IONS - SEC Form 4 insider transactions

SEC Form 4 filed by Director Reikes Peter N

SEC Form 4 filed by Director Hantson Ludwig

Director Herman Joan E converted options into 5,220 shares, increasing direct ownership by 11% to 51,306 units (SEC Form 4)

Director Berthelsen Spencer R converted options into 5,220 shares, increasing direct ownership by 3% to 161,233 units (SEC Form 4)

EVP, Chief Scientific Officer Bennett C Frank sold $1,744,623 worth of shares (20,536 units at $84.95) as part of a pre-agreed trading plan and acquired 15,000 shares as part of a pre-agreed trading plan, decreasing direct ownership by 7% to 75,018 units (SEC Form 4)

Director Diaz Allene M. sold $863,637 worth of shares (10,111 units at $85.42) as part of a pre-agreed trading plan and exercised 10,111 shares at a strike of $47.11 (SEC Form 4)

EVP, Chief Development Officer Kordasiewicz Holly B. sold $30,517 worth of shares (362 units at $84.30) as part of a pre-agreed trading plan, decreasing direct ownership by 2% to 22,096 units (SEC Form 4)

SEC Form 4 filed by Director Yang Michael J.

SEC Form 4 filed by Director Loscalzo Joseph

SEC Form 4 filed by Director Herman Joan E

Director Klein Joseph Iii exercised 11,518 shares at a strike of $39.94 and sold $910,416 worth of shares (11,518 units at $79.04) as part of a pre-agreed trading plan (SEC Form 4)

SEC Form 4 filed by Director Hayden Michael R

SEC Form 4 filed by Director Diaz Allene M.

SEC Form 4 filed by Director Berthelsen Spencer R

EVP, Chief Business Officer Baroldi Joseph exercised 5,635 shares at a strike of $49.19 and sold $451,699 worth of shares (5,635 units at $80.16) as part of a pre-agreed trading plan (SEC Form 4)

EVP CLO & General Counsel O'Neil Patrick R. sold $245,520 worth of shares (3,069 units at $80.00) as part of a pre-agreed trading plan, decreasing direct ownership by 5% to 61,470 units (SEC Form 4)

EVP, Chf Clinical Develop Ofcr Schneider Eugene exercised 26,000 shares at a strike of $60.89 and sold $2,107,196 worth of shares (26,000 units at $81.05) as part of a pre-agreed trading plan (SEC Form 4)

Chief Executive Officer Monia Brett P exercised 85,637 shares at a strike of $46.72 and sold $6,825,524 worth of shares (85,637 units at $79.70) as part of a pre-agreed trading plan (SEC Form 4)

EVP Research Swayze Eric sold $839,492 worth of shares (10,602 units at $79.18) as part of a pre-agreed trading plan, decreasing direct ownership by 33% to 21,759 units (SEC Form 4)

EVP, Chief Development Officer Kordasiewicz Holly B. exercised 60,846 shares at a strike of $53.97 and sold $4,466,428 worth of shares (60,846 units at $73.41) as part of a pre-agreed trading plan (SEC Form 4)

Director Berthelsen Spencer R exercised 8,000 shares at a strike of $24.42 and sold $587,920 worth of shares (8,000 units at $73.49) as part of a pre-agreed trading plan (SEC Form 4)

SEC Form 4 filed by Director Reikes Peter N

SEC Form 4 filed by Director Hantson Ludwig

Director Berthelsen Spencer R exercised 8,000 shares at a strike of $24.42 and sold $605,360 worth of shares (8,000 units at $75.67) as part of a pre-agreed trading plan (SEC Form 4)

Chief Executive Officer Monia Brett P exercised 4,536 shares at a strike of $32.60 and sold $356,012 worth of shares (4,536 units at $78.49) as part of a pre-agreed trading plan (SEC Form 4)

Director Loscalzo Joseph exercised 77,289 shares at a strike of $48.74 and sold $5,801,226 worth of shares (77,289 units at $75.06) as part of a pre-agreed trading plan (SEC Form 4)

Director Klein Joseph Iii exercised 10,111 shares at a strike of $47.11 and sold $743,238 worth of shares (10,111 units at $73.51) as part of a pre-agreed trading plan (SEC Form 4)

EVP, Chief Business Officer Baroldi Joseph sold $116,727 worth of shares (1,626 units at $71.79) as part of a pre-agreed trading plan, decreasing direct ownership by 3% to 44,909 units (SEC Form 4)

SEC Form 4 filed by Jenne Kyle

SEC Form 4 filed by Parshall B Lynne

SEC Form 4 filed by Birchler Brian

SEC Form 4 filed by Baroldi Joseph

SEC Form 4 filed by Klein Joseph Iii

SEC Form 4 filed by Devers Shannon L.

