ALX Oncology Holdings Inc., a clinical-stage immuno-oncology company, focuses on developing therapies for patients fighting cancer. Its lead product candidate is ALX148, a CD47 blocking therapeutic that is in Phase 1b/2 clinical trial used for the treatment of myelodysplastic syndromes; and for the treatment of acute myeloid leukemia and non-Hodgkin's lymphoma, as well as a range of solid tumor indications, including head and neck squamous cell; human epidermal growth factor receptor 2 (HER2) positive gastric/gastroesophageal junction carcinoma; and HER2-expressing breast cancer. The company's pre-clinical products include SIRPa TRAAC that offers ways to engage the innate and adaptive immune response to cancer. ALX Oncology Holdings Inc. has a collaboration agreement with Merck for a Phase 2 trial evaluating ALX148 in combination with pembrolizumab with and without chemotherapy in patients with head and neck cancer; Zymeworks on a Phase 1 trial evaluating ALX148 with the HER2-targeting bispecific antibody zanidatamab in patients with advanced HER2-expressing breast cancer and other solid tumors; and Tallac Therapeutics for the development, manufacturing and commercialization of a novel class of cancer immunotherapeutics. It also has a license agreement with Selexis SA and Crystal Bioscience, Inc. The company was incorporated in 2015 and is based in Burlingame, California.
IPO Year: 2020
Exchange: NASDAQ
Website: alxoncology.com
| Date | Price Target | Rating | Analyst |
|---|---|---|---|
| 3/6/2025 | $2.00 → $3.00 | Hold → Buy | Jefferies |
| 12/19/2024 | $12.00 → $2.00 | Buy → Hold | Jefferies |
| 3/8/2024 | $10.00 → $14.00 | Buy → Hold | Stifel |
| 12/8/2023 | $8.00 → $18.00 | Hold → Buy | Jefferies |
| 3/1/2022 | $60.00 → $36.00 | Buy | Stifel |
| 12/22/2021 | $65.00 → $25.00 | Buy → Hold | Jefferies |
| 9/30/2021 | $106.00 | Buy | Stifel |