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    Amendment: SEC Form SCHEDULE 13D/A filed by Repare Therapeutics Inc.

    11/21/25 8:24:54 PM ET
    $RPTX
    Biotechnology: Pharmaceutical Preparations
    Health Care
    Get the next $RPTX alert in real time by email



    SECURITIES AND EXCHANGE COMMISSION
    Washington, D.C. 20549


    SCHEDULE 13D

    Under the Securities Exchange Act of 1934

    (Amendment No. 6)


    Repare Therapeutics Inc.

    (Name of Issuer)


    Common Shares

    (Title of Class of Securities)


    760273102

    (CUSIP Number)


    Max Eisenberg
    One Sansome Street, Suite 1650
    San Francisco, CA, 94104
    415-801-8100

    (Name, Address and Telephone Number of Person Authorized to Receive Notices and Communications)
    11/19/2025

    (Date of Event Which Requires Filing of This Statement)


    If the filing person has previously filed a statement on Schedule 13G to report the acquisition that is the subject of this Schedule 13D, and is filing this schedule because of §§ 240.13d-1(e), 240.13d-1(f) or 240.13d-1(g), check the following box. Checkbox not checked

    The information required on the remainder of this cover page shall not be deemed to be “filed” for the purpose of Section 18 of the Securities Exchange Act of 1934 (“Act”) or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).






    SCHEDULE 13D

    CUSIP No.
    760273102


    1 Name of reporting person

    Versant Venture Capital V, L.P.
    2Check the appropriate box if a member of a Group (See Instructions)

    Checkbox not checked  (a)
    Checkbox checked  (b)
    3SEC use only
    4 Source of funds (See Instructions)

    WC
    5 Check if disclosure of legal proceedings is required pursuant to Items 2(d) or 2(e)

    Checkbox not checked
    6Citizenship or place of organization

    DELAWARE
    Number of Shares Beneficially Owned by Each Reporting Person With:
    7Sole Voting Power

    0.00
    8Shared Voting Power

    0.00
    9Sole Dispositive Power

    0.00
    10Shared Dispositive Power

    0.00
    11Aggregate amount beneficially owned by each reporting person

    0.00
    12Check if the aggregate amount in Row (11) excludes certain shares (See Instructions)

    Checkbox not checked
    13Percent of class represented by amount in Row (11)

    0.0 %
    14Type of Reporting Person (See Instructions)

    PN



    SCHEDULE 13D

    CUSIP No.
    760273102


    1 Name of reporting person

    Versant Affiliates Fund V, L.P.
    2Check the appropriate box if a member of a Group (See Instructions)

    Checkbox not checked  (a)
    Checkbox checked  (b)
    3SEC use only
    4 Source of funds (See Instructions)

    WC
    5 Check if disclosure of legal proceedings is required pursuant to Items 2(d) or 2(e)

    Checkbox not checked
    6Citizenship or place of organization

    DELAWARE
    Number of Shares Beneficially Owned by Each Reporting Person With:
    7Sole Voting Power

    2,693.00
    8Shared Voting Power

    0.00
    9Sole Dispositive Power

    2,693.00
    10Shared Dispositive Power

    0.00
    11Aggregate amount beneficially owned by each reporting person

    2,693.00
    12Check if the aggregate amount in Row (11) excludes certain shares (See Instructions)

    Checkbox not checked
    13Percent of class represented by amount in Row (11)

    0.0 %
    14Type of Reporting Person (See Instructions)

    PN

    Comment for Type of Reporting Person:
    All shares are held by VAF V (as defined in Item 2(a) of the Original 13D (as defined in Item 1 below)). VV V (as defined in Item 2(a) of the Original 13D) is the sole general partner of VAF V and may be deemed to have voting and dispositive power over the securities held by VAF V and as a result may be deemed to have beneficial ownership over such securities. The percentage in Row 13 is based on 42,985,755 Common Shares (as defined in Item 1 of the Original 13D) outstanding as of October 31, 2025, as set forth in the Issuer's quarterly report on Form 10-Q for the quarter ended September 30, 2025, filed with the United States Securities and Exchange Commission (the "Commission") on November 14, 2025 (the "Form 10-Q").


