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    SEC Form SC 13G filed by Mersana Therapeutics Inc.

    5/17/24 8:26:06 AM ET
    $MRSN
    Biotechnology: Pharmaceutical Preparations
    Health Care
    Get the next $MRSN alert in real time by email
    SC 13G 1 tm2414799d1_sc13g.htm SC 13G

     

     

    UNITED STATES

    SECURITIES AND EXCHANGE COMMISSION

    Washington, D.C. 20549

     

    SCHEDULE 13G

     

    Under the Securities Exchange Act of 1934

    (Amendment No. )*

     

    Mersana Therapeutics, Inc.

    (Name of Issuer)

     

    Common stock, $0.0001 par value per share

    (Title of Class of Securities)

     

    59045L106

    (CUSIP Number)

     

    May 14, 2024

    (Date of Event Which Requires Filing of this Statement)

     

    Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

     

    ¨         Rule 13d-1(b)

     

    x        Rule 13d-1(c)

     

    ¨         Rule 13d-1(d)

     

    *The remainder of this cover page shall be filled out for a reporting person's initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter the disclosures provided in a prior cover page.

     

    The information required in the remainder of this cover page shall not be deemed to be "filed" for the purpose of Section 18 of the Securities Exchange Act of 1934 ("Act") or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).

     

     

     

     

     

    CUSIP No.   59045L106
    1.

    Names of Reporting Persons

    Nextech Crossover I SCSp

    2.

    Check the Appropriate Box if a Member of a Group (See Instructions)

    (a)  ¨      (b) x (1) 

    3. SEC Use Only
    4.

    Citizenship or Place of Organization

    Luxembourg

    Number of

    Shares

    Beneficially

    Owned by

    Each

    Reporting

    Person With

    5.

    Sole Voting Power

    6,248,843 shares

    6.

    Shared Voting Power

    0

    7.

    Sole Dispositive Power

    6,248,843 shares

    8.

    Shared Dispositive Power

    0

    9.

    Aggregate Amount Beneficially Owned by Each Reporting Person

    6,248,843 shares

    10. Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)    ¨
    11.

    Percent of Class Represented by Amount in Row (9)

    5.1% (2)

    12.

    Type of Reporting Person (See Instructions)

    PN

                    
    (1)This Schedule 13G is filed by Nextech Crossover I SCSP (“Nextech Crossover LP”), Nextech Crossover I GP S.à r.l. (“Nextech Crossover GP”), Ian Charoub, (“Charoub”), Costas Constantinides (“Constantinides”) and Rocco Sgobbo (“Sgobbo” and, with Nextech Crossover LP, Nextech Crossover GP, Charoub and Constantinides, collectively, the “Reporting Persons”). The Reporting Persons expressly disclaim status as a “group” for purposes of this Schedule 13G.
    (2)The percent of class was calculated based on 122,361,236 shares of Common Stock outstanding as of May 3, 2024, as reported in the Issuer’s Quarterly Report on Form 10-Q filed with the Securities and Exchange Commission (the “SEC”) on May 9, 2024.

     

    2

     

     

    CUSIP No.   59045L106
    1.

    Names of Reporting Persons

    Nextech Crossover I GP S.à r.l.

    2.

    Check the Appropriate Box if a Member of a Group (See Instructions)

    (a) ¨        (b) x (1) 

    3. SEC Use Only
    4.

    Citizenship or Place of Organization

    Luxembourg

    Number of

    Shares

    Beneficially

    Owned by

    Each

    Reporting

    Person With

    5.

    Sole Voting Power

    6,248,843 shares

    6.

    Shared Voting Power

    0

    7.

    Sole Dispositive Power

    6,248,843 shares

    8.

    Shared Dispositive Power

    0

    9.

    Aggregate Amount Beneficially Owned by Each Reporting Person

    6,248,843 shares

    10. Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)    ¨
    11.

    Percent of Class Represented by Amount in Row (9)

    5.1% (2)

    12.

    Type of Reporting Person (See Instructions)

    OO

           
    (1)This Schedule 13G is filed by the Reporting Persons. The Reporting Persons expressly disclaim status as a “group” for purposes of this Schedule 13G.
    (2)The percent of class was calculated based on 122,361,236 shares of Common Stock outstanding as of May 3, 2024, as reported in the Issuer’s Quarterly Report on Form 10-Q filed with the SEC on May 9, 2024.

