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    Protagonist Therapeutics Inc.

    Subscribe to $PTGX
    $PTGX
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Protagonist Therapeutics, Inc., a clinical-stage biopharmaceutical company, discovers and develops peptide-based therapeutic drugs to address unmet medical needs. It is developing PTG-300, an injectable hepcidin mimetic that is in Phase II clinical trial for the treatment of patients with polycythemia vera and hereditary hemochromatosis, as well as for the treatment of other blood disorders; PTG-200, an oral, interleukin-23 receptor specific antagonist peptide, which is in phase II clinical trial for the treatment of moderate-to-severe Crohn's disease; and PN-943, an oral, alpha-4-beta-7 specific integrin antagonist that is in Phase II clinical trial for treating inflammatory bowel disease (IBD). The company has a license and collaboration agreement with Janssen Biotech, Inc. for the development, manufacture, and commercialization of PTG-200 for the treatment of Crohn's disease and ulcerative colitis; and PN-235 and PN-232 oral interleukin-23 receptor antagonist candidates for IBD and non-IBD indications. Protagonist Therapeutics, Inc. was incorporated in 2006 and is headquartered in Newark, California.

    IPO Year: 2016

    Exchange: NASDAQ

    Website: protagonist-inc.com

    Recent Analyst Ratings for Protagonist Therapeutics Inc.

    DatePrice TargetRatingAnalyst
    6/17/2025$72.00Buy
    Citigroup
    12/6/2024$47.00Neutral
    Goldman
    12/6/2024$62.00Outperform
    BMO Capital Markets
    11/5/2024$58.00Outperform
    Wedbush
    9/24/2024$65.00Buy
    TD Cowen
    9/9/2024$60.00Buy
    Truist
    10/30/2023$32.00Overweight
    CapitalOne
    5/25/2023$30.00 → $40.00Buy
    Jefferies
    8/25/2022$21.00Mkt Outperform
    JMP Securities
    2/11/2022$55.00Buy
    BTIG
    See more ratings

    Protagonist Therapeutics Inc. Insider Trading

    Insider transactions reveal critical sentiment about the company from key stakeholders. See them live in this feed.

    See more
    • President and CEO Patel Dinesh V Ph D gifted 1,355 shares, decreasing direct ownership by 0.24% to 562,905 units (SEC Form 4)

      4 - Protagonist Therapeutics, Inc (0001377121) (Issuer)

      6/17/25 4:01:12 PM ET
      $PTGX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Chief Medical Officer Molina Arturo Md exercised 20,000 shares at a strike of $8.04 and sold $1,125,400 worth of shares (20,000 units at $56.27) (SEC Form 4)

      4 - Protagonist Therapeutics, Inc (0001377121) (Issuer)

      6/11/25 5:40:40 PM ET
      $PTGX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Director Selick Harold E exercised 10,725 shares at a strike of $1.16, increasing direct ownership by 32% to 43,851 units (SEC Form 4)

      4 - Protagonist Therapeutics, Inc (0001377121) (Issuer)

      4/30/25 4:45:59 PM ET
      $PTGX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Chief Financial Officer Ali Asif sold $80,776 worth of shares (1,756 units at $46.00), decreasing direct ownership by 3% to 61,065 units (SEC Form 4)

      4 - Protagonist Therapeutics, Inc (0001377121) (Issuer)

      4/23/25 4:30:15 PM ET
      $PTGX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Director Waddill William D. sold $217,000 worth of shares (4,000 units at $54.25), decreasing direct ownership by 23% to 13,130 units (SEC Form 4)

      4 - Protagonist Therapeutics, Inc (0001377121) (Issuer)

      3/19/25 4:01:12 PM ET
      $PTGX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Chief Medical Officer Molina Arturo Md exercised 30,514 shares at a strike of $24.48 and sold $1,700,850 worth of shares (30,514 units at $55.74) (SEC Form 4)

      4 - Protagonist Therapeutics, Inc (0001377121) (Issuer)

      3/14/25 6:21:44 PM ET
      $PTGX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Chief Financial Officer Ali Asif exercised 24,903 shares at a strike of $14.90 and sold $1,462,553 worth of shares (24,903 units at $58.73) (SEC Form 4)

      4 - Protagonist Therapeutics, Inc (0001377121) (Issuer)

      3/14/25 6:20:46 PM ET
      $PTGX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • President and CEO Patel Dinesh V Ph D exercised 24,000 shares at a strike of $4.21, increasing direct ownership by 4% to 564,260 units (SEC Form 4)

      4 - Protagonist Therapeutics, Inc (0001377121) (Issuer)

      3/5/25 8:02:40 PM ET
      $PTGX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • President and CEO Patel Dinesh V Ph D sold $204,607 worth of shares (5,359 units at $38.18), decreasing direct ownership by 0.98% to 540,260 units (SEC Form 4)

      4 - Protagonist Therapeutics, Inc (0001377121) (Issuer)

      2/20/25 5:25:23 PM ET
      $PTGX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Chief Medical Officer Molina Arturo Md sold 3,640 shares, decreasing direct ownership by 4% to 83,892 units (SEC Form 4)

      4 - Protagonist Therapeutics, Inc (0001377121) (Issuer)

      1/17/25 5:47:00 PM ET
      $PTGX
      Biotechnology: Pharmaceutical Preparations
      Health Care

    Protagonist Therapeutics Inc. Analyst Ratings

    Analyst ratings in real time. Analyst ratings have a very high impact on the underlying stock. See them live in this feed.