    SCHEDULE 13D

    CUSIP No.
    760273102


    1 Name of reporting person

    Versant Ophthalmic Affiliates I, L.P.
    2Check the appropriate box if a member of a Group (See Instructions)

    Checkbox not checked  (a)
    Checkbox checked  (b)
    3SEC use only
    4 Source of funds (See Instructions)

    WC
    5 Check if disclosure of legal proceedings is required pursuant to Items 2(d) or 2(e)

    Checkbox not checked
    6Citizenship or place of organization

    DELAWARE
    Number of Shares Beneficially Owned by Each Reporting Person With:
    7Sole Voting Power

    2,982.00
    8Shared Voting Power

    0.00
    9Sole Dispositive Power

    2,982.00
    10Shared Dispositive Power

    0.00
    11Aggregate amount beneficially owned by each reporting person

    2,982.00
    12Check if the aggregate amount in Row (11) excludes certain shares (See Instructions)

    Checkbox not checked
    13Percent of class represented by amount in Row (11)

    0.0 %
    14Type of Reporting Person (See Instructions)

    PN

    Comment for Type of Reporting Person:
    All shares are held by VOA (as defined in Item 2(a) of the Original 13D). VV V is the sole general partner of VOA and may be deemed to have voting and dispositive power over the securities held by VOA and as a result may be deemed to have beneficial ownership over such securities. The percentage in Row 13 is based on 42,985,755 Common Shares outstanding as of October 31, 2025, as reported in the Form 10-Q.


    SCHEDULE 13D

    CUSIP No.
    760273102


    1 Name of reporting person

    Versant Ventures V, LLC
    2Check the appropriate box if a member of a Group (See Instructions)

    Checkbox not checked  (a)
    Checkbox checked  (b)
    3SEC use only
    4 Source of funds (See Instructions)

    AF
    5 Check if disclosure of legal proceedings is required pursuant to Items 2(d) or 2(e)

    Checkbox not checked
    6Citizenship or place of organization

    DELAWARE
    Number of Shares Beneficially Owned by Each Reporting Person With:
    7Sole Voting Power

    0.00
    8Shared Voting Power

    5,675.00
    9Sole Dispositive Power

    0.00
    10Shared Dispositive Power

    5,675.00
    11Aggregate amount beneficially owned by each reporting person

    5,675.00
    12Check if the aggregate amount in Row (11) excludes certain shares (See Instructions)

    Checkbox not checked
    13Percent of class represented by amount in Row (11)

    0.0 %
    14Type of Reporting Person (See Instructions)

    OO

    Comment for Type of Reporting Person:
    The shares reported in Rows 8 and 10 consist of (i) 2,693 Common Shares held by VAF V and (ii) 2,982 Common Shares held by VOA. VV V is the sole general partner of each of VAF V and VOA and may be deemed to have voting and dispositive power over the securities held by each of VAF V and VOA. The percentage in Row 13 is based on 42,985,755 Common Shares outstanding as of October 31, 2025, as reported in the Form 10-Q.


    SCHEDULE 13D

    CUSIP No.
    760273102


    1 Name of reporting person

    Versant Venture Capital V (Canada) LP
    2Check the appropriate box if a member of a Group (See Instructions)

    Checkbox not checked  (a)
    Checkbox checked  (b)
    3SEC use only
    4 Source of funds (See Instructions)

    WC
    5 Check if disclosure of legal proceedings is required pursuant to Items 2(d) or 2(e)

    Checkbox not checked
    6Citizenship or place of organization

    ONTARIO, CANADA
    Number of Shares Beneficially Owned by Each Reporting Person With:
    7Sole Voting Power

    6,814.00
    8Shared Voting Power

    0.00
    9Sole Dispositive Power

    6,814.00
    10Shared Dispositive Power

    0.00
    11Aggregate amount beneficially owned by each reporting person

    6,814.00
    12Check if the aggregate amount in Row (11) excludes certain shares (See Instructions)

    Checkbox not checked
    13Percent of class represented by amount in Row (11)

    0.0 %
    14Type of Reporting Person (See Instructions)

    PN

    Comment for Type of Reporting Person:
    All shares held by VVC CAN (as defined in Item 2(a) of the Original 13D). VV V CAN GP (as defined in Item 2(a) of the Original 13D) is the sole general partner of VV V CAN (as defined in Item 2(a) of the Original 13D), and VV V CAN is the sole general partner of VVC CAN. Each of VV V CAN GP and VV V CAN share voting and dispositive power over the shares held by VVC CAN and as a result may be deemed to have beneficial ownership over such securities. The percentage in Row 13 is based on 42,985,755 Common Shares outstanding as of October 31, 2025, as reported in the Form 10-Q.


    SCHEDULE 13D

    CUSIP No.
    760273102


    1 Name of reporting person

    Versant Ventures V (Canada), L.P.
    2Check the appropriate box if a member of a Group (See Instructions)

    Checkbox not checked  (a)
    Checkbox checked  (b)
    3SEC use only
    4 Source of funds (See Instructions)

    AF
    5 Check if disclosure of legal proceedings is required pursuant to Items 2(d) or 2(e)

    Checkbox not checked
    6Citizenship or place of organization

    DELAWARE
    Number of Shares Beneficially Owned by Each Reporting Person With:
    7Sole Voting Power

    0.00
    8Shared Voting Power

    6,814.00
    9Sole Dispositive Power

    0.00
    10Shared Dispositive Power

    6,814.00
    11Aggregate amount beneficially owned by each reporting person

    6,814.00
    12Check if the aggregate amount in Row (11) excludes certain shares (See Instructions)

