S-8

S-8 1 ocs-20260806.htm S-8 S-8

As filed with the Securities and Exchange Commission on August 6, 2026

Registration No. 333-

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

FORM S-8

REGISTRATION STATEMENT

UNDER

THE SECURITIES ACT OF 1933

OCULIS HOLDING AG

(Exact name of Registrant as Specified in Its Charter)



Switzerland	2834	Not Applicable
(Jurisdiction of Incorporation or Organization)	(Primary Standard Industrial Classification Code Number)	(I.R.S. Employer Identification No.)

Bahnhofstrasse 20

CH-6300

Zug, Switzerland

Tel.: +41-41-711-3960

(Address, including zip code, and telephone number, including area code, of Registrant’s principal executive offices)

Stock Option and Incentive Plan Regulation 2023

(Full title of the plan)

Oculis US Inc.

One Gateway Center

300 Washington Street, Suite 700

Newton, MA 02458

Tel: +1 (617) 928-5886

(Name, address, including zip code, and telephone number, including area code, of agent for service)

Copies to:

     Divakar Gupta
Eric Blanchard
Cooley LLP
55 Hudson Yards
New York, NY 10001
+1 212 479 6000
 

     Dr. Matthias Staehelin
Dr. Vincent Reardon
VISCHER AG
Aeschenvorstadt 4 Postfach
4010 Basel, Switzerland
+41 58 211 33 00
 

    

Indicate by check mark whether the Registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company or an emerging growth company. See the definitions of “large accelerated filer,” “accelerated filer,” “smaller reporting company,” and “emerging growth company” in Rule 12b-2 of the Exchange Act.



Large accelerated filer	☒	Accelerated filer	☐

Non-accelerated filer	☐	Smaller reporting company	☐

		Emerging growth company	☐

If an emerging growth company, indicate by check mark if the Registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 7(a)(2)(B) of the Securities Act. ☐

EXPLANATORY NOTE

Oculis Holding AG, a stock corporation (Aktiengesellschaft) incorporated and existing under the laws of Switzerland (the “Company”) is filing this Registration Statement with the Securities and Exchange Commission (the “Commission”) to register an additional 197,700 ordinary shares issuable under the Company’s Stock Option and Incentive Plan Regulation 2023.

As used in this Registration Statement, unless the context otherwise requires, references to “we,” “us” and “our” refer to Oculis Holding AG.

PART I

INFORMATION REQUIRED IN THE SECTION 10(a) PROSPECTUS

The documents containing the information specified in Part I of this Registration Statement will be delivered in accordance with Form S-8 and Rule 428(d) under the Securities Act of 1933, as amended (the “Securities Act”). These documents are not required to be, and are not, filed with Commission either as part of this Registration Statement or as prospectuses or prospectus supplements pursuant to Rule 424 of the Securities Act. The documents containing the information specified in Part I will be sent or given to participants as specified by Rule 428(b)(1) under the Securities Act. These documents and the documents incorporated by reference in this Registration Statement pursuant to Item 3 of Part II of this Registration Statement, taken together, constitute a prospectus that meets the requirements of Section 10(a) of the Securities Act.

Our ordinary shares are listed on The Nasdaq Stock Market LLC under the ticker symbol “OCS” and on The Nasdaq Iceland Main Market under the ticker symbol “OCS”. Our warrants are listed on The Nasdaq Stock Market LLC under the ticker symbol “OCSAW”.


ITEM 1.	PLAN INFORMATION

Not required to be filed with this Registration Statement.


ITEM 2.	REGISTRANT INFORMATION AND EMPLOYEE PLAN ANNUAL INFORMATION

Not required to be filed with this Registration Statement.

PART II

INFORMATION REQUIRED IN THE REGISTRATION STATEMENT


ITEM 3.	INCORPORATION OF DOCUMENTS BY REFERENCE

The following document(s) filed with the Commission by the Company, pursuant to the Securities Act and the Securities Exchange Act of 1934, as amended (the “Exchange Act”), are incorporated herein by reference:

(1)

The Company’s Registration Statements on Form S-8 filed with the Commission on May 15, 2023 and June 5, 2025;

(2)

The Company’s Annual Report on Form 20-F for the year ended December 31, 2025, filed with the Commission on March 4, 2026;

(3)

The Company’s Reports on Form 6-K, filed with the Commission on March 4, 2026, May 11, 2026 (excluding Exhibit 99.3), May 14, 2026 (excluding Exhibit 99.1), June 1, 2026 and August 6, 2026 (excluding Exhibit 99.3); and

(4)

The description of the Company’s Ordinary Shares contained in Exhibit 2.5 to the Registrant’s Annual Report on Form 20-F for the year ended December 31, 2025, filed with the Commission on March 4, 2026, including any amendment or report filed for the purpose of updating such description.