    See more
    • Citigroup initiated coverage on Protagonist Therapeutics with a new price target

      Citigroup initiated coverage of Protagonist Therapeutics with a rating of Buy and set a new price target of $72.00

      6/17/25 7:50:36 AM ET
      $PTGX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Goldman initiated coverage on Protagonist Therapeutics with a new price target

      Goldman initiated coverage of Protagonist Therapeutics with a rating of Neutral and set a new price target of $47.00

      12/6/24 8:23:16 AM ET
      $PTGX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • BMO Capital Markets initiated coverage on Protagonist Therapeutics with a new price target

      BMO Capital Markets initiated coverage of Protagonist Therapeutics with a rating of Outperform and set a new price target of $62.00

      12/6/24 8:11:17 AM ET
      $PTGX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Wedbush initiated coverage on Protagonist Therapeutics with a new price target

      Wedbush initiated coverage of Protagonist Therapeutics with a rating of Outperform and set a new price target of $58.00

      11/5/24 6:25:30 AM ET
      $PTGX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • TD Cowen initiated coverage on Protagonist Therapeutics with a new price target

      TD Cowen initiated coverage of Protagonist Therapeutics with a rating of Buy and set a new price target of $65.00

      9/24/24 8:23:35 AM ET
      $PTGX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Truist initiated coverage on Protagonist Therapeutics with a new price target

      Truist initiated coverage of Protagonist Therapeutics with a rating of Buy and set a new price target of $60.00

      9/9/24 7:43:18 AM ET
      $PTGX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • CapitalOne initiated coverage on Protagonist Therapeutics with a new price target

      CapitalOne initiated coverage of Protagonist Therapeutics with a rating of Overweight and set a new price target of $32.00

      10/30/23 7:46:31 AM ET
      $PTGX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Jefferies resumed coverage on Protagonist Therapeutics with a new price target

      Jefferies resumed coverage of Protagonist Therapeutics with a rating of Buy and set a new price target of $40.00 from $30.00 previously

      5/25/23 7:30:36 AM ET
      $PTGX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • JMP Securities initiated coverage on Protagonist Therapeutics with a new price target

      JMP Securities initiated coverage of Protagonist Therapeutics with a rating of Mkt Outperform and set a new price target of $21.00

      8/25/22 7:41:59 AM ET
      $PTGX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • BTIG initiated coverage on Protagonist Therapeutics with a new price target

      BTIG initiated coverage of Protagonist Therapeutics with a rating of Buy and set a new price target of $55.00

      2/11/22 4:50:09 AM ET
      $PTGX
      Biotechnology: Pharmaceutical Preparations
      Health Care

    Protagonist Therapeutics Inc. SEC Filings

    See more
    • SEC Form SCHEDULE 13G filed by Protagonist Therapeutics Inc.

      SCHEDULE 13G - Protagonist Therapeutics, Inc (0001377121) (Subject)

      6/16/25 5:30:24 PM ET
      $PTGX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form SCHEDULE 13G filed by Protagonist Therapeutics Inc.

      SCHEDULE 13G - Protagonist Therapeutics, Inc (0001377121) (Subject)

      5/13/25 12:10:05 PM ET
      $PTGX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form 10-Q filed by Protagonist Therapeutics Inc.

      10-Q - Protagonist Therapeutics, Inc (0001377121) (Filer)

      5/6/25 5:04:48 PM ET
      $PTGX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Protagonist Therapeutics Inc. filed SEC Form 8-K: Results of Operations and Financial Condition, Financial Statements and Exhibits

      8-K - Protagonist Therapeutics, Inc (0001377121) (Filer)

      5/6/25 4:27:37 PM ET
      $PTGX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form DEFA14A filed by Protagonist Therapeutics Inc.

      DEFA14A - Protagonist Therapeutics, Inc (0001377121) (Filer)

      4/29/25 4:08:16 PM ET
      $PTGX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form DEF 14A filed by Protagonist Therapeutics Inc.

      DEF 14A - Protagonist Therapeutics, Inc (0001377121) (Filer)

      4/29/25 4:05:58 PM ET
      $PTGX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Protagonist Therapeutics Inc. filed SEC Form 8-K: Other Events

      8-K - Protagonist Therapeutics, Inc (0001377121) (Filer)

      3/20/25 4:12:09 PM ET
      $PTGX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form 144 filed by Protagonist Therapeutics Inc.

      144 - Protagonist Therapeutics, Inc (0001377121) (Subject)

      3/17/25 4:30:49 PM ET
      $PTGX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Amendment: Protagonist Therapeutics Inc. filed SEC Form 8-K: Other Events, Financial Statements and Exhibits

      8-K/A - Protagonist Therapeutics, Inc (0001377121) (Filer)

      3/11/25 5:17:03 PM ET
      $PTGX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Protagonist Therapeutics Inc. filed SEC Form 8-K: Other Events, Financial Statements and Exhibits

      8-K - Protagonist Therapeutics, Inc (0001377121) (Filer)

      3/10/25 8:17:57 AM ET
      $PTGX
      Biotechnology: Pharmaceutical Preparations
      Health Care