    Checkbox not checked
    13Percent of class represented by amount in Row (11)

    0.0 %
    14Type of Reporting Person (See Instructions)

    PN

    Comment for Type of Reporting Person:
    All shares held by VVC CAN. VV V CAN GP is the sole general partner of VV V CAN, and VV V CAN is the sole general partner of VVC CAN. Each of VV V CAN GP and VV V CAN share voting and dispositive power over the shares held by VVC CAN and as a result may be deemed to have beneficial ownership over such securities. The percentage in Row 13 is based on 42,985,755 Common Shares outstanding as of October 31, 2025, as reported in the Form 10-Q.


    SCHEDULE 13D

    CUSIP No.
    760273102


    1 Name of reporting person

    Versant Ventures V GP-GP (Canada), Inc.
    2Check the appropriate box if a member of a Group (See Instructions)

    Checkbox not checked  (a)
    Checkbox checked  (b)
    3SEC use only
    4 Source of funds (See Instructions)

    AF
    5 Check if disclosure of legal proceedings is required pursuant to Items 2(d) or 2(e)

    Checkbox not checked
    6Citizenship or place of organization

    DELAWARE
    Number of Shares Beneficially Owned by Each Reporting Person With:
    7Sole Voting Power

    0.00
    8Shared Voting Power

    6,814.00
    9Sole Dispositive Power

    0.00
    10Shared Dispositive Power

    6,814.00
    11Aggregate amount beneficially owned by each reporting person

    6,814.00
    12Check if the aggregate amount in Row (11) excludes certain shares (See Instructions)

    Checkbox not checked
    13Percent of class represented by amount in Row (11)

    0.0 %
    14Type of Reporting Person (See Instructions)

    CO

    Comment for Type of Reporting Person:
    All shares held by VVC CAN. VV V CAN GP is the sole general partner of VV V CAN, and VV V CAN is the sole general partner of VVC CAN. Each of VV V CAN GP and VV V CAN share voting and dispositive power over the shares held by VVC CAN and as a result may be deemed to have beneficial ownership over such securities. The percentage in Row 13 is based on 42,985,755 Common Shares outstanding as of October 31, 2025, as reported in the Form 10-Q.


    SCHEDULE 13D

    CUSIP No.
    760273102


    1 Name of reporting person

    Versant Venture Capital VI, L.P.
    2Check the appropriate box if a member of a Group (See Instructions)

    Checkbox not checked  (a)
    Checkbox checked  (b)
    3SEC use only
    4 Source of funds (See Instructions)

    WC
    5 Check if disclosure of legal proceedings is required pursuant to Items 2(d) or 2(e)

    Checkbox not checked
    6Citizenship or place of organization

    DELAWARE
    Number of Shares Beneficially Owned by Each Reporting Person With:
    7Sole Voting Power

    0.00
    8Shared Voting Power

    0.00
    9Sole Dispositive Power

    0.00
    10Shared Dispositive Power

    0.00
    11Aggregate amount beneficially owned by each reporting person

    0.00
    12Check if the aggregate amount in Row (11) excludes certain shares (See Instructions)

    Checkbox not checked
    13Percent of class represented by amount in Row (11)

    0.0 %
    14Type of Reporting Person (See Instructions)

    PN



    SCHEDULE 13D

    CUSIP No.
    760273102


    1 Name of reporting person

    Versant Ventures VI GP, L.P.
    2Check the appropriate box if a member of a Group (See Instructions)

    Checkbox not checked  (a)
    Checkbox checked  (b)
    3SEC use only
    4 Source of funds (See Instructions)

    AF
    5 Check if disclosure of legal proceedings is required pursuant to Items 2(d) or 2(e)

    Checkbox not checked
    6Citizenship or place of organization

    DELAWARE
    Number of Shares Beneficially Owned by Each Reporting Person With:
    7Sole Voting Power

    0.00
    8Shared Voting Power

    0.00
    9Sole Dispositive Power

    0.00
    10Shared Dispositive Power

    0.00
    11Aggregate amount beneficially owned by each reporting person

    0.00
    12Check if the aggregate amount in Row (11) excludes certain shares (See Instructions)

    Checkbox not checked
    13Percent of class represented by amount in Row (11)

    0.0 %
    14Type of Reporting Person (See Instructions)

    PN



    SCHEDULE 13D

    CUSIP No.
    760273102


    1 Name of reporting person

    Versant Ventures VI GP-GP, LLC
    2Check the appropriate box if a member of a Group (See Instructions)

    Checkbox not checked  (a)
    Checkbox checked  (b)
    3SEC use only
    4 Source of funds (See Instructions)

    AF
    5 Check if disclosure of legal proceedings is required pursuant to Items 2(d) or 2(e)

