CALC insider transactions

SEC Form 4 filed by Bardin Stephen

SEC Form 4 filed by Leheny A. Rachel

SEC Form 4 filed by Hebbar Sudarshan

SEC Form 4 filed by Stauderman Kenneth A.

SEC Form 4 filed by Dunn Michael J.

SEC Form 4 filed by Roberts Eric W

SEC Form 4 filed by Director Glicklich Alan

CHIEF BUSINESS OFFICER