Pre-market movers - September 17, 2026

Here is how US equities are shaping up pre-market on September 17, 2026. The names below show the widest percentage moves against yesterday's close, giving a quick read on where retail and institutional attention is concentrating before the opening bell.

Delixy Holdings Limited (DLXY) leads pre-market gainers, climbing +451.81% to $2.29. MEDS at +274.69% and SNYR at +233.41% round out the early movers. The remaining 7 names in the top 10 are up an average of 81.69% heading into the open.

Xenetic Biosciences Inc. (XBIO) leads pre-market losers, falling +48.71% to $2.19. CUPR at -45.39% and EDBLW at -45.12% round out the early movers. The remaining 7 names in the top 10 are down an average of 34.32% heading into the open.

Pre-market action does not always carry into the regular session - gaps often fade once liquidity returns - but outsized moves here frequently trace back to overnight filings, earnings, analyst actions, or macro headlines worth checking on each ticker's wire.