    Checkbox not checked
    6Citizenship or place of organization

    DELAWARE
    Number of Shares Beneficially Owned by Each Reporting Person With:
    7Sole Voting Power

    0.00
    8Shared Voting Power

    0.00
    9Sole Dispositive Power

    0.00
    10Shared Dispositive Power

    0.00
    11Aggregate amount beneficially owned by each reporting person

    0.00
    12Check if the aggregate amount in Row (11) excludes certain shares (See Instructions)

    Checkbox not checked
    13Percent of class represented by amount in Row (11)

    0.0 %
    14Type of Reporting Person (See Instructions)

    OO



    SCHEDULE 13D

    CUSIP No.
    760273102


    1 Name of reporting person

    Versant Vantage I, L.P.
    2Check the appropriate box if a member of a Group (See Instructions)

    Checkbox not checked  (a)
    Checkbox checked  (b)
    3SEC use only
    4 Source of funds (See Instructions)

    WC
    5 Check if disclosure of legal proceedings is required pursuant to Items 2(d) or 2(e)

    Checkbox not checked
    6Citizenship or place of organization

    DELAWARE
    Number of Shares Beneficially Owned by Each Reporting Person With:
    7Sole Voting Power

    72,211.00
    8Shared Voting Power

    0.00
    9Sole Dispositive Power

    72,211.00
    10Shared Dispositive Power

    0.00
    11Aggregate amount beneficially owned by each reporting person

    72,211.00
    12Check if the aggregate amount in Row (11) excludes certain shares (See Instructions)

    Checkbox not checked
    13Percent of class represented by amount in Row (11)

    0.2 %
    14Type of Reporting Person (See Instructions)

    PN

    Comment for Type of Reporting Person:
    All shares are held by Vantage LP (as defined in Item 2(a) of the Original 13D). Vantage LLC (as defined in the Original 13D) is the general partner of Vantage GP (as defined in Item 2(a) of the Original 13D), which is the general partner of Vantage LP. Each of Vantage LLC and Vantage GP share voting and dispositive power over the shares held by Vantage LP and as a result may be deemed to have beneficial ownership over such securities. The percentage in Row 13 is based on 42,985,755 Common Shares outstanding as of October 31, 2025, as reported in the Form 10-Q.


    SCHEDULE 13D

    CUSIP No.
    760273102


    1 Name of reporting person

    Versant Vantage I GP, L.P.
    2Check the appropriate box if a member of a Group (See Instructions)

    Checkbox not checked  (a)
    Checkbox checked  (b)
    3SEC use only
    4 Source of funds (See Instructions)

    AF
    5 Check if disclosure of legal proceedings is required pursuant to Items 2(d) or 2(e)

    Checkbox not checked
    6Citizenship or place of organization

    DELAWARE
    Number of Shares Beneficially Owned by Each Reporting Person With:
    7Sole Voting Power

    0.00
    8Shared Voting Power

    72,211.00
    9Sole Dispositive Power

    0.00
    10Shared Dispositive Power

    72,211.00
    11Aggregate amount beneficially owned by each reporting person

    72,211.00
    12Check if the aggregate amount in Row (11) excludes certain shares (See Instructions)

    Checkbox not checked
    13Percent of class represented by amount in Row (11)

    0.2 %
    14Type of Reporting Person (See Instructions)

    PN

    Comment for Type of Reporting Person:
    All shares are held by Vantage LP. Vantage LLC is the general partner of Vantage GP, which is the general partner of Vantage LP. Each of Vantage LLC and Vantage GP share voting and dispositive power over the shares held by Vantage LP and as a result may be deemed to have beneficial ownership over such securities. The percentage in Row 13 is based on 42,985,755 Common Shares outstanding as of October 31, 2025, as reported in the Form 10-Q.


    SCHEDULE 13D

    CUSIP No.
    760273102


    1 Name of reporting person

    Versant Vantage I GP-GP, LLC
    2Check the appropriate box if a member of a Group (See Instructions)

    Checkbox not checked  (a)
    Checkbox checked  (b)
    3SEC use only
    4 Source of funds (See Instructions)

    AF
    5 Check if disclosure of legal proceedings is required pursuant to Items 2(d) or 2(e)

    Checkbox not checked
    6Citizenship or place of organization

    DELAWARE
    Number of Shares Beneficially Owned by Each Reporting Person With:
    7Sole Voting Power

    0.00
    8Shared Voting Power

    72,211.00
    9Sole Dispositive Power

    0.00
    10Shared Dispositive Power

    72,211.00
    11Aggregate amount beneficially owned by each reporting person

    72,211.00
    12Check if the aggregate amount in Row (11) excludes certain shares (See Instructions)

    Checkbox not checked
    13Percent of class represented by amount in Row (11)

    0.2 %
    14Type of Reporting Person (See Instructions)

    OO

    Comment for Type of Reporting Person:
    All shares are held by Vantage LP. Vantage LLC is the general partner of Vantage GP, which is the general partner of Vantage LP. Each of Vantage LLC and Vantage GP share voting and dispositive power over the shares held by Vantage LP and as a result may be deemed to have beneficial ownership over such securities. The percentage in Row 13 is based on 42,985,755 Common Shares outstanding as of October 31, 2025, as reported in the Form 10-Q.