     

    3

     

     

    CUSIP No.   59045L106
    1.

    Names of Reporting Persons

    Ian Charoub

    2.

    Check the Appropriate Box if a Member of a Group (See Instructions)

    (a) ¨         (b) x (1) 

    3. SEC Use Only
    4.

    Citizenship or Place of Organization

    Sweden

    Number of

    Shares

    Beneficially

    Owned by

    Each

    Reporting

    Person With

    5.

    Sole Voting Power

    0

    6.

    Shared Voting Power

    6,248,843 shares

    7.

    Sole Dispositive Power

    0

    8.

    Shared Dispositive Power

    6,248,843 shares

    9.

    Aggregate Amount Beneficially Owned by Each Reporting Person

    6,248,843 shares

    10. Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)    ¨
    11.

    Percent of Class Represented by Amount in Row (9)

    5.1% (2)

    12.

    Type of Reporting Person (See Instructions)

    IN

           
    (1)This Schedule 13G is filed by the Reporting Persons. The Reporting Persons expressly disclaim status as a “group” for purposes of this Schedule 13G.
    (2)The percent of class was calculated based on 122,361,236 shares of Common Stock outstanding as of May 3, 2024, as reported in the Issuer’s Quarterly Report on Form 10-Q filed with the SEC on May 9, 2024.

     

    4

     

     

    CUSIP No.   59045L106
    1.

    Names of Reporting Persons

    Costas Constantinides

    2.

    Check the Appropriate Box if a Member of a Group (See Instructions)

    (a) ¨        (b) x (1) 

    3. SEC Use Only
    4.

    Citizenship or Place of Organization

    Cyprus

    Number of

    Shares

    Beneficially

    Owned by

    Each

    Reporting

    Person With

    5.

    Sole Voting Power

    0

    6.

    Shared Voting Power

    6,248,843 shares

    7.

    Sole Dispositive Power

    0

    8.

    Shared Dispositive Power

    6,248,843 shares

    9.

    Aggregate Amount Beneficially Owned by Each Reporting Person

    6,248,843 shares

    10. Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)    ¨
    11.

    Percent of Class Represented by Amount in Row (9)

    5.1% (2)

    12.

    Type of Reporting Person (See Instructions)

    IN

           
    (1)This Schedule 13G is filed by the Reporting Persons. The Reporting Persons expressly disclaim status as a “group” for purposes of this Schedule 13G.
    (2)The percent of class was calculated based on 122,361,236 shares of Common Stock outstanding as of May 3, 2024, as reported in the Issuer’s Quarterly Report on Form 10-Q filed with the SEC on May 9, 2024.

     

    5

     

     

    CUSIP No.   59045L106
    1.

    Names of Reporting Persons

    Rocco Sgobbo

    2.

    Check the Appropriate Box if a Member of a Group (See Instructions)

    (a) ¨        (b) x (1) 

    3. SEC Use Only
    4.

    Citizenship or Place of Organization

    Switzerland

    Number of

    Shares

    Beneficially

    Owned by

    Each

    Reporting

    Person With

    5.

    Sole Voting Power

    0

    6.

    Shared Voting Power

    6,248,843 shares

    7.

    Sole Dispositive Power

    0

    8.

    Shared Dispositive Power

    6,248,843 shares

    9.

    Aggregate Amount Beneficially Owned by Each Reporting Person

    6,248,843 shares

    10. Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)    ¨
    11.

    Percent of Class Represented by Amount in Row (9)

    5.1% (2)

    12.

    Type of Reporting Person (See Instructions)

    IN

           
    (1)This Schedule 13G is filed by the Reporting Persons. The Reporting Persons expressly disclaim status as a “group” for purposes of this Schedule 13G.
    (2)The percent of class was calculated based on 122,361,236 shares of Common Stock outstanding as of May 3, 2024, as reported in the Issuer’s Quarterly Report on Form 10-Q filed with the SEC on May 9, 2024.

     

    6

     

     

    Item 1.
     
      (a)

    Name of Issuer

     

    Mersana Therapeutics, Inc.

