Issued patents provide intellectual property protection for clinical candidates, AP-SA02 and AP-PA02, until at least 2041

LOS ANGELES, Oct. 7, 2026 /PRNewswire/ -- Armata Pharmaceuticals, Inc. (NYSE:ARMP) ("Armata" or the "Company"), a late clinical-stage biotechnology company focused on the development of high-purity and potency, pathogen-specific bacteriophage therapeutics for the treatment of antibiotic-resistant and difficult-to-treat bacterial infections, today announced issuance of two patents by the United States Patent and Trademark Office ("USPTO") covering its bacteriophage programs, AP-SA02 and AP-PA02. These newly issued U.S. patents support Armata's leadership in bacteriophage therapeutics and specifically, strengthen the intellectual property ("IP") around the AP-SA02 and AP-PA02 programs, which are highly impactful and potential first- and best-in-class therapies. With patent protection extending into at least 2041, Armata's programs are supported by a robust, long-term IP foundation, with additional patents pending.

Dr. Deborah Birx, Chief Executive Officer of Armata, said, "These are two important patents for our Company. Not only do they strengthen our programs in Staphylococcus aureus and Pseudomonas aeruginosa, but they also exemplify our strategy of protecting each phage cocktail that is created using our proprietary phage platform. With the rapidly growing interest in phage-based therapeutics as a potentially improved treatment option against antibiotic-resistant and difficult-to-treat bacterial strains, our intellectual property is increasingly vital to protecting our position as a leader in this promising treatment modality. The issuance of these key patents further reinforces the uniqueness of our bacteriophage programs and our Phase 3-ready candidate, AP-SA02, which is scheduled to enter a superiority study later this year."

Armata's bacteriophage intellectual property portfolio includes 15 patent families with issued or pending claims covering the Company's bacteriophage development programs. With these issuances, the company's global IP portfolio consists of 101 issued patents (15 U.S. and 86 ex-U.S.) and 60 pending patent applications (9 U.S. and 51 ex-U.S.) with nominal expiration dates through 2046.

Details of the newly allowed patents are as follows:

U.S. Patent No. 12,751,983: Bacteriophage Compositions For Treating Staphylococcus Infection

Issued on October 6, 2026, protects methods of treating Staphylococcus aureus infections using its lead product candidate, AP-SA02, which is currently in development for adjunct treatment of complicated Staphylococcus aureus bacteremia ("SAB") caused by methicillin-sensitive S. aureus ("MSSA") or methicillin-resistant S. aureus ("MRSA"). The patent is expected to provide patent protection until at least February 2041, and may be eligible for patent term adjustments or patent term extensions affording even later protection.

U.S. Patent No. 12,594,312: Bacteriophage Compositions For Treating Pseudomonas Infection

Issued on April 7, 2026, protects methods of treating Pseudomonas infections using its clinical candidate, AP-PA02, which is in development against various diseases or indications caused by Pseudomonas infections. The patent is expected to provide patent protection until about January 4, 2043 which includes 617 days of patent term adjustments, and this case may be eligible as well for patent term extensions affording even later protection.

About AP-SA02

Armata is developing AP-SA02, a fixed multi-phage cocktail, for the adjunct treatment of complicated Staphylococcus aureus bacteremia caused by methicillin-sensitive S. aureus (MSSA) or methicillin-resistant S. aureus (MRSA). AP-SA02 has received Qualified Infectious Disease Product (QIDP) designation, Fast Track designation, and Breakthrough Therapy designation from the FDA. The diSArm study (NCT05184764) was a Phase 1b/2a, multicenter, randomized, double-blind, placebo-controlled, multiple ascending dose escalation study of the safety, tolerability, and efficacy of intravenous AP-SA02 in addition to best available antibiotic therapy ("BAT") compared to BAT alone (placebo) for the treatment of adults with complicated S. aureus bacteremia. Positive results from the Phase 2a diSArm study were highlighted in a late-breaking oral presentation at IDWeek 2025™ in October 2025. The Company plans to advance AP-SA02 into a Phase 3 superiority study in complicated SAB, anticipated to initiate in the second half of 2026.

About AP-PA02

Armata is developing AP-PA02 as a potential treatment for chronic respiratory infections due to Pseudomonas aeruginosa in people with cystic fibrosis (CF) and with non-cystic fibrosis bronchiectasis (NCFB). AP-PA02 has shown promising results in two Phase 2 clinical trials to date, SWARM-P.a. (NCT04596319) and Tailwind (NCT05616221).

About Armata Pharmaceuticals, Inc.

Armata is a late clinical-stage biotechnology company focused on the development of high-purity and potency, pathogen-specific bacteriophage therapeutics for the treatment of antibiotic-resistant and difficult-to-treat bacterial infections using its proprietary bacteriophage-based technology. Armata is developing and advancing a broad pipeline of natural and synthetic phage candidates, including clinical candidates for Pseudomonas aeruginosa, Staphylococcus aureus, and other important pathogens. Armata is committed to advancing phage therapy with drug development expertise that spans bench to clinic including in-house phage-specific current Good Manufacturing Practices ("cGMP") manufacturing to support full commercialization.

Forward Looking Statements

This communication contains "forward-looking" statements as defined by the Private Securities Litigation Reform Act of 1995. These statements relate to future events, results or to Armata's future financial performance and involve known and unknown risks, uncertainties and other factors which may cause Armata's actual results, performance or events to be materially different from any future results, performance or events expressed or implied by the forward-looking statements. In some cases, you can identify these statements by terms such as "anticipate," "believe," "could," "estimate," "expect," "intend," "may," "plan," "potential," "predict," "project," "should," "will," "would" or the negative of those terms, and similar expressions. These forward-looking statements reflect management's beliefs and views with respect to future events and are based on estimates and assumptions as of the date of this communication and are subject to risks and uncertainties including risks related to Armata's development of bacteriophage-based therapies; Armata's planned clinical trials; ability to staff and maintain its production facilities under fully compliant cGMP; ability to meet anticipated milestones in the development and testing of the relevant product; ability to be a leader in the development of phage-based therapeutics; ability to achieve its vision, including improvements through engineering and success of clinical trials; ability to successfully complete preclinical and clinical development of, and obtain regulatory approval of its product candidates and commercialize any approved products on its expected timeframes or at all; and Armata's estimates regarding anticipated operating losses, capital requirements and needs for additional funds. Additional risks and uncertainties relating to Armata and its business can be found under the caption "Risk Factors" and elsewhere in Armata's filings and reports with the U.S. Securities and Exchange Commission (the "SEC"), including in Armata's Annual Report on Form 10-K, filed with the SEC on March 25, 2026, and in its subsequent filings with the SEC.

Armata expressly disclaims any obligation or undertaking to release publicly any updates or revisions to any forward-looking statements contained herein to reflect any change in Armata's expectations with regard thereto or any change in events, conditions or circumstances on which any such statements are based.

Media Contacts:

At Armata:

Pierre Kyme

ir@armatapharma.com

310-665-2928

Investor Relations:

Joyce Allaire

LifeSci Advisors, LLC

jallaire@lifesciadvisors.com

212-915-2569

612660624v.1

View original content to download multimedia:https://www.prnewswire.com/news-releases/armata-pharmaceuticals-strengthens-intellectual-property-portfolio-with-two-recent-patent-issuances-in-the-united-states-302900574.html

SOURCE Armata Pharmaceuticals, Inc.