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EVP & Pres Med.Essntl&BioPharm Garrison Michael David exercised 3,054 shares at a strike of $167.91, returned $512,886 worth of shares to the company (2,454 units at $209.00) and sold $334,005 worth of shares (1,610 units at $207.46), decreasing direct ownership by 8% to 12,095 units (SEC Form 4)

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