    SCHEDULE 13D

    Item 1.Security and Issuer
    (a)Title of Class of Securities:

    Common Shares
    (b)Name of Issuer:

    Repare Therapeutics Inc.
    (c)Address of Issuer's Principal Executive Offices:

    7171 Frederick Banting, Building 2, Suite 270, Saint-Laurent, Quebec, CANADA (FEDERAL LEVEL) , H4S 1Z9.
    Item 1 Comment:
    This Amendment No. 6 (this "Amendment") amends and supplements the Schedule 13D originally filed by the Reporting Persons with the Commission on July 7, 2020, as amended by Amendment No. 1 filed with the Commission on January 25, 2021, Amendment No. 2 filed with the Commission on February 26, 2021, Amendment No. 3 filed with the Commission on August 16, 2021, Amendment No. 4 filed with the Commission on June 13, 2022 and Amendment No. 5 filed with the Commission on January 6, 2023 (collectively, the "Original 13D"). Only those items that are hereby reported are amended; all other items reported in the Original 13D remain unchanged. Information given in response to each item shall be deemed incorporated by reference in all other items, as applicable. Capitalized terms not defined in this Amendment have the meanings ascribed to them in the Original 13D.
    Item 2.Identity and Background
    (b)
    One Sansome Street, Suite 1650, San Francisco, CA 94104
    Item 5.Interest in Securities of the Issuer
    (a)
    See Items 7-11 and 13 of the cover pages of this Amendment for each Reporting Person and the corresponding comments.
    (b)
    See Items 7-11 and 13 of the cover pages of this Amendment for each Reporting Person and the corresponding comments.
    (c)
    On November 19, 2025, VVC V sold 44,594 Common Shares at a price per share of $2.1605 for aggregate proceeds of approximately $96,345.34. On November 19, 2025, Versant VI sold 331,558 Common Shares at a price per share of $2.1605 for aggregate proceeds of approximately $716,331.06. On November 20, 2025, VVC V sold 237,107 Common Shares at a price per share of $2.1064 for aggregate proceeds of approximately $499,442.18. On November 20, 2025, Versant VI sold 1,762,893 Common Shares at a price per share of $2.1064 for aggregate proceeds of approximately $3,713,357.82. On November 20, 2025, Vantage LP sold 4,006 Common Shares at a price per share of $2.1275 for aggregate proceeds of approximately $8,522.77. On November 21, 2025, VAF V sold 5,782 Common Shares at a price per share of $2.1357 for aggregate proceeds of approximately $12,348.53. On November 21, 2025, VOA sold 6,399 Common Shares at a price per share of $2.1357 for aggregate proceeds of approximately $13,666.25. On November 21, 2025, VVC CAN sold 14,624 Common Shares at a price per share of $2.1357 for aggregate proceeds of approximately $31,232.26. On November 21, 2025, Vantage LP sold 154,994 Common Shares at a price per share of $2.1357 for aggregate proceeds of approximately $331,018.36.
    (e)
    November 20, 2025

        SIGNATURE 
     
    After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

     
    Versant Venture Capital V, L.P.
     
    Signature:/s/ Max Eisenberg
    Name/Title:Max Eisenberg, COO of Versant Ventures V, LLC the GP of Versant Venture Capital V, L.P.
    Date:11/21/2025
     
    Versant Affiliates Fund V, L.P.
     
    Signature:/s/ Max Eisenberg
    Name/Title:Max Eisenberg, COO of Versant Ventures V, LLC the GP of Versant Affiliates Fund V, L.P.
    Date:11/21/2025
     
    Versant Ophthalmic Affiliates I, L.P.
     
    Signature:/s/ Max Eisenberg
    Name/Title:Max Eisenberg, COO of Versant Ventures V, LLC the GP of Versant Ophthalmic Affiliates I, L.P.
    Date:11/21/2025
     
    Versant Ventures V, LLC
     
    Signature:/s/ Max Eisenberg
    Name/Title:Max Eisenberg, COO
    Date:11/21/2025
     
    Versant Venture Capital V (Canada) LP
     
    Signature:/s/ Max Eisenberg
    Name/Title:Max Eisenberg, COO of Versant Ventures V GP-GP (Canada), Inc., GP of Versant Ventures V (Canada), L.P., GP of Versant Venture Capital (Canada) LP
    Date:11/21/2025
     
    Versant Ventures V (Canada), L.P.
     
