SEC FORM 4

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SEC filings, FDA approvals, analyst ratings, insider trading, press releases, and more - streamed in real time.","publisher":{"@id":"https://www.quantisnow.com#organization"},"inLanguage":"en-US","potentialAction":{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https://www.quantisnow.com/news?q={search_term_string}"},"query-input":"required name=search_term_string"}}]44:["$","div",null,{"className":"grid grid-cols-1 xl:grid-cols-[1fr_340px]","children":[["$","$L5e",null,{"newsitemId":4813611}],["$","script",null,{"type":"application/ld+json","dangerouslySetInnerHTML":{"__html":"$5f"}}],["$","article",null,{"className":"min-w-0 px-4 pb-16 pt-6 sm:px-8 xl:hairline-r xl:px-10","children":[["$","div",null,{"className":"mb-6 flex items-center justify-between text-[12px] text-muted-foreground","children":[["$","$L2c",null,{"ref":"$undefined","prefetch":false,"href":"/news","className":"inline-flex h-8 items-center gap-1.5 rounded-full border border-hairline-strong px-3 text-[13px] font-medium text-muted-foreground transition-colors hover:bg-surface hover:text-foreground","children":[[["$","$L2d",null,{"ref":"$undefined","icon":"$17:props:children:1:props:children:0:0:props:icon","className":"h-3.5 w-3.5"}]," Live feed"],["$","$L2f",null,{}]]}],["$","div",null,{"className":"flex items-center gap-2 font-mono text-[11px] tabular-nums","children":[["$","$L60",null,{"iso":"2023-07-28 20:12:44.000000","mode":"clock","className":"text-foreground"}],"$L61","$L62"]}]]}],"$L63","$L64","$L65","$L66","$L67","$L68","$L69","$L6a","$L6b"]}],"$L6c","$L6d"]}] 6e:I[303278,["$3","$4","$5","$6","$7","$8","$a","$b","$c"],"SaveStoryButton"] 73:I[258499,["$3","$4","$5","$6","$7","$8","$a","$b","$c"],"CompanyLogo"] 74:"PlusAlertCallout" 75:I[928072,["$3","$4","$5","$6","$7","$8","$a","$b","$c"],"$74"] 76:I[840710,["$3","$4","$5","$6","$7","$8","$a","$b","$c"],"InsightPaywall"] 77:I[618021,["$3","$4","$5","$6","$7","$8","$a","$b","$c"],"ArticleFrame"] 79:I[423255,["$3","$4","$5","$6","$7","$8","$a","$b","$c"],"InlineSignupCta"] 7a:I[265232,["$3","$4","$5","$6","$7","$8","$a","$b","$c"],"IveHadItCallout"] 7b:"ConversionCtaBar" 7c:I[199759,["$3","$4","$5","$6","$7","$8","$a","$b","$c"],"$7b"] 61:["$","span",null,{"className":"text-dim-foreground","children":"·"}] 62:["$","$L60",null,{"iso":"2023-07-28 20:12:44.000000","mode":"relative","className":"text-dim-foreground"}] 6f:T4009, SEC FORM 4 SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL

OMB Number:			3235-0287
Estimated average burden
hours per response:			0.5

Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

1. Name and Address of Reporting Person^*

Derby Michael

(Last)

(First)

(Middle)

C/O PAXMEDICA, INC.

303 SOUTH BROADWAY, SUITE 125

(Street)

TARRYTOWN

10591

(City)

(State)

(Zip)

2. Issuer Name and Ticker or Trading Symbol
PaxMedica, Inc. [ PXMD ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

X	Director	10% Owner
X	Officer (give title below)	Other (specify below)
Executive Chairman

3. Date of Earliest Transaction (Month/Day/Year)
07/26/2023

4. If Amendment, Date of Original Filed (Month/Day/Year)

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	Code	V	Amount	(A) or (D)	Price		6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
Common Stock	07/26/2023		F⁽¹⁾		6,272	D	$0.717	461,886	D
Common Stock								7,336,745	I	TardiMed Sciences, LLC⁽²⁾

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares	8. Price of Derivative Security (Instr. 5)		10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)

Explanation of Responses:

1. Shares withheld by issuer to satisfy tax withholding obligations of reporting person resulting from vesting of restricted stock units.

2. The reporting person is the Managing Partner of TardiMed and has sole voting and dispositive control over the shares of Common Stock held by the entity. The reporting person disclaims beneficial ownership of these securities except to the extent of his pecuniary interest therein.

	/s/ Stephen D. Sheldon, Jr. Attorney-in-Fact	07/28/2023
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.

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FORM 4

OMB APPROVAL

OMB Number:			3235-0287
Estimated average burden
hours per response:			0.5

Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

1. Name and Address of Reporting Person^*

Derby Michael

(Last)

(First)

(Middle)

C/O PAXMEDICA, INC.

303 SOUTH BROADWAY, SUITE 125

(Street)

TARRYTOWN

10591

(City)

(State)

(Zip)

2. Issuer Name and Ticker or Trading Symbol
PaxMedica, Inc. [ PXMD ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

X	Director	10% Owner
X	Officer (give title below)	Other (specify below)
Executive Chairman

3. Date of Earliest Transaction (Month/Day/Year)
07/26/2023

4. If Amendment, Date of Original Filed (Month/Day/Year)

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	Code	V	Amount	(A) or (D)	Price		6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
Common Stock	07/26/2023		F⁽¹⁾		6,272	D	$0.717	461,886	D
Common Stock								7,336,745	I	TardiMed Sciences, LLC⁽²⁾

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares	8. Price of Derivative Security (Instr. 5)		10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)

Explanation of Responses:

1. Shares withheld by issuer to satisfy tax withholding obligations of reporting person resulting from vesting of restricted stock units.

	/s/ Stephen D. Sheldon, Jr. Attorney-in-Fact	07/28/2023
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
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