuant to the Director Retainer Option Election Plan of issuer in lieu of retainer fees of $98,400.
    5. The option was granted to the Reporting Person's spouse on November 11, 2020 pursuant to the Issuer's Stock Incentive Plan, and are fully vested.
    6. The option was granted to the Reporting Person's spouse on November 22, 2020 pursuant to the Issuer's Stock Incentive Plan. The shares underlying the option are fully vested.
    7. The option was granted to the Reporting Person's spouse on December 15, 2021. The shares underlying the option are fully vested.
    8. The option was granted to the Reporting Person's spouse on October 13, 2023. The shares underlying the option shall vest in four equal annual installments, with the first such installment occurring on October 13, 2024. Note this does not include an additional 11,988,198 options which were granted to the Reporting Person's spouse on October 13, 2023 and are subject to the satisfaction of performance conditions based on market capitalization and revenue targets.
    9. These performance-based stock options vested on August 23, 2024, upon the attainment of the satisfaction of certain financial performance objectives. Note this does not include an additional 1,040,000 shares underlying options which were granted to the Reporting Person's spouse on June 28, 2022, that remain subject to the satisfaction of performance conditions.
    10. These performance-based stock options vested on August 23, 2024, upon the attainment of the satisfaction of certain financial performance objectives. Note this does not include an additional 400,000 shares underlying options which were granted to the Reporting Person's spouse on September 9, 2022 that remain subject to the satisfaction of performance conditions.
    11. These performance-based stock options vested on August 23, 2024, upon the attainment of the satisfaction of certain financial performance objectives. Note this does not include an additional 9,590,558 shares underlying options which were granted to the Reporting Person's spouse on October 13, 2023 that remain subject to the satisfaction of performance conditions.
    Remarks:
    /s/ Robert W. Duggan 01/06/2025
    ** Signature of Reporting Person Date
    Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
    * If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
    ** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
    Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
    Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.