    Signature:/s/ Max Eisenberg
    Name/Title:Max Eisenberg, COO of Versant Ventures V GP-GP (Canada), Inc. the GP of Versant Ventures V (Canada), L.P.
    Date:11/21/2025
     
    Versant Ventures V GP-GP (Canada), Inc.
     
    Signature:/s/ Max Eisenberg
    Name/Title:Max Eisenberg, COO
    Date:11/21/2025
     
    Versant Venture Capital VI, L.P.
     
    Signature:/s/ Max Eisenberg
    Name/Title:Max Eisenberg, COO of Versant Ventures VI GP-GP, LLC the GP of Versant Ventures VI GP, L.P. the GP of Versant Venture Capital VI, L.P.
    Date:11/21/2025
     
    Versant Ventures VI GP, L.P.
     
    Signature:/s/ Max Eisenberg
    Name/Title:Max Eisenberg, COO of Versant Ventures VI GP-GP, LLC the GP of Versant Ventures VI GP, L.P.
    Date:11/21/2025
     
    Versant Ventures VI GP-GP, LLC
     
    Signature:/s/ Max Eisenberg
    Name/Title:Max Eisenberg, COO
    Date:11/21/2025
     
    Versant Vantage I, L.P.
     
    Signature:/s/ Max Eisenberg
    Name/Title:Max Eisenberg, COO of Versant Vantage I GP-GP, LLC the GP of Versant Vantage I GP, L.P. the GP of Versant Vantage I, L.P.
    Date:11/21/2025
     
    Versant Vantage I GP, L.P.
     
    Signature:/s/ Max Eisenberg
    Name/Title:Max Eisenberg, COO of Versant Vantage I GP-GP, LLC the GP of Versant Vantage I GP, L.P.
    Date:11/21/2025
     
    Versant Vantage I GP-GP, LLC
     
    Signature:/s/ Max Eisenberg
    Name/Title:Max Eisenberg, COO
    Date:11/21/2025
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    4/12/2022$11.00Buy → Hold
    Stifel
    3/17/2022$43.00Buy
    Goldman
    9/23/2021$48.00Buy
    Stifel
    9/13/2021$54.00Buy
    HC Wainwright & Co.
    8/16/2021$45.00 → $47.00Overweight
    Morgan Stanley
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    $RPTX
    SEC Filings

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    Amendment: SEC Form SCHEDULE 13D/A filed by Repare Therapeutics Inc.

    SCHEDULE 13D/A - Repare Therapeutics Inc. (0001808158) (Subject)

    11/21/25 8:24:54 PM ET
    $RPTX
    Biotechnology: Pharmaceutical Preparations
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    SEC Form DEFA14A filed by Repare Therapeutics Inc.

    DEFA14A - Repare Therapeutics Inc. (0001808158) (Filer)

    11/20/25 5:29:08 PM ET
    $RPTX
    Biotechnology: Pharmaceutical Preparations
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    SEC Form DEFA14A filed by Repare Therapeutics Inc.

    DEFA14A - Repare Therapeutics Inc. (0001808158) (Filer)

    11/17/25 9:21:45 AM ET
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    Insider Trading

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    SVP, Finance and CAO Alves Sandra Isabelle Barros was granted 4,100 shares, increasing direct ownership by 16% to 29,622 units (SEC Form 4)

    4 - Repare Therapeutics Inc. (0001808158) (Issuer)

    4/29/25 5:07:34 PM ET
    $RPTX
    Biotechnology: Pharmaceutical Preparations
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    New insider Alves Sandra Isabelle Barros claimed ownership of 25,522 shares (SEC Form 3)

    3 - Repare Therapeutics Inc. (0001808158) (Issuer)

    4/29/25 5:05:52 PM ET
    $RPTX
    Biotechnology: Pharmaceutical Preparations
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    SEC Form 4 filed by EVP, CHIEF FINANCIAL OFFICER Forte Steve

    4 - Repare Therapeutics Inc. (0001808158) (Issuer)

    4/4/25 4:15:09 PM ET
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    Analyst Ratings

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    Repare Therapeutics upgraded by Stifel with a new price target

    Stifel upgraded Repare Therapeutics from Hold to Buy and set a new price target of $16.00 from $11.00 previously

    6/9/23 7:34:45 AM ET
    $RPTX
    Biotechnology: Pharmaceutical Preparations
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    Repare Therapeutics downgraded by Morgan Stanley with a new price target

    Morgan Stanley downgraded Repare Therapeutics from Overweight to Equal-Weight and set a new price target of $15.00 from $28.00 previously

    2/3/23 7:35:18 AM ET
    $RPTX
    Biotechnology: Pharmaceutical Preparations
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    CapitalOne initiated coverage on Repare Therapeutics with a new price target

    CapitalOne initiated coverage of Repare Therapeutics with a rating of Overweight and set a new price target of $28.00

    1/6/23 8:30:21 AM ET
    $RPTX
    Biotechnology: Pharmaceutical Preparations
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    $RPTX
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    Repare Therapeutics Enters into Support and Voting Agreements with Significant Shareholders for Proposed Transaction with XenoTherapeutics, Inc.

