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Compare · SLNO vs TMDX

SLNO vs TMDX

Side-by-side comparison of Soleno Therapeutics Inc. (SLNO) and TransMedics Group Inc. (TMDX): market cap, price performance, sector, and recent activity on the wire.

Summary

  • Both SLNO and TMDX operate in Biotechnology: Electromedical & Electrotherapeutic Apparatus (Health Care), so they compete in similar markets.
  • SLNO is the larger of the two at $2.76B, about 1.2x TMDX ($2.32B).
  • Over the past year, SLNO is down 27.7% and TMDX is down 47.1% - SLNO leads by 19.4 points.
  • SLNO has been more active in the news (46 items in the past 4 weeks vs 17 for TMDX).
  • TMDX has more recent analyst coverage (18 ratings vs 12 for SLNO).
PerformanceSLNO-27.74%TMDX-53.04%
2025-05-30+0.00%2026-05-15
MetricSLNOTMDX
Company
Soleno Therapeutics Inc.
TransMedics Group Inc.
Price
$53.02+0.08%
$67.15-1.02%
Market cap
$2.76B
$2.32B
1M return
+0.76%
-31.87%
1Y return
-27.74%
-47.13%
Industry
Biotechnology: Electromedical & Electrotherapeutic Apparatus
Biotechnology: Electromedical & Electrotherapeutic Apparatus
Exchange
NASDAQ
NASDAQ
IPO
2014
2019
News (4w)
46
17
Recent ratings
12
18
SLNO

Soleno Therapeutics Inc.

Soleno Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on the development and commercialization of novel therapeutics for the treatment of rare diseases. Its lead candidate is Diazoxide Choline Controlled-Release (DCCR), a once-daily oral tablet for the treatment of Prader-Willi Syndrome (PWS), is being evaluated in a Phase III clinical development program. The company was formerly known as Capnia, Inc. and changed its name to Soleno Therapeutics, Inc. in May 2017. Soleno Therapeutics has collaboration with Vanderbilt University to discover and develop next generation K(ATP) channel activators for the treatment of rare diseases. Soleno Therapeutics, Inc. was incorporated in 1999 and is headquartered in Redwood City, California.

TMDX

TransMedics Group Inc.

TransMedics Group, Inc., a commercial-stage medical technology company, engages in transforming organ transplant therapy for end-stage organ failure patients in the United States and internationally. The company offers Organ Care System (OCS), a portable organ perfusion, optimization, and monitoring system that utilizes its proprietary and customized technology to replicate near-physiologic conditions for donor organs outside of the human body. Its Organ Care System includes OCS LUNG, a portable perfusion, ventilation, and monitoring system that maintains the organ at a near-physiologic state allowing physicians to assess and improve the condition of lungs between the donor and recipient sites; OCS Heart, a portable, warm perfusion, and monitoring system designed to keep a donor heart at a human-like, metabolically active state; and OCS Liver, a system that is evaluated in clinical trials for utilized and unutilized donor livers. TransMedics Group, Inc. was founded in 1998 and is headquartered in Andover, Massachusetts.

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