      (b)

    Address of Issuer’s Principal Executive Offices

     

    840 Memorial Drive

    Cambridge, MA 02139

     
    Item 2.
     
      (a)

    Name of Person Filing

     

    Nextech Crossover I SCSp (“Nextech Crossover LP”)

    Nextech Crossover I GP S.à r.l. (“Nextech Crossover GP”)

    Ian Charoub (“Charoub”)

    Costas Constantinides (“Constantinides”)

    Rocco Sgobbo (“Sgobbo”)

      (b)

    Address of Principal Business Office or, if none, Residence

     

    8 rue Lou Hemmer

    L-1748 Luxembourg-Findel

    Grand-Duché de Luxembourg

      (c) Citizenship    
             
        Name Citizenship or Place of Organization  
        Nextech Crossover LP Luxembourg  
        Nextech Crossover GP Luxembourg  
        Charoub Sweden  
        Constantinides Cyprus  
        Sgobbo Switzerland  

      (d)

    Title of Class of Securities

     

    Common Stock, $0.0001 par value (“Common Stock”)

      (e)

    CUSIP Number

     

    59045L106

     

    Item 3. If this statement is filed pursuant to §§240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:
       
      Not applicable

     

    7

     

     

     
    Item 4. Ownership
       
    The following information regarding the aggregate number and percentage of the class of securities of the issuer identified in Item 1 is provided as of May 17, 2024:

     

    Reporting Persons  Shares
    Held
    Directly
      Sole
    Voting
    Power
      Shared
    Voting
    Power
      Sole
    Dispositive
    Power
      Shared
    Dispositive
    Power
      Beneficial
    Ownership
      Percentage
    of Class (2)
     
    Nextech Crossover LP (1)  6,248,843  6,248,843     6,248,843     6,248,843  5.1%
    Nextech Crossover GP (1)     6,248,843     6,248,843     6,248,843  5.1%
    Charoub (1)        6,248,843     6,248,843  6,248,843  5.1%
    Constantinides (1)        6,248,843     6,248,843  6,248,843  5.1%
    Sgobbo (1)        6,248,843     6,248,843  6,248,843  5.1%

     

     (1)The shares are held by Nextech Crossover LP. Nextech Crossover GP serves as the sole general partner of Nextech Crossover LP and has sole voting and investment control over the shares owned by Nextech Crossover LP and may be deemed to own beneficially the shares held by Nextech Crossover LP. Nextech Crossover GP owns no securities of the Issuer directly. Charoub, Constantinides and Sgobbo are members of the board of managers of Nextech Crossover GP and share voting and dispositive power over the shares held by Nextech Crossover LP, and may be deemed to own beneficially the shares held by Nextech Crossover LP. Charoub, Constantinides and Sgobbo own no securities of the Issuer directly.
       
     (2)The percent of class was calculated based on 122,361,236 shares of Common Stock outstanding as of May 3, 2024, as reported in the Issuer’s Quarterly Report on Form 10-Q filed with the SEC on May 9, 2024.

     

    Item 5. Ownership of Five Percent or Less of a Class
       
      If this statement is being filed to report the fact that as of the date hereof the reporting person has ceased to be the beneficial owner of more than five percent of the class of securities, check the following   ¨
     
    Item 6. Ownership of More than Five Percent on Behalf of Another Person
       
      Not applicable
     
    Item 7. Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on By the Parent Holding Company or Control Person
       
      Not applicable
     
    Item 8. Identification and Classification of Members of the Group
       
      Not applicable
     
    Item 9. Notice of Dissolution of Group
       
      Not applicable
     
    Item 10. Certification
       
      By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having such purpose or effect.

     

    8

     

     

    Signature

     

    After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

     

    Dated: May 17, 2024  
       
    Nextech Crossover I SCSp  
       
    By: Nextech Crossover I GP S.à r.l.  
    its General Partner  
       
    By: /s/ Ian Charoub  
      Name: Ian Charoub  
      Title: Manager  
       
    By: /s/ Costas Constantinides  
      Name: Costas Constantinides  
      Title: Manager  
       
    Nextech Crossover I GP S.à r.l.  
       
