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    Xencor Inc. filed SEC Form 8-K: Regulation FD Disclosure, Financial Statements and Exhibits

    10/24/25 1:57:11 PM ET
    $XNCR
    Biotechnology: Pharmaceutical Preparations
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    Get the next $XNCR alert in real time by email
    xncr-20251024
    FALSE000132673200013267322025-10-242025-10-24

    UNITED STATES
    SECURITIES AND EXCHANGE COMMISSION
    WASHINGTON, D.C. 20549
    ___________________________________________________
    FORM 8-K
    ___________________________________________________
    CURRENT REPORT
    Pursuant to Section 13 or 15(d)
    of The Securities Exchange Act of 1934
    Date of Report (Date of earliest event reported):  October 24, 2025
    ___________________________________________________
    XENCOR, INC.
    (Exact name of registrant as specified in its charter)
    ___________________________________________________
    Delaware
    001-3618220-1622502
    (State or Other Jurisdiction of
    Incorporation)
    (Commission
    File Number)
    (IRS Employer
    Identification Number)
    465 North Halstead Street, Suite 200
    Pasadena, California
    91107
    (Address of Principal Executive Offices)
    (Zip Code)
    (626) 305-5900
    (Registrant’s telephone number, including area code)
    (Former name or former address, if changed since last report)
    ___________________________________________________
    Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:
    o Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)
    o Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)
    o Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))
    o Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))
    Securities registered pursuant to Section 12(b) of the Act:
    Title of Each ClassTrading Symbol(s)Name of Each Exchange on Which Registered
    Common Stock, par value $0.01 per shareXNCRNasdaq Global Market
    Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§240.12b-2 of this chapter).
    Emerging growth company o
    If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. o



    Item 7.01. Regulation FD Disclosure.

    Xencor, Inc. (the “Company”) held a conference call on October 24, 2025 to discuss initial results from the ongoing Phase 1 dose-escalation study of XmAb819 (ENPP3 x CD3), early data from the ongoing Phase 1 dose-escalation study of XmAb541 (CLDN6 x CD3), and associated near-term clinical timelines. The Company has also made available on its website (www.xencor.com) presentation materials containing certain data from the ongoing clinical studies and certain forward-looking information.

    The information contained in, or that can be accessed through, the Company’s website is not a part of this filing. A copy of the presentation is furnished as Exhibit 99.1 to this Current Report on Form 8-K and incorporated herein by reference. The presentation is current as of April 29, 2025 and the Company disclaims any obligation to update this material.
    On October 24, 2025, the Company issued a press release announcing the initial results from the ongoing Phase 1 dose-escalation study of XmAb819 (ENPP3 x CD3) and associated near-term clinical timelines. A copy of the press release is furnished as Exhibit 99.2 to this Current Report on Form 8-K and incorporated herein by reference.

    The information furnished under this Item 7.01 of this Current Report on Form 8-K, including Exhibits 99.1 and 99.2 hereto, shall not be deemed “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the “Exchange Act”), or incorporated by reference in any filing under the Securities Act of 1933, as amended, or the Exchange Act, except as shall be expressly set forth by specific reference in such filing.
    Item 9.01. Financial Statements and Exhibits.
    (d)Exhibits.
    Exhibit No.Description
    99.1
    Presentation dated October 24, 2025.
    99.2
    Press release issued by Xencor, Inc. on October 24, 2025.
    104Cover Page Interactive Data File, formatted in Inline Extensible Business Reporting Language (iXBRL).



    SIGNATURES
    Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.
    Date: October 24, 2025
    XENCOR, INC.
    By:/s/ Celia Eckert
    Celia Eckert
    General Counsel & Corporate Secretary

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