SEC Form SC 13G/A filed by Aldeyra Therapeutics, Inc. (Amendment)

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C.  20549

_____________________

SCHEDULE 13G

(Rule 13d-102)

INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT

TO RULES 13d-1(b),(c) AND (d) AND AMENDMENTS THERETO FILED

PURSUANT TO RULE 13d-2(b)

(Amendment No. 2)¹

Check the appropriate box to designate the rule pursuant to which this Schedule is Filed:

[   ] Rule 13d-1(b)

[   ] Rule 13d-1(c)

[X] Rule 13d-1(d)

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¹The remainder of this cover page shall be filled out for a reporting person's initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter disclosures provided in a prior cover page.  The information required on the remainder of this cover page shall not be deemed to be "filed" for the purpose of Section 18 of the Securities Exchange Act of 1934 or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act.

CUSIP No. 01438T106

1)	Name of Reporting Person I.R.S. Identification No. of Above Person (Entities Only) (Voluntary)   Domain Partners VI, L.P.
2)	Check the Appropriate Box if a Member of a Group			(a) [X] (b) [   ]
3)	SEC Use Only
4)	Citizenship or Place of Organization			Delaware
Number of Shares Beneficially Owned by Each Reporting Person With		5)	Sole Voting Power	-0-
		6)	Shared Voting Power	-0-
		7)	Sole Dispositive Power	-0-
		8)	Shared Dispositive Power	-0-
9)	Aggregate Amount Beneficially Owned by Each Reporting Person			-0-
10)	Check if the Aggregate Amount in Row (9) Excludes Certain Shares			[   ]
11)	Percent of Class Represented by Amount in Row (9)			-0-
12)	Type of Reporting Person			PN

CUSIP No. 01438T106

1)	Name of Reporting Person I.R.S. Identification No. of Above Person (Entities Only) (Voluntary)   DP VI Associates, L.P.
2)	Check the Appropriate Box if a Member of a Group			(a) [X] (b) [   ]
3)	SEC Use Only
4)	Citizenship or Place of Organization			Delaware
Number of Shares Beneficially Owned by Each Reporting Person With		5)	Sole Voting Power	-0-
		6)	Shared Voting Power	-0-
		7)	Sole Dispositive Power	-0-
		8)	Shared Dispositive Power	-0-
9)	Aggregate Amount Beneficially Owned by Each Reporting Person			-0-
10)	Check if the Aggregate Amount in Row (9) Excludes Certain Shares			[   ]
11)	Percent of Class Represented by Amount in Row (9)			-0-
12)	Type of Reporting Person			PN

CUSIP No. 01438T106

Reference is hereby made to the statement on Schedule 13G filed with the Securities and Exchange Commission by the Reporting Persons on February 5, 2015 and Amendment No. 1 thereto filed on January 9, 2020 (as so amended, the “Schedule 13G”).  Terms defined in the Schedule 13G are used herein as so defined.

The following items of the Schedule 13G are hereby amended and restated as follows:

Item 2(b) – Address of Principal Business Office:

103 Carnegie Center, Suite 300, Princeton, NJ 08540

Item 4 – Ownership:

(a) through (c)  The information requested in these paragraphs is incorporated herein by reference to the cover pages to this Amendment No. 2 to Schedule 13G.

Item 5 – Ownership of Five Percent or Less of a Class:

If this statement is being filed to report the fact that the Reporting Persons have ceased to be the beneficial owners of more than five percent of the Common Stock, check the following:  [X]

CUSIP No. 01438T106

After reasonable inquiry and to the best of the undersigned’s knowledge and belief, the undersigned hereby certifies that the information set forth in this statement is true, complete and correct.

Dated:  January 4, 2022