SOPH - SEC Form 4 insider transactions

Executive Chairman Camblong Jurgi sold $138,412 worth of Ordinary Shares (20,000 units at $6.92) as part of a pre-agreed trading plan, decreasing direct ownership by 0.57% to 3,472,822 units (SEC Form 4)

Chief Scientific Officer Xu Zhenyu sold $69,168 worth of Ordinary Shares (10,000 units at $6.92) as part of a pre-agreed trading plan, decreasing direct ownership by 2% to 600,887 units (SEC Form 4)

Chief Technology Officer Verma Abhimanyu sold $34,772 worth of Ordinary Shares (5,000 units at $6.95) as part of a pre-agreed trading plan, decreasing direct ownership by 3% to 187,171 units (SEC Form 4)

Chief Medical Officer Menu Philippe sold $28,306 worth of Ordinary Shares (5,000 units at $5.66) as part of a pre-agreed trading plan, decreasing direct ownership by 2% to 223,387 units (SEC Form 4)

Executive Chairman Camblong Jurgi sold $286,099 worth of Ordinary Shares (44,381 units at $6.45) as part of a pre-agreed trading plan and exercised 4,581 units of Ordinary Shares at a strike of $3.16, decreasing direct ownership by 1% to 3,492,822 units (SEC Form 4)

Chief Scientific Officer Xu Zhenyu sold $22,819 worth of Ordinary Shares (4,000 units at $5.70) as part of a pre-agreed trading plan, decreasing direct ownership by 0.65% to 610,887 units (SEC Form 4)

Chief Medical Officer Menu Philippe sold $28,505 worth of Ordinary Shares (5,000 units at $5.70) as part of a pre-agreed trading plan, decreasing direct ownership by 2% to 228,387 units (SEC Form 4)

Executive Chairman Camblong Jurgi sold $47,791 worth of Ordinary Shares (8,500 units at $5.62) as part of a pre-agreed trading plan, decreasing direct ownership by 0.24% to 3,532,622 units (SEC Form 4)

Executive Chairman Camblong Jurgi sold $93,327 worth of Ordinary Shares (17,685 units at $5.28) as part of a pre-agreed trading plan, decreasing direct ownership by 0.50% to 3,541,122 units (SEC Form 4) to satisfy tax liability

Chief Financial Officer Cardoza George sold $8,419 worth of Ordinary Shares (1,592 units at $5.29) as part of a pre-agreed trading plan, decreasing direct ownership by 0.51% to 309,092 units (SEC Form 4) (tax withholding)

Chief People Officer Valente Manuela sold $21,430 worth of Ordinary Shares (4,241 units at $5.05) as part of a pre-agreed trading plan, decreasing direct ownership by 2% to 210,450 units (SEC Form 4) (tax liability)

Chief Technology Officer Verma Abhimanyu sold $26,957 worth of Ordinary Shares (5,285 units at $5.10) as part of a pre-agreed trading plan, decreasing direct ownership by 3% to 192,171 units (SEC Form 4) (tax liability)

Chief Scientific Officer Xu Zhenyu sold $38,242 worth of Ordinary Shares (7,393 units at $5.17) as part of a pre-agreed trading plan, decreasing direct ownership by 1% to 614,887 units (SEC Form 4) (for withholding tax)

Chief Sales Officer Puylaert Kevin sold $1,087 worth of Ordinary Shares (216 units at $5.03), decreasing direct ownership by 0.15% to 147,948 units (SEC Form 4) to satisfy withholding tax

Chief Executive Officer Muken Ross sold $51,354 worth of Ordinary Shares (9,838 units at $5.22) as part of a pre-agreed trading plan, decreasing direct ownership by 1% to 670,651 units (SEC Form 4) (tax withholding)

Chief Medical Officer Menu Philippe sold $38,156 worth of Ordinary Shares (7,393 units at $5.16) as part of a pre-agreed trading plan, decreasing direct ownership by 3% to 233,387 units (SEC Form 4) (withholding tax)

Executive Chairman Camblong Jurgi sold $118,164 worth of Ordinary Shares (22,486 units at $5.25) as part of a pre-agreed trading plan, decreasing direct ownership by 0.63% to 3,558,807 units (SEC Form 4) to satisfy tax liability

Executive Chairman Camblong Jurgi exercised 63,479 units of Ordinary Shares at a strike of $3.16 and sold $506,690 worth of Ordinary Shares (83,679 units at $6.06) as part of a pre-agreed trading plan, decreasing direct ownership by 0.56% to 3,581,293 units (SEC Form 4)

Chief Executive Officer Camblong Jurgi sold $298,155 worth of Ordinary Shares (51,442 units at $5.80) as part of a pre-agreed trading plan and exercised 31,940 units of Ordinary Shares at a strike of $3.16, decreasing direct ownership by 0.54% to 3,601,493 units (SEC Form 4)

Chief Technology Officer Verma Abhimanyu sold $38,229 worth of Ordinary Shares (6,944 units at $5.51) as part of a pre-agreed trading plan, decreasing direct ownership by 3% to 197,456 units (SEC Form 4) (withholding obligation)

Chief Medical Officer Menu Philippe sold $27,524 worth of Ordinary Shares (5,000 units at $5.50) as part of a pre-agreed trading plan, decreasing direct ownership by 2% to 240,780 units (SEC Form 4)

Chief Financial Officer Cardoza George sold $4,164 worth of Ordinary Shares (774 units at $5.38) as part of a pre-agreed trading plan, decreasing direct ownership by 0.25% to 310,684 units (SEC Form 4) to satisfy withholding obligation

