Compare · MRK vs UPB
MRK vs UPB
Side-by-side comparison of Merck & Company Inc. (MRK) and Upstream Bio Inc. (UPB): market cap, price performance, sector, and recent activity on the wire.
Summary
- Both MRK and UPB operate in Biotechnology: Pharmaceutical Preparations (Health Care), so they compete in similar markets.
- MRK is the larger of the two at $385.99B, about 981.5x UPB ($393.3M).
- Over the past year, MRK is up 84.0% and UPB is down 58.5% - MRK leads by 142.6 points.
- MRK has been more active in the news (17 items in the past 4 weeks vs 4 for UPB).
- MRK has more recent analyst coverage (25 ratings vs 10 for UPB).
- Company
- Merck & Company Inc.
- Upstream Bio Inc.
- Price
- $156.44+3.81%
- $7.18+8.87%
- Market cap
- $385.99B
- $393.3M
- 1M return
- +19.67%
- +12.10%
- 1Y return
- +84.05%
- -58.52%
- Industry
- Biotechnology: Pharmaceutical Preparations
- Biotechnology: Pharmaceutical Preparations
- Exchange
- NYSE
- NASDAQ
- IPO
- 2024
- News (4w)
- 17
- 4
- Recent ratings
- 25
- 10
Merck & Company Inc.
Merck & Co., Inc. operates as a healthcare company worldwide. It operates through two segments, Pharmaceutical and Animal Health segments. The Pharmaceutical segment offers human health pharmaceutical products in the areas of oncology, hospital acute care, immunology, neuroscience, virology, cardiovascular, diabetes, and women's health, as well as vaccine products. The Animal Health segment provides discovers, develops, manufactures, and markets a range of veterinary pharmaceuticals, vaccines, and health management solutions and services, as well as a suite of digitally connected identification, traceability, and monitoring products. The company has collaborations with AstraZeneca PLC; Bayer AG; Eisai Co., Ltd.; and Ridgeback Biotherapeutics. It serves drug wholesalers and retailers, hospitals, and government agencies; managed health care providers, such as health maintenance organizations, pharmacy benefit managers, and other institutions; and physicians and physician distributors, veterinarians, and animal producers. The company has collaboration agreement with Gilead Sciences, Inc. to co-develop and co-commercialize long-acting investigational treatment combinations of Lenacapavir and Islatravir in HIV; Amathus Therapeutics to develop treatments for neurodegenerative diseases; and Linnaeus Therapeutics, Inc. to evaluate LNS8801 in combination with KEYTRUDA for patients with advanced cancer. It also has a collaboration with Biomed X Gmbh for building on ongoing research projects in the fields of oncology (DNA damage response and RNA splicing) and autoimmunity (intestinal epithelial barrier in autoimmune diseases); and a collaboration agreement with NGM Biopharmaceuticals, Inc. to focus primarily on the development of novel medicines for unmet patient needs in retinal and CVM diseases, including heart failure. Merck & Co., Inc. was founded in 1891 and is headquartered in Kenilworth, New Jersey.
Latest MRK
- Merck downgraded by RBC Capital Mkts with a new price target
- Merck upgraded by Morgan Stanley with a new price target
- Merck and Moderna Announce Phase 3 INTerpath-001 Trial of Intismeran Autogene Plus KEYTRUDA® Met Endpoints of Recurrence-Free Survival (RFS) and Distant Metastasis-Free Survival (DMFS) in Patients With Completely Resected Stage IIB-IV Melanoma
- EVP, Access, Policy & Comms Guindo Chirfi sold $1,350,000 worth of shares (10,000 units at $135.00), decreasing direct ownership by 21% to 36,613 units (SEC Form 4)
- EVP, General Counsel Zachary Jennifer exercised 54,927 shares at a strike of $109.78 and sold $10,718,495 worth of shares (80,315 units at $133.46), decreasing direct ownership by 36% to 45,509 units (SEC Form 4)
- EVP&Pres, Merck Animal Heallth Deluca Richard R. sold $5,942,369 worth of shares (45,320 units at $131.12), decreasing direct ownership by 29% to 110,167 units (SEC Form 4)
- Merck upgraded by Daiwa Securities with a new price target
- EVP&Pres, Merck Animal Heallth Deluca Richard R. sold $788,773 worth of shares (6,050 units at $130.38), decreasing direct ownership by 4% to 155,487 units (SEC Form 4)
- EVP & Pres. MMD Maraldo David R. exercised 18,706 shares at a strike of $82.25 and sold $2,407,797 worth of shares (18,706 units at $128.72) (SEC Form 4)
- EVP,Chief Info&Digital Officer Williams David Michael exercised 52,847 shares at a strike of $74.49 and sold $6,805,145 worth of shares (52,847 units at $128.77), increasing direct ownership by 0.00% to 31,716 units (SEC Form 4)
Latest UPB
- Amendment: SEC Form SCHEDULE 13G/A filed by Upstream Bio Inc.
- SEC Form 10-Q filed by Upstream Bio Inc.
- Upstream Bio Inc. filed SEC Form 8-K: Results of Operations and Financial Condition, Financial Statements and Exhibits
- Upstream Bio Reports Second Quarter 2026 Financial Results and Highlights Continued Progress
- SEC Form SCHEDULE 13G filed by Upstream Bio Inc.
- Chief Business Officer Houghton Adam sold $4,270 worth of shares (700 units at $6.10), decreasing direct ownership by 3% to 23,601 units (SEC Form 4) (for withholding tax)
- CFO and COO Gray Michael sold $5,203 worth of shares (853 units at $6.10), decreasing direct ownership by 3% to 28,795 units (SEC Form 4) to satisfy withholding obligation
- Chief Executive Officer Sutherland Everett Rand sold $12,780 worth of shares (2,095 units at $6.10), decreasing direct ownership by 3% to 70,812 units (SEC Form 4) to satisfy withholding obligation
- Chief Medical Officer Deykin Aaron sold $5,460 worth of shares (895 units at $6.10), decreasing direct ownership by 3% to 33,197 units (SEC Form 4) (for withholding tax)
- General Counsel Ambrose Allison sold $2,910 worth of shares (477 units at $6.10), decreasing direct ownership by 3% to 16,048 units (SEC Form 4) to satisfy withholding tax