GPCR - SEC Form 4 insider transactions

COO & GC Lang Matthew was granted 184,614 units of Ordinary Shares (SEC Form 4)

SEC Form 4 filed by Fmr Llc

SEC Form 4 filed by Hall Ashley

SEC Form 4 filed by Lin Xichen

SEC Form 4 filed by Ma Yingli

SEC Form 4 filed by Coll Crespo Blas

SEC Form 4 filed by Yoon Jun

SEC Form 4 filed by Stevens Raymond C

CHIEF TECHNOLOGY OFFICER Ma Yingli covered exercise/tax liability with 11,313 units of Ordinary Shares, decreasing direct ownership by 10% to 107,391 units (SEC Form 4)

CHIEF MEDICAL OFFICER Coll Crespo Blas covered exercise/tax liability with 11,826 units of Ordinary Shares, decreasing direct ownership by 5% to 204,981 units (SEC Form 4)

CHIEF EXECUTIVE OFFICER Stevens Raymond C covered exercise/tax liability with 53,454 units of Ordinary Shares, decreasing direct ownership by 4% to 1,141,376 units (SEC Form 4)

CHIEF SCIENTIFIC OFFICER Lin Xichen covered exercise/tax liability with 18,735 units of Ordinary Shares, decreasing direct ownership by 9% to 185,592 units (SEC Form 4)

Chief Development Officer Hall Ashley covered exercise/tax liability with 4,836 units of Ordinary Shares, decreasing direct ownership by 4% to 107,481 units (SEC Form 4)

CHIEF FINANCIAL OFFICER Yoon Jun covered exercise/tax liability with 22,305 units of Ordinary Shares, decreasing direct ownership by 2% to 1,297,571 units (SEC Form 4)

SEC Form 4 filed by See Remark 1 Fmr Llc

SEC Form 4 filed by See Remark 1 Fmr Llc

CHIEF MEDICAL OFFICER Coll Crespo Blas covered exercise/tax liability with 8,106 units of Ordinary Shares, decreasing direct ownership by 4% to 216,807 units (SEC Form 4)

Chief Development Officer Hall Ashley covered exercise/tax liability with 6,021 units of Ordinary Shares, decreasing direct ownership by 5% to 112,317 units (SEC Form 4)

CHIEF SCIENTIFIC OFFICER Lin Xichen covered exercise/tax liability with 12,846 units of Ordinary Shares, decreasing direct ownership by 6% to 204,327 units (SEC Form 4)

CHIEF TECHNOLOGY OFFICER Ma Yingli covered exercise/tax liability with 4,470 units of Ordinary Shares, decreasing direct ownership by 4% to 118,704 units (SEC Form 4)

SEC Form 4 filed by See Remark 1 Fmr Llc

CHIEF TECHNOLOGY OFFICER Ma Yingli covered exercise/tax liability with 1,824 units of Ordinary Shares and was granted 24,459 units of Ordinary Shares, increasing direct ownership by 23% to 123,174 units (SEC Form 4)

CHIEF MEDICAL OFFICER Coll Crespo Blas was granted 7,992 units of Ordinary Shares and covered exercise/tax liability with 2,667 units of Ordinary Shares, increasing direct ownership by 2% to 224,913 units (SEC Form 4)

CHIEF SCIENTIFIC OFFICER Lin Xichen covered exercise/tax liability with 6,441 units of Ordinary Shares and was granted 57,078 units of Ordinary Shares, increasing direct ownership by 30% to 217,173 units (SEC Form 4)

CHIEF FINANCIAL OFFICER Yoon Jun covered exercise/tax liability with 13,029 units of Ordinary Shares and was granted 39,606 units of Ordinary Shares, increasing direct ownership by 2% to 1,319,876 units (SEC Form 4)

CHIEF EXECUTIVE OFFICER Stevens Raymond C covered exercise/tax liability with 28,545 units of Ordinary Shares and was granted 89,697 units of Ordinary Shares, increasing direct ownership by 5% to 1,194,830 units (SEC Form 4)

SEC Form 4 filed by Director Love Ted W

SEC Form 4 filed by Director Russell Angus C.

SEC Form 4 filed by Director Waldstreicher Joanne

SEC Form 4 filed by Director Tetlow Sharon

SEC Form 4 filed by Director Dobmeier Eric

SEC Form 4 filed by Director Welch Daniel G

Chief Development Officer Hall Ashley was granted 51,048 units of Ordinary Shares, increasing direct ownership by 76% to 118,338 units (SEC Form 4)

CHIEF TECHNOLOGY OFFICER Ma Yingli was granted 63,810 units of Ordinary Shares, increasing direct ownership by 174% to 100,539 units (SEC Form 4)

Chief Medical Officer Coll Crespo Blas was granted 116,988 units of Ordinary Shares, increasing direct ownership by 114% to 219,588 units (SEC Form 4)

CHIEF EXECUTIVE OFFICER Stevens Raymond C was granted 340,332 units of Ordinary Shares, increasing direct ownership by 43% to 1,133,678 units (SEC Form 4)

CHIEF SCIENTIFIC OFFICER Lin Xichen was granted 80,829 units of Ordinary Shares, increasing direct ownership by 94% to 166,536 units (SEC Form 4)

CHIEF FINANCIAL OFFICER Yoon Jun was granted 170,166 units of Ordinary Shares, increasing direct ownership by 15% to 1,293,299 units (SEC Form 4)

SEC Form 4 filed by See Remark 1 Fmr Llc

Chief Development Officer Hall Ashley was granted 67,290 units of Ordinary Shares (SEC Form 4)

Chief Medical Officer Coll Crespo Blas was granted 90,600 units of Ordinary Shares, increasing direct ownership by 755% to 102,600 units (SEC Form 4)

SEC Form 4 filed by Director Russell Angus C.

SEC Form 4 filed by Director Dobmeier Eric

SEC Form 4 filed by Director Welch Daniel G

SEC Form 4 filed by Director Waldstreicher Joanne

SEC Form 4 filed by Director Love Ted W

SEC Form 4 filed by Director Tetlow Sharon

CHIEF EXECUTIVE OFFICER Stevens Raymond C exercised 150,000 units of Ordinary Shares at a strike of $0.42, increasing direct ownership by 23% to 793,346 units (SEC Form 4)

CHIEF EXECUTIVE OFFICER Stevens Raymond C decreased direct ownership by 46% to 643,346 units (SEC Form 4)

Lin Xichen exercised 106,200 units of Ordinary Shares at a strike of $0.34 (SEC Form 4)

SEC Form 4 filed by Fmr Llc

SEC Form 4 filed by Lin Xichen (Amendment)

SEC Form 4 filed by Bach Mark Allen (Amendment)

SEC Form 4 filed by Ma Yingli (Amendment)

SEC Form 4 filed by Yoon Jun (Amendment)

SEC Form 4 filed by Stevens Raymond C (Amendment)

Lin Xichen was granted 85,707 units of Ordinary Shares (SEC Form 4)

Ma Yingli was granted 36,729 units of Ordinary Shares (SEC Form 4)

Bach Mark Allen was granted 26,235 units of Ordinary Shares (SEC Form 4)

Yoon Jun was granted 59,469 units of Ordinary Shares, increasing direct ownership by 6% to 1,123,133 units (SEC Form 4)