President Muken Ross sold $2,270 worth of Ordinary Shares (422 units at $5.38) as part of a pre-agreed trading plan, decreasing direct ownership by 0.06% to 680,489 units (SEC Form 4) (for withholding tax)

Director Cox Troy was granted 19,724 units of Ordinary Shares, increasing direct ownership by 6% to 328,743 units (SEC Form 4)

Director Ossipow Vincent was granted 19,724 units of Ordinary Shares, increasing direct ownership by 4% to 522,860 units (SEC Form 4)

Director Hibbs Kathy L was granted 19,724 units of Ordinary Shares, increasing direct ownership by 22% to 109,492 units (SEC Form 4)

Director Hirsch Didier was granted 19,724 units of Ordinary Shares, increasing direct ownership by 9% to 240,220 units (SEC Form 4)

Director Cossery Jean-Michel was granted 19,724 units of Ordinary Shares, increasing direct ownership by 11% to 206,212 units (SEC Form 4)

Chief Scientific Officer Xu Zhenyu sold $20,056 worth of Ordinary Shares (4,000 units at $5.01) as part of a pre-agreed trading plan, decreasing direct ownership by 0.64% to 622,280 units (SEC Form 4)

Chief Medical Officer Menu Philippe sold $24,752 worth of Ordinary Shares (5,000 units at $4.95) as part of a pre-agreed trading plan, decreasing direct ownership by 2% to 245,780 units (SEC Form 4)

Chief Medical Officer Menu Philippe sold $24,774 worth of Ordinary Shares (5,000 units at $4.95) as part of a pre-agreed trading plan, decreasing direct ownership by 2% to 250,780 units (SEC Form 4)

President Muken Ross sold $3,501 worth of Ordinary Shares (761 units at $4.60) as part of a pre-agreed trading plan, decreasing direct ownership by 0.11% to 680,911 units (SEC Form 4) (tax liability)

Chief Scientific Officer Xu Zhenyu sold $2,798 worth of Ordinary Shares (608 units at $4.60) as part of a pre-agreed trading plan, decreasing direct ownership by 0.10% to 626,280 units (SEC Form 4) to satisfy tax liability

Chief Executive Officer Camblong Jurgi sold $20,658 worth of Ordinary Shares (4,486 units at $4.60) as part of a pre-agreed trading plan, decreasing direct ownership by 0.12% to 3,629,495 units (SEC Form 4) (withholding tax)

Chief Medical Officer Menu Philippe sold $2,800 worth of Ordinary Shares (608 units at $4.61) as part of a pre-agreed trading plan, decreasing direct ownership by 0.24% to 255,780 units (SEC Form 4) (tax withholding)

Chief Legal Officer Van Well Daan sold $3,149 worth of Ordinary Shares (684 units at $4.60) as part of a pre-agreed trading plan, decreasing direct ownership by 0.20% to 345,052 units (SEC Form 4) to satisfy tax liability

Chief People Officer Valente Manuela sold $1,747 worth of Ordinary Shares (380 units at $4.60) as part of a pre-agreed trading plan, decreasing direct ownership by 0.18% to 214,691 units (SEC Form 4) (tax withholding)

Chief Sales Officer Puylaert Kevin sold $150 worth of Ordinary Shares (33 units at $4.54), decreasing direct ownership by 0.02% to 148,164 units (SEC Form 4) to satisfy withholding tax

Chief Scientific Officer Xu Zhenyu sold $18,168 worth of Ordinary Shares (4,000 units at $4.54) as part of a pre-agreed trading plan, decreasing direct ownership by 0.63% to 626,888 units (SEC Form 4)

Chief Medical Officer Menu Philippe sold $23,344 worth of Ordinary Shares (5,000 units at $4.67) as part of a pre-agreed trading plan, decreasing direct ownership by 2% to 256,388 units (SEC Form 4)

Director Hibbs Kathy L sold $35,037 worth of Ordinary Shares (7,508 units at $4.67) as part of a pre-agreed trading plan, decreasing direct ownership by 8% to 89,768 units (SEC Form 4)

Chief Executive Officer Camblong Jurgi sold $43,241 worth of Ordinary Shares (8,500 units at $5.09) as part of a pre-agreed trading plan, decreasing direct ownership by 0.23% to 3,633,981 units (SEC Form 4)

Chief Medical Officer Menu Philippe sold $24,089 worth of Ordinary Shares (5,000 units at $4.82) as part of a pre-agreed trading plan, decreasing direct ownership by 2% to 261,388 units (SEC Form 4)

SEC Form 4 filed by Van Well Daan

SEC Form 4 filed by Xu Zhenyu

SEC Form 4 filed by Valente Manuela

SEC Form 4 filed by Menu Philippe

SEC Form 4 filed by Camblong Jurgi

SEC Form 4 filed by Muken Ross

SEC Form 4 filed by Puylaert Kevin

SEC Form 4 filed by Camblong Jurgi

SEC Form 4 filed by Xu Zhenyu

SEC Form 4 filed by Menu Philippe

SEC Form 4 filed by Muken Ross

SEC Form 4 filed by Xu Zhenyu

SEC Form 4 filed by Van Well Daan

SEC Form 4 filed by Camblong Jurgi

SEC Form 4 filed by Muken Ross

SEC Form 4 filed by Menu Philippe

SEC Form 4 filed by Van Well Daan