G1 Therapeutics, Inc., a clinical-stage biopharmaceutical company, engages in the discovery, development, and commercialization of small molecule therapeutics for the treatment of patients with cancer. The company offers COSELA, which helps to decrease chemotherapy-induced myelosuppression in adult patients when administered prior to a platinum/etoposide-containing regimen or topotecan-containing regimen for extensive stage small cell lung cancer. It is also developing trilaciclib, an intravenous cyclin-dependent kinases (CDK) 4/6 inhibitor that is in Phase III clinical trials for patients with first line colorectal cancer, as well as Phase II clinical trials for the treatment of neoadjuvant breast cancer; lerociclib, an oral CDK4/6 inhibitor for multiple oncology indications; and rintodestrant, an oral selective estrogen receptor degrader, which is in Phase IIa clinical trials for the treatment of estrogen receptor-positive and HER2-negative breast cancer. The company has a collaboration with Quantum Leap Healthcare Collaborative to evaluate trilaciclib for neoadjuvant treatment of locally advanced breast cancer; and license agreement with EQRx, Inc. and Genor Biopharma Co. Inc. for the development and commercialization of lerociclib using an oral dosage form to treat any indication in humans, as well as Nanjing Simcere Dongyuan Pharmaceutical Co., LTD. for the development and commercialization of trilaciclib for any indication in humans through parenteral delivery, and ARC Therapeutics for the development and commercialization of a CDK2 inhibitor for all human and veterinary uses. G1 Therapeutics, Inc. was founded in 2008 and is headquartered in Research Triangle Park, North Carolina.
IPO Year: 2017
Exchange: NASDAQ
Website: g1therapeutics.com
| Date | Price Target | Rating | Analyst |
|---|---|---|---|
| 1/30/2023 | $7.00 → $10.00 | Underweight → Neutral | JP Morgan |
| 1/3/2023 | $32.00 → $31.00 | Buy | Needham |
| 11/4/2021 | $20.00 → $19.00 | Neutral → Underweight | JP Morgan |
| 11/4/2021 | $78.00 → $71.00 | Buy | HC Wainwright & Co. |
| 11/4/2021 | $41.00 → $24.00 | Outperform | Raymond James |
| 10/15/2021 | $51.00 | Buy | BTIG Research |
| 9/30/2021 | $24.00 → $20.00 | Overweight → Neutral | JP Morgan |
| 9/1/2021 | $57.00 → $56.00 | Buy | Roth Capital |
JP Morgan upgraded G1 Therapeutics from Underweight to Neutral and set a new price target of $10.00 from $7.00 previously
Needham reiterated coverage of G1 Therapeutics with a rating of Buy and set a new price target of $31.00 from $32.00 previously
JP Morgan downgraded G1 Therapeutics from Neutral to Underweight and set a new price target of $19.00 from $20.00 previously
HC Wainwright & Co. reiterated coverage of G1 Therapeutics with a rating of Buy and set a new price target of $71.00 from $78.00 previously
Raymond James reiterated coverage of G1 Therapeutics with a rating of Outperform and set a new price target of $24.00 from $41.00 previously
BTIG Research resumed coverage of G1 Therapeutics with a rating of Buy and set a new price target of $51.00
JP Morgan downgraded G1 Therapeutics from Overweight to Neutral and set a new price target of $20.00 from $24.00 previously
Roth Capital reiterated coverage of G1 Therapeutics with a rating of Buy and set a new price target of $56.00 from $57.00 previously
Needham & Company LLC reiterated coverage of G1 Therapeutics with a rating of Buy and set a new price target of $68.00 from $74.00 previously
Needham reiterated coverage of G1 Therapeutics with a rating of Buy and set a new price target of $68.00 from $74.00 previously
Submission status for G1 THERAPEUTICS INC's drug COSELA (ORIG-1) with active ingredient TRILACICLIB DIHYDROCHLORIDE has changed to 'Approval' on 02/12/2021. Application Category: NDA, Application Number: 214200, Application Classification: Type 1 - New Molecular Entity
Submission status for G1 THERAPEUTICS INC's drug COSELA (ORIG-1) with active ingredient TRILACICLIB has changed to 'Approval' on 02/12/2021. Application Category: NDA, Application Number: 214200, Application Classification: Type 1 - New Molecular Entity
For Immediate Release: February 12, 2021 Today, the U.S. Food and Drug Administration approved Cosela (trilaciclib) as the first therapy in its class to reduce the frequency of chemotherapy-induced bone marrow suppression in adults receiving certain types of chemotherapy for extensive-stage (when the cancer has spread beyond the lungs) small cell lung cancer. Cosela may help protect bone marrow cells from damage caused by chemotherapy by inhi
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S-8 POS - G1 Therapeutics, Inc. (0001560241) (Filer)
S-8 POS - G1 Therapeutics, Inc. (0001560241) (Filer)
S-8 POS - G1 Therapeutics, Inc. (0001560241) (Filer)
S-8 POS - G1 Therapeutics, Inc. (0001560241) (Filer)
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