    Repare Therapeutics Inc. ("Repare" or the "Company") (NASDAQ:RPTX), a clinical-stage precision oncology company, today announced that following the announcement on November 14, 2025 of the entering into of a definitive arrangement agreement with XenoTherapeutics, Inc. and Xeno Acquisition Corp. (jointly, "Xeno"), a non-profit biotechnology company, pursuant to which Xeno will acquire (the "Transaction") all of the issued and outstanding common shares of Repare (the "Common Shares"), certain entities affiliated with BVF Partners L.P., Blue Owl Healthcare Opportunities, and certain entities affiliated with OrbiMed have each entered into a support and voting agreement pursuant to which they ha

    11/20/25 5:25:00 PM ET
    $RPTX
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Key Catalysts Emerge in Oncology, Synthetic Biology, and M&A Activity as Markets Open

    DENVER, Nov. 17, 2025 (GLOBE NEWSWIRE) -- Markets open this morning with a distinctly biotech-heavy narrative delivering milestone developments. Zymeworks and Jazz Drop Landmark Phase 3 Data: Ziihera Positioned as New HER2 Standard in First-Line GEA The biggest headline of the morning comes from Zymeworks (NASDAQ:ZYME), after partners Jazz Pharmaceuticals and BeOne Medicines unveiled positive top-line results from the Phase 3 HERIZON-GEA-01 study evaluating Ziihera (zanidatamab-hrii) in front-line HER2-positive gastroesophageal adenocarcinoma (GEA). Why it matters: This is the first Phase 3 trial to show superiority over the long-standing regimen trastuzumab + chemotherapy, positioning

    11/17/25 10:48:19 AM ET
    $GLMD
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    $ZYME
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    Repare Therapeutics Enters into Definitive Agreement to be Acquired by XenoTherapeutics, Inc.

    - Each shareholder is estimated to receive US$1.82 per share plus one CVR per common share - - Transaction expected to close in the first quarter of 2026 - - Additional portfolio monetization efforts continue - - Company reports 3Q 2025 financial results - - $112.6 million in cash and cash equivalents and marketable securities as of September 30, 2025, as compared to $109.5 million at June 30, 2025 - Repare Therapeutics Inc. ("Repare" or the "Company") (NASDAQ:RPTX), a clinical-stage precision oncology company, today announced that it has entered into a definitive arrangement agreement (the "Arrangement Agreement") with XenoTherapeutics, Inc. and Xeno Acquisition Corp. (jointly, "

    11/14/25 4:44:00 PM ET
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    $RPTX
    Insider Purchases

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    Bvf Partners L P/Il bought $6,249,889 worth of shares (1,227,301 units at $5.09) (SEC Form 4)

    4 - Repare Therapeutics Inc. (0001808158) (Issuer)

    11/17/23 4:54:43 PM ET
    $RPTX
    Biotechnology: Pharmaceutical Preparations
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    Bvf Partners L P/Il bought $2,821,352 worth of shares (783,709 units at $3.60) (SEC Form 4)

    4 - Repare Therapeutics Inc. (0001808158) (Issuer)

    11/3/23 5:37:44 PM ET
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    $RPTX
    Leadership Updates

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    OMass Therapeutics Appoints Carol A. Schafer as Non-Executive Director and Chair of the Audit Committee

    PRESS RELEASE OMass Therapeutics Appoints Carol A. Schafer as Non-Executive Director and Chair of the Audit Committee Oxford, United Kingdom – 6th August 2025 – OMass Therapeutics (‘OMass' or ‘the Company'), a biotechnology company identifying medicines against highly validated target ecosystems such as membrane proteins or intracellular complexes, today announces the appointment of Carol A. Schafer as non-executive Director and Chair of the Audit Committee. Carol has more than 25 years of experience in investment banking, equity capital markets, corporate finance and business development in the healthcare sector. She currently serves on the Board of Directors for Insmed Incorporated (NAS

    8/6/25 7:00:00 AM ET
    $IMNM
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    $KURA
    Biotechnology: Pharmaceutical Preparations
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    Repare Therapeutics Provides Business and Clinical Update and Reports First Quarter 2024 Financial Results