In addition to the foregoing, all documents subsequently filed by the Registrant pursuant to Sections 13(a), 13(c), 14 and 15(d) of the Exchange Act, and all reports on Form 6-K, or portions thereof, subsequently filed by the Registrant which state that they are incorporated by reference herein, prior to the filing of a post-effective amendment which indicates that all securities offered hereunder have been sold or which deregisters all securities then remaining unsold, shall be deemed to be incorporated by reference herein and to be part hereof from the date of filing of such documents and reports.

Any document or any statement contained in a document or report incorporated or deemed to be incorporated by reference herein shall be deemed to be modified or superseded for purposes of this Registration Statement to the extent that a document or a statement contained in any subsequently filed document or report that is also incorporated or deemed to be incorporated by reference herein modifies or supersedes such document or statement. Any statement so modified or superseded shall not be deemed, except as so modified or superseded, to constitute a part of this Registration Statement. Subject to the foregoing, all information appearing in the Registration Statement is qualified in its entirety by the information appearing in the documents incorporated by reference.


ITEM 4.	DESCRIPTION OF SECURITIES

Not applicable.


ITEM 5.	INTERESTS OF NAMED EXPERTS AND COUNSEL

None.


ITEM 6.	INDEMNIFICATION OF DIRECTORS AND OFFICERS

Under Swiss corporate law, an indemnification by the corporation of a director or member of the executive committee in relation to potential personal liability is not effective to the extent the director or member of the executive committee

intentionally or negligently violated his or her corporate duties towards the corporation. Furthermore, the general meeting of shareholders may discharge (release) the directors and members of the executive committee from liability for their conduct to the extent the shareholders have knowledge of the relevant facts of a potential claim. Such discharge is effective only with respect to claims of the company and of those shareholders who approved the discharge or who have since acquired their shares in full knowledge of the discharge. Most violations of corporate law are regarded as violations of duties towards the corporation rather than towards the shareholders. In addition, indemnification of other controlling persons is not permitted under Swiss corporate law, including shareholders of the corporation.

Our Articles of Association provide for indemnification of the existing and former members of the board of directors or the executive committee against liabilities arising in connection with the performance of their duties in such capacity. In addition, under general principles of Swiss employment law, an employer may be required to indemnify an employee against losses and expenses incurred by such employee in the proper execution of his or her duties under the employment agreement with the employer.

We have entered into indemnification agreements with each of the members of our board of directors and executive officers, the form of which has been filed as an exhibit to our annual report on Form 20-F filed with the Securities and Exchange Commission.


ITEM 7.	EXEMPTION FROM REGISTRATION CLAIMED

Not applicable.


ITEM 8.		EXHIBITS

4.1*		Amended and Restated Articles of Association of Oculis Holding AG.
4.2		Stock Option and Incentive Plan Regulation 2023 of Oculis Holding AG (incorporated by reference to Exhibit 4.5 to our Report on Form 20-F filed on March 4, 2026).
5.1*		Opinion of Vischer AG, Swiss counsel to Oculis Holding AG, as to the validity of the Ordinary Shares being registered.
23.1*		Consent of PricewaterhouseCoopers, SA., independent registered accounting firm for Oculis Holding AG.
23.2*		Consent of Vischer AG (included as part of Exhibit 5.1).
24.1*		Power of Attorney (included on the signature page hereto).
107*		Filing Fee Table.


*	Filed herewith.


ITEM 9.	UNDERTAKINGS

(a) The undersigned Registrant hereby undertakes:

(1) To file, during any period in which offers or sales are being made, a post-effective amendment to this Registration Statement:

(i) To include any prospectus required by Section 10(a)(3) of the Securities Act;

(ii) To reflect in the prospectus any facts or events arising after the effective date of this Registration Statement (or the most recent post- effective amendment thereof) which, individually or in the aggregate, represent a fundamental change in the information set forth in this Registration Statement. Notwithstanding the foregoing, any increase or decrease in volume of securities offered (if the total dollar value of securities offered would not exceed that which was registered) and any deviation from the low or high end of the estimated maximum offering range may be reflected in the form of prospectus filed with the Commission pursuant to Rule 424(b) if, in the aggregate, the changes in volume and price represent no more than 20% change in the maximum aggregate offering price set forth in the “Calculation of Registration Fee” table in the effective registration statement;

(iii) To include any material information with respect to the plan of distribution not previously disclosed in this Registration Statement or any material change to such information in this Registration Statement;

provided, however, that paragraphs (a)(1)(i) and (a)(1)(ii) do not apply if the information required to be included in a post-effective amendment by those paragraphs is contained in reports filed with or furnished to the Commission by the Registrant pursuant to Section 13 or 15(d) of the Exchange Act that are incorporated by reference in this Registration Statement.

