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Compare · CLDX vs ORKA

CLDX vs ORKA

Side-by-side comparison of Celldex Therapeutics Inc. (CLDX) and Oruka Therapeutics Inc. (ORKA): market cap, price performance, sector, and recent activity on the wire.

Summary

  • Both CLDX and ORKA operate in Biotechnology: In Vitro & In Vivo Diagnostic Substances (Health Care), so they compete in similar markets.
  • ORKA is the larger of the two at $5.56B, about 2.0x CLDX ($2.77B).
  • Over the past year, CLDX is up 51.0% and ORKA is up 548.8% - ORKA leads by 497.8 points.
  • CLDX has been more active in the news (21 items in the past 4 weeks vs 4 for ORKA).
  • CLDX has more recent analyst coverage (21 ratings vs 11 for ORKA).
PerformanceCLDX+50.98%ORKA+548.77%
2025-07-25+0.00%2026-07-24
MetricCLDXORKA
Company
Celldex Therapeutics Inc.
Oruka Therapeutics Inc.
Price
$35.27-0.47%
$92.13+0.21%
Market cap
$2.77B
$5.56B
1M return
+4.44%
+12.13%
1Y return
+50.98%
+548.77%
Industry
Biotechnology: In Vitro & In Vivo Diagnostic Substances
Biotechnology: In Vitro & In Vivo Diagnostic Substances
Exchange
NASDAQ
NASDAQ
IPO
News (4w)
21
4
Recent ratings
21
11
CLDX

Celldex Therapeutics Inc.

Celldex Therapeutics, Inc., a biopharmaceutical company, engages in developing therapeutic monoclonal and bispecific antibodies for the treatment of various diseases. Its drug candidates include antibody-based therapeutics to treat patients with inflammatory diseases and various forms of cancer. The company's clinical development programs CDX-0159, a Phase I monoclonal antibody that binds the receptor tyrosine kinase KIT and inhibits its activity; CDX-1140, a human agonist monoclonal antibody targeted to CD40, a key activator of immune response, which is found on dendritic cells, macrophages, and B cells, as well as is expressed on various cancer cells; and CDX-527, a bispecific antibody, which uses the company's proprietary active anti-PD-L1 and CD27 human antibodies to couple CD27 costimulation with blockade of the PD-L1/PD-1 pathway to help prime and activate anti-tumor T cell responses through CD27 costimulation. Celldex Therapeutics, Inc. has research collaboration and license agreements with University of Southampton to develop human antibodies towards CD27; Amgen Inc. with exclusive rights to CDX-301 and CD40 ligand; and Yale University. The company was incorporated in 1983 and is headquartered in Hampton, New Jersey.

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