SEC Form 4 filed by Schneider Eugene

SEC Form 4 filed by Ionis Pharmaceuticals Inc.

Chief Executive Officer Monia Brett P sold $12,114,155 worth of shares (160,773 units at $75.35) and exercised 148,454 shares at a strike of $60.89, decreasing direct ownership by 5% to 242,662 units (SEC Form 4)

SEC Form 4 filed by Ionis Pharmaceuticals Inc.

SEC Form 4 filed by Ionis Pharmaceuticals Inc.

Director Klein Joseph Iii exercised 16,000 shares at a strike of $40.76 and sold $1,696,181 worth of shares (21,332 units at $79.51), decreasing direct ownership by 33% to 11,014 units (SEC Form 4)

Director Loscalzo Joseph exercised 1,032 shares at a strike of $38.06 and sold $82,833 worth of shares (1,032 units at $80.26) (SEC Form 4)

Director Diaz Allene M. exercised 40,321 shares at a strike of $39.72 and sold $4,354,428 worth of shares (54,878 units at $79.35), decreasing direct ownership by 79% to 3,811 units (SEC Form 4)

EVP, Chief Human Resources Ofc Devers Shannon L. exercised 20,106 shares at a strike of $35.97 and sold $1,596,433 worth of shares (20,106 units at $79.40) (SEC Form 4)

EVP, Chief Scientific Officer Bennett C Frank exercised 65,089 shares at a strike of $53.73 and sold $6,741,669 worth of shares (85,089 units at $79.23), decreasing direct ownership by 20% to 80,554 units (SEC Form 4)

EVP, Chief Business Officer Baroldi Joseph sold $530,987 worth of shares (6,659 units at $79.74) and exercised 2,138 shares at a strike of $44.57, decreasing direct ownership by 9% to 41,317 units (SEC Form 4)

EVP Research Swayze Eric acquired $12,510 worth of shares (256 units at $48.87), increasing direct ownership by 0.80% to 32,361 units (SEC Form 4)

EVP CLO & General Counsel O'Neil Patrick R. acquired $18,374 worth of shares (376 units at $48.87), increasing direct ownership by 0.52% to 72,359 units (SEC Form 4)

Chief Executive Officer Monia Brett P acquired $23,651 worth of shares (484 units at $48.87), increasing direct ownership by 0.19% to 254,981 units (SEC Form 4)

EVP, Corp and Development Ops Birchler Brian acquired $17,152 worth of shares (351 units at $48.87), increasing direct ownership by 0.53% to 66,598 units (SEC Form 4)

EVP, Chief Scientific Officer Bennett C Frank acquired $12,754 worth of shares (261 units at $48.87), increasing direct ownership by 0.26% to 100,554 units (SEC Form 4)

Amendment: EVP, Chief Scientific Officer Bennett C Frank disposed of 0 shares (SEC Form 4)

EVP Research Swayze Eric sold $1,278,914 worth of shares (15,642 units at $81.76), decreasing direct ownership by 33% to 32,105 units (SEC Form 4)

Director Parshall B Lynne sold $413,588 worth of shares (5,000 units at $82.72), decreasing direct ownership by 8% to 56,344 units (SEC Form 4)

Chief Executive Officer Monia Brett P sold $2,524,820 worth of shares (29,430 units at $85.79), decreasing direct ownership by 10% to 254,497 units (SEC Form 4)

EVP, Chief Scientific Officer Bennett C Frank sold $7,056,216 worth of shares (85,089 units at $82.93) and exercised 65,089 shares at a strike of $53.73, decreasing direct ownership by 20% to 80,293 units (SEC Form 4)

EVP Research Swayze Eric was granted 11,991 shares and sold $512,446 worth of shares (6,179 units at $82.93), increasing direct ownership by 14% to 47,747 units (SEC Form 4)

EVP CLO & General Counsel O'Neil Patrick R. was granted 11,991 shares and sold $516,153 worth of shares (6,179 units at $83.53), increasing direct ownership by 9% to 71,983 units (SEC Form 4)

EVP, Chf Clinical Develop Ofcr Schneider Eugene was granted 11,991 shares and sold $515,630 worth of shares (6,179 units at $83.45), increasing direct ownership by 9% to 69,702 units (SEC Form 4)

Chief Executive Officer Monia Brett P was granted 122,214 shares and sold $5,208,979 worth of shares (62,970 units at $82.72), increasing direct ownership by 26% to 283,927 units (SEC Form 4)

EVP, Finance & CFO Hougen Elizabeth L was granted 13,562 shares and sold $581,702 worth of shares (6,988 units at $83.24), increasing direct ownership by 5% to 132,881 units (SEC Form 4)