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    Amendment: SEC Form SCHEDULE 13D/A filed by Annexon Inc.

    11/21/25 7:27:18 PM ET
    $ANNX
    Biotechnology: Pharmaceutical Preparations
    Health Care
    Get the next $ANNX alert in real time by email



    SECURITIES AND EXCHANGE COMMISSION
    Washington, D.C. 20549


    SCHEDULE 13D

    Under the Securities Exchange Act of 1934

    (Amendment No. 2)


    Annexon, Inc.

    (Name of Issuer)


    Common Stock, par value $0.001

    (Title of Class of Securities)


    03589W102

    (CUSIP Number)


    Muneer A. Satter
    c/o Alerce Investment Management, L.P., 676 N. Michigan Avenue, Suite 4000
    Chicago, IL, 60611
    312-448-5500

    (Name, Address and Telephone Number of Person Authorized to Receive Notices and Communications)
    11/19/2025

    (Date of Event Which Requires Filing of This Statement)


    If the filing person has previously filed a statement on Schedule 13G to report the acquisition that is the subject of this Schedule 13D, and is filing this schedule because of §§ 240.13d-1(e), 240.13d-1(f) or 240.13d-1(g), check the following box. Checkbox checked

    The information required on the remainder of this cover page shall not be deemed to be “filed” for the purpose of Section 18 of the Securities Exchange Act of 1934 (“Act”) or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).






    SCHEDULE 13D

    CUSIP No.
    03589W102


    1 Name of reporting person

    Satter Muneer A
    2Check the appropriate box if a member of a Group (See Instructions)

    Checkbox not checked  (a)
    Checkbox not checked  (b)
    3SEC use only
    4 Source of funds (See Instructions)

    OO
    5 Check if disclosure of legal proceedings is required pursuant to Items 2(d) or 2(e)

    Checkbox not checked
    6Citizenship or place of organization

    UNITED STATES
    Number of Shares Beneficially Owned by Each Reporting Person With:
    7Sole Voting Power

    10,444,134.00
    8Shared Voting Power

    0.00
    9Sole Dispositive Power

    10,444,134.00
    10Shared Dispositive Power

    0.00
    11Aggregate amount beneficially owned by each reporting person

    10,444,134.00
    12Check if the aggregate amount in Row (11) excludes certain shares (See Instructions)

    Checkbox not checked
    13Percent of class represented by amount in Row (11)

    7.2 %
    14Type of Reporting Person (See Instructions)

    IN



    SCHEDULE 13D

    Item 1.Security and Issuer
    (a)Title of Class of Securities:

    Common Stock, par value $0.001
    (b)Name of Issuer:

    Annexon, Inc.
    (c)Address of Issuer's Principal Executive Offices:

    c/o Alerce Investment Management, L.P., 676 N. Michigan Avenue, Suite 4000, Chicago, ILLINOIS , 60611.
    Item 1 Comment:
    This Amendment No. 2 ("Amendment No. 2") amends and supplements the statement on Schedule 13D filed on July 18, 2022 (the "Original Filing") by Muneer A. Satter with respect to the common stock, par value $0.001 per share (the "Common Stock"), of Annexon, Inc. (the "Company"), as previously amended by Amendment No. 1 on February 17, 2023. The Original Filing as previously amended remains in effect except to the extent that it is amended, restated or superseded by information contained in this Amendment No. 2. Capitalized terms used and not defined in this Amendment No. 2 have the meanings set forth in the Original Filing as previously amended.
    Item 3.Source and Amount of Funds or Other Consideration
     
    Item 3 is hereby amended by the addition of the following: From November 17th through 21st, 2025, Alerce Medical purchased 2,322,613 shares of Common Stock on Nasdaq for an average price (excluding commissions) of $3.73 per share, in cash, for total consideration of approximately $8.7 million, as further detailed in Item 5(c). The source of funds for the acquisition of shares in the offering was working capital of Alerce Medical drawn from capital committed by some or all of its limited partners.
    Item 5.Interest in Securities of the Issuer
    (a)
    Item 5(a) is amended and restated as follows: See Items 11 and 13 of the cover pages. The aggregate percentage of Common Stock beneficially owned by Mr. Satter is based upon 145,261,154 shares outstanding, including 144,545,657 shares outstanding as disclosed by the Issuer on November 13, 2025 in a Prospectus Supplement filed with the SEC pursuant to Rule 424(b)(5), 613,497 shares of Common Stock that may be acquired upon the exercise of Common Warrants held by Alerce Medical, and 102,000 shares of Common Stock that may be acquired within 60 days of the date hereof pursuant to the exercise of stock options held by Mr. Satter.
    (b)
    Item 5(b) is amended and restated as follows: See Items 7, 8, 9 and 10 of the cover pages.
    (c)
    Item 5(c) is amended by the addition of the following tabular presentation of daily purchases of shares of Common Stock made for cash on the Nasdaq; in each case the daily average price is reported. November 17, 2025: 500,000 shares $2.99 November 18, 2025: 500,000 shares $3.18 November 19, 2025: 500,000 shares $3.94 November 20, 2025: 400,000 shares $4.48 November 21, 2025: 422,613 shares $4.28

        SIGNATURE 
     
    After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

     
    Satter Muneer A
     
    Signature:/s/ Muneer Satter
    Name/Title:Satter Muneer A
    Date:11/21/2025
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