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Compare · AMGN vs PRME

AMGN vs PRME

Side-by-side comparison of Amgen Inc. (AMGN) and Prime Medicine Inc. (PRME): market cap, price performance, sector, and recent activity on the wire.

Summary

  • Both AMGN and PRME operate in Biotechnology: Biological Products (No Diagnostic Substances) (Health Care), so they compete in similar markets.
  • AMGN is the larger of the two at $202.95B, about 380.9x PRME ($532.8M).
  • Over the past year, AMGN is up 25.4% and PRME is down 26.7% - AMGN leads by 52.1 points.
  • PRME has been more active in the news (3 items in the past 4 weeks vs 1 for AMGN).
  • AMGN has more recent analyst coverage (25 ratings vs 16 for PRME).
PerformanceAMGN+25.39%PRME-26.72%
2025-07-28+0.00%2026-07-27
MetricAMGNPRME
Company
Amgen Inc.
Prime Medicine Inc.
Price
$377.78+0.47%
$2.98+1.36%
Market cap
$202.95B
$532.8M
1M return
+7.07%
-5.83%
1Y return
+25.39%
-26.72%
Industry
Biotechnology: Biological Products (No Diagnostic Substances)
Biotechnology: Biological Products (No Diagnostic Substances)
Exchange
NASDAQ
NASDAQ
IPO
1983
2022
News (4w)
1
3
Recent ratings
25
16
AMGN

Amgen Inc.

Amgen Inc. discovers, develops, manufactures, and delivers human therapeutics worldwide. It focuses on inflammation, oncology/hematology, bone health, cardiovascular disease, nephrology, and neuroscience areas. The company's products include Enbrel to treat plaque psoriasis, rheumatoid arthritis, and psoriatic arthritis; Neulasta that reduces the chance of infection due a low white blood cell count in patients cancer; Prolia to treat postmenopausal women with osteoporosis; Xgeva for skeletal-related events prevention; Otezla for the treatment of adult patients with plaque psoriasis, psoriatic arthritis, and oral ulcers associated with Behçet's disease; Aranesp to treat a lower-than-normal number of red blood cells and anemia; KYPROLIS to treat patients with relapsed or refractory multiple myeloma; and Repatha, which reduces the risks of myocardial infarction, stroke, and coronary revascularization. It also markets Nplate, Vectibix, MVASI, Parsabiv, EPOGEN, KANJINTI, BLINCYTO, Aimovig, EVENITY, AMGEVITATM, Sensipar/Mimpara, NEUPOGEN, IMLYGIC, Corlanor, and AVSOLA. Amgen Inc. serves healthcare providers, including physicians or their clinics, dialysis centers, hospitals, and pharmacies. It distributes its products through pharmaceutical wholesale distributors, as well as direct-to-consumer channels. The company has collaboration agreements with Novartis Pharma AG; UCB; Bayer HealthCare LLC; BeiGene, Ltd.; Eli Lilly and Company; Datos Health; and Verastem, Inc. to evaluate VS-6766 in combination with lumakrastm (Sotorasib) in patients with KRAS G12C-mutant non-small cell lung cancer. It has an agreement with Kyowa Kirin Co., Ltd. to jointly develop and commercialize KHK4083, a Phase 3-ready anti-OX40 fully human monoclonal antibody for the treatment of atopic dermatitis and other autoimmune diseases; and a strategic research and development collaboration with Neumora Therapeutics, Inc. Amgen Inc. was founded in 1980 and is headquartered in Thousand Oaks, California.

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