    Phase 1 MYTHIC clinical trial of lunresertib in combination with camonsertib demonstrated a significant reduction in Grade 3 anemia and continued trends of patient response and benefit; FDA agrees with RP2D             First patient dosed in Phase 1 MYTHIC clinical trial of lunresertib in combination with the WEE1 inhibitor, Debio 0123; first clinical trial inhibiting both PKMYT1 and WEE1 Initiating Phase 2 TRESR expansion in ~20 patients evaluating monotherapy camonsertib in NSCLC; initial data expected in 2025 First patient dosed in Phase 1 LIONS monotherapy trial for PLK4 inhibitor RP-1664 Announced the appointment of Steven H. Stein, M.D. to Repare's Board of Directors, effecti

    5/7/24 4:05:00 PM ET
    $RPTX
    Biotechnology: Pharmaceutical Preparations
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    Repare Therapeutics Appoints Steven H. Stein, M.D. to its Board of Directors

    Repare Therapeutics Inc. ("Repare" or the "Company") (NASDAQ:RPTX), a leading clinical-stage precision oncology company, today announced the appointment of Steven H. Stein, M.D., to its Board of Directors, effective as of the date of the Company's upcoming annual meeting of shareholders in June 2024. The Company also announces that Todd Foley has decided not to stand for re-election as a director of the Company following the end of his current term as a Class I director on June 17, 2024, after serving more than seven years on the Board. "On behalf of the Company and our Board of Directors, we thank Todd for his dedication and partnership, which have played a crucial role in shaping Repare

    4/26/24 4:05:00 PM ET
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    Newly Launched DCx Biotherapeutics In-Licenses Discovery Platforms and Retains Talent and Infrastructure From Repare Therapeutics to Accelerate Development of Multi-Modal Antibody Drug Conjugates

    Combines cancer biology, genetics, medicinal chemistry, and biologics research and development experience to rapidly advance a broad pipeline of preclinical oncology programs against genetically-defined cancers Licenses Repare's SNIPRx®, SNIPRx-surf, and STEP2 platforms for discovering druggable intracellular and synergistic cell-surface targets and identifying small molecules sensitive to specific cancer lesions Licenses preclinical small molecule and antibody programs for developing antibody drug conjugates Supported by DCx's co-founding investor, Amplitude Ventures, to create a leading company in developing differentiated first-in-class precision drug conjugates DCx Biotherapeut

    5/1/25 7:00:00 AM ET
    $RPTX
    Biotechnology: Pharmaceutical Preparations
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    Repare Therapeutics Announces Positive Results of the Lunresertib and Camonsertib Combination from the MYTHIC Phase 1 Gynecologic Expansion Clinical Trial

    Heavily-pretreated patients on lunresertib and camonsertib combination achieved 25.9% overall response rate (ORR) in endometrial cancer and 37.5% in platinum-resistant ovarian cancer Nearly half of patients with gynecologic cancers maintained progression-free survival at 24 weeks, comparing favorably to current standard of care Company plans to initiate a registrational Phase 3 trial of lunresertib in combination with camonsertib in endometrial cancer in 2H 2025 Repare to host conference call and webcast today at 4:30 p.m. ET to discuss these results Repare Therapeutics Inc. ("Repare" or the "Company") (NASDAQ:RPTX), a leading clinical-stage precision oncology company, today reporte

    12/12/24 4:20:00 PM ET
    $RPTX
    Biotechnology: Pharmaceutical Preparations
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    Repare Therapeutics to Host Webcast to Report Data from the Lunresertib and Camonsertib Combination Phase 1 MYTHIC Clinical Trial

    Event to be webcast live on Thursday, December 12 at 4:30 p.m. ET Repare Therapeutics Inc. ("Repare" or the "Company") (NASDAQ:RPTX), a leading clinical-stage precision oncology company, today announced it will host a conference call and live webcast to present the latest data from its ongoing Phase 1 MYTHIC clinical trial evaluating lunresertib in combination with camonsertib at the recommended Phase 2 dose in an expansion cohort in patients with platinum-resistant ovarian and endometrial cancers harboring CCNE1 amplification or FBXW7 or PPP2R1A mutations, on Thursday, December 12, 2024 at 4:30 p.m. Eastern Time. Repare's executive management team will be joined by Brian Slomovitz, M.D.,

    12/10/24 4:05:00 PM ET
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    Large Ownership Changes

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    Amendment: SEC Form SC 13G/A filed by Repare Therapeutics Inc.

    SC 13G/A - Repare Therapeutics Inc. (0001808158) (Subject)

    11/14/24 9:00:57 PM ET
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    Biotechnology: Pharmaceutical Preparations
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    Amendment: SEC Form SC 13G/A filed by Repare Therapeutics Inc.

    SC 13G/A - Repare Therapeutics Inc. (0001808158) (Subject)

    11/14/24 5:05:19 PM ET
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    Biotechnology: Pharmaceutical Preparations
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    Amendment: SEC Form SC 13G/A filed by Repare Therapeutics Inc.

    SC 13G/A - Repare Therapeutics Inc. (0001808158) (Subject)

    11/14/24 9:42:55 AM ET
    $RPTX
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