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Compare · ALGN vs POAI

ALGN vs POAI

Side-by-side comparison of Align Technology Inc. (ALGN) and Predictive Oncology Inc. (POAI): market cap, price performance, sector, and recent activity on the wire.

Summary

  • Both ALGN and POAI operate in Industrial Specialties (Health Care), so they compete in similar markets.
  • ALGN is the larger of the two at $12.76B, about 1028.1x POAI ($12.4M).
  • Over the past year, ALGN is down 6.9% and POAI is down 61.1% - ALGN leads by 54.1 points.
  • ALGN has hit the wire 16 times in the past 4 weeks while POAI has been quiet.
  • ALGN has more recent analyst coverage (25 ratings vs 2 for POAI).
PerformanceALGN+11.53%POAI-61.06%
2025-12-04+0.00%2026-06-10
MetricALGNPOAI
Company
Align Technology Inc.
Predictive Oncology Inc.
Price
$174.96-1.80%
$5.49-0.18%
Market cap
$12.76B
$12.4M
1M return
+6.20%
-16.18%
1Y return
-6.93%
-61.06%
Industry
Industrial Specialties
Industrial Specialties
Exchange
NASDAQ
NASDAQ
IPO
2001
News (4w)
16
0
Recent ratings
25
2
ALGN

Align Technology Inc.

Align Technology, Inc., a medical device company, designs, manufactures, and markets Invisalign clear aligners and iTero intraoral scanners and services for orthodontists and general practitioner dentists, and restorative and aesthetic dentistry. It operates in two segments, Clear Aligner; and Scanners and Services. The Clear Aligner segment consists of comprehensive products, including Invisalign comprehensive treatment that addresses the orthodontic needs of teenage patients, such as mandibular advancement, compliance indicators, and compensation for tooth eruption; and Invisalign First Phase I and Invisalign First Comprehensive Phase 2 package for younger patients generally between the ages of seven and ten years, which is a mixture of primary/baby and permanent teeth. This segment's non-comprehensive products comprise Invisalign moderate, lite and express packages, and Invisalign go; and non-case products include retention products, Invisalign training fees, and sales of ancillary products, such as cleaning material, and adjusting tools used by dental professionals during the course of treatment. The Scanners and Services segment offers iTero scanner, a single hardware platform with software options for restorative or orthodontic procedures; restorative software for general practitioner dentists, prosthodontists, periodontists, and oral surgeons; and software for orthodontists for digital records storage, orthodontic diagnosis, and for the fabrication of printed models and retainers. This segment also provides computer-aided design and computer-aided manufacturing services; ancillary products, such as disposable sleeves for the wand; iTero model and dies; third party scanners and digital scans; Invisalign outcome simulator, a chair-side and cloud-based application for the iTero scanner; Invisalign progress assessment tool; and TimeLapse technology, which allows doctors or practitioners to compare a patient's historic 3D scans to the present-day scan. The company sells its products in the United States, Switzerland, China, and internationally. Align Technology, Inc. was incorporated in 1997 and is headquartered in Tempe, Arizona.

POAI

Predictive Oncology Inc.

Predictive Oncology Inc. provides various healthcare products and services primarily in the United States. The company operates in three segments: Helomics, Soluble, and Skyline. The company manufactures environmentally conscious systems for the collection and disposal of infectious fluids that result from surgical procedures and post-operative care. It offers STREAMWAY System, a wall-mounted fully automated system that disposes suction fluid providing uninterrupted performance for physicians while virtually eliminating healthcare workers' exposure to infectious fluids collected during surgical and other patient procedures, as well as proprietary cleaning fluid and filters to users of its systems. The company also provides contract research organization (CRO) and AI-driven predictive models of tumor drug response to improve clinical outcomes to assist pharmaceutical, diagnostic, and biotech industries; and soluble and stable formulations for proteins, including vaccines, antibodies, and other protein therapeutics, as well as develops tumor models for precision cancer therapy and drug development. Its CRO services enhance the effectiveness of cancer therapy using the power of artificial intelligence (AI) applied to diseases databases. The company sells its medical device products directly to hospitals and other medical facilities through employed sales representatives, independent contractors, and distributors. The company was formerly known as Precision Therapeutics Inc. and changed its name to Predictive Oncology Inc. in June 2019. Predictive Oncology Inc. was incorporated in 2002 and is based in Eagan, Minnesota.

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