    By: /s/ Ian Charoub  
        Name: Ian Charoub  
        Title: Manager  
       
    By: /s/ Costas Constantinides  
        Name: Costas Constantinides  
        Title: Manager  
       
    /s/ Ian Charoub  
    Ian Charoub  
       
    /s/ Costas Constantinides  
    Costas Constantinides  
       
    /s/ Rocco Sgobbo  
    Rocco Sgobbo  

     

      ATTENTION  
    Intentional misstatements or omissions of fact constitute Federal Criminal Violations (See 18 U.S.C. 1001).

     

    9

     

     

    Exhibit(s):

     

    AJoint Filing Agreement

     

    10

     

     

    EXHIBIT A

     

    JOINT FILING AGREEMENT

     

    We, the undersigned, hereby express our agreement that the attached Schedule 13G (or any amendments thereto) relating to the Common Stock of Mersana Therapeutics, Inc. is filed on behalf of each of us.

     

    Dated: May 17, 2024  
       
    Nextech Crossover I SCSp  
       
    By: Nextech Crossover I GP S.à r.l.  
    its General Partner  
       
    By: /s/ Ian Charoub  
      Name: Ian Charoub  
      Title: Manager  
       
    By: /s/ Costas Constantinides  
      Name: Costas Constantinides  
      Title: Manager  
       
    Nextech Crossover I GP S.à r.l.  
       
    By: /s/ Ian Charoub  
        Name: Ian Charoub  
        Title: Manager  
       
    By: /s/ Costas Constantinides  
        Name: Costas Constantinides  
        Title: Manager  
       
    /s/ Ian Charoub  
    Ian Charoub  
       
    /s/ Costas Constantinides  
    Costas Constantinides  
       
    /s/ Rocco Sgobbo  
    Rocco Sgobbo  

     

     

     

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      Updated clinical data from Emi-Le Phase 1 dose escalation and backfill cohorts presented today at ESMO Breast Cancer 2025 ORR increased to 31% across tumor types among evaluable patients with B7-H4 high tumors receiving intermediate dosesEncouraging preliminary time-to-event data in triple-negative breast cancer (TNBC) Second, higher dose recently selected for expansion in post-topoisomerase-1 inhibitor ADC (post-topo-1) TNBC; patient enrollment advancing in both dose expansion cohorts Plan to report initial clinical data from expansion in second half of 2025Conference call today at 8:00 a.m. ET CAMBRIDGE, Mass., May 15, 2025 (GLOBE NEWSWIRE) -- Mersana Therapeutics, Inc. (NASDAQ:MRSN), a

      5/15/25 7:00:40 AM ET
      $MRSN
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Mersana Therapeutics Announces Strategic Restructuring and Reprioritization Plan Focused on Advancing Emi-Le in Triple-Negative Breast Cancer

      Cost-saving initiatives expected to extend company's cash runway and support current operating plan commitments into mid-2026 Company to host conference call at 8:00 a.m. ET on May 15 to discuss business updates and first quarter 2025 financial results CAMBRIDGE, Mass., May 06, 2025 (GLOBE NEWSWIRE) -- Mersana Therapeutics, Inc. (NASDAQ:MRSN), a clinical-stage biopharmaceutical company focused on developing a pipeline of antibody-drug conjugates (ADCs) targeting cancers in areas of high unmet medical need, today announced the implementation of a strategic restructuring and reprioritization plan aimed at extending the company's cash runway and furthering the development of emiltatug ledad

      5/6/25 7:00:51 AM ET
      $MRSN
      Biotechnology: Pharmaceutical Preparations
      Health Care

    $MRSN
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    • Amendment: SEC Form SC 13D/A filed by Mersana Therapeutics Inc.

      SC 13D/A - Mersana Therapeutics, Inc. (0001442836) (Subject)

      11/15/24 4:45:57 PM ET
      $MRSN
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Amendment: SEC Form SC 13G/A filed by Mersana Therapeutics Inc.

      SC 13G/A - Mersana Therapeutics, Inc. (0001442836) (Subject)

      11/14/24 5:45:55 PM ET
      $MRSN
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Amendment: SEC Form SC 13G/A filed by Mersana Therapeutics Inc.

      SC 13G/A - Mersana Therapeutics, Inc. (0001442836) (Subject)

      11/14/24 6:01:51 AM ET
      $MRSN
      Biotechnology: Pharmaceutical Preparations
      Health Care