(2) That, for the purpose of determining any liability under the Securities Act each such post-effective amendment shall be deemed to be a new registration statement relating to the securities offered therein, and the offering of such securities at that time shall be deemed to be the initial bona fide offering thereof.

(3) To remove from registration by means of a post-effective amendment any of the securities being registered which remain unsold at the termination of the offering.

(b) The undersigned Registrant hereby undertakes that, for purposes of determining any liability under the Securities Act, each filing of the Registrant’s annual report pursuant to Section 13(a) or Section 15(d) of the Exchange Act (and, where applicable, each filing of an employee benefit plan’s annual report pursuant to Section 15(d) of the Exchange Act) that is incorporated by reference in the registration statement shall be deemed to be a new registration statement relating to the securities offered therein, and the offering of such securities at that time shall be deemed to be the initial bona fide offering thereof.

(c) Insofar as indemnification for liabilities arising under the Securities Act may be permitted to directors, officers and controlling persons of the Registrant pursuant to the foregoing provisions, or otherwise, the Registrant has been advised that in the opinion of the Commission such indemnification is against public policy as expressed in the Securities Act and is, therefore, unenforceable. In the event that a claim for indemnification against such liabilities (other than the payment by the Registrant of expenses incurred or paid by a director, officer or controlling person of the Registrant in the successful defense of any action, suit or proceeding) is asserted by such director, officer or controlling person in connection with the securities being registered, the Registrant will, unless in the opinion of its counsel the matter has been settled by controlling precedent, submit to a court of appropriate jurisdiction the question whether such indemnification by it is against public policy as expressed in the Securities Act and will be governed by the final adjudication of such issue.

SIGNATURES

Pursuant to the requirements of the Securities Act of 1933, as amended, the Registrant certifies that it has reasonable grounds to believe that it meets all of the requirements for filing on Form S-8 and has duly caused this Registration Statement to be signed on its behalf by the undersigned, thereunto duly authorized, in Switzerland, on August 6, 2026.



OCULIS HOLDING AG

By:		/s/ Riad Sherif
Name: Riad Sherif
Title: Chief Executive Officer

POWER OF ATTORNEY

Each of the undersigned individuals hereby severally constitutes and appoints each of Riad Sherif and Sylvia Cheung as the attorneys-in-fact for the undersigned, in any and all capacities, with full power of substitution, to sign on such person’s behalf, individually and in each capacity stated below, any and all amendments to this registration statement, and any subsequent registration statement filed by the Registrant pursuant to Rule 462(b) of the Securities Act, and to file or cause to be filed the same, with all exhibits thereto, and other documents in connection therewith, with the SEC, granting unto said attorneys-in-fact, and each of them, full power and authority to do and perform each and every act and thing requisite or necessary to be done in connection therewith, as fully to all intents and purposes as such person might or could do in person, hereby ratifying and confirming all that said attorneys-in-fact, and each of them, or his or her substitute or substitutes, may lawfully do or cause to be done by virtue hereof.

Pursuant to the requirements of the Securities Act of 1933, as amended, this Registration Statement has been signed by the following person in the capacities indicated and on the date indicated below.



Signature	Title	Date

/s/ Riad Sherif Riad Sherif	Chief Executive Officer (Principal Executive Officer)	August 6, 2026

/s/ Sylvia Cheung Sylvia Cheung	Chief Financial Officer (Principal Financial and Accounting Officer)	August 6, 2026

/s/ Anthony Rosenberg Anthony Rosenberg	Executive Chairman of the Board	August 6, 2026

/s/ Arshad M. Khanani, M.D. Arshad M. Khanani, M.D.	Director	August 6, 2026

/s/ Christina Ackermann Christina Ackermann	Director	August 6, 2026

/s/ Geraldine O’Keeffe Geraldine O’Keeffe	Director	August 6, 2026

/s/ Lionel Carnot Lionel Carnot	Director	August 6, 2026

/s/ Martijn Kleijwegt Martijn Kleijwegt	Director	August 6, 2026

/s/ Gregory Perry Gregory Perry	Director	August 6, 2026

      /s/ Robert K. Warner
Robert K. Warner

      Director

      August 6, 2026

SIGNATURE OF AUTHORIZED U.S. REPRESENTATIVE OF THE REGISTRANT

Pursuant to the requirements of the Securities Act of 1933, as amended, the undersigned has signed this registration statement, solely in the capacity as the duly authorized representative of the Registrant, in Boston, Massachusetts, on August 6, 2026.



OCULIS US INC

By:		/s/ Sylvia Cheung
Name: Sylvia Cheung Title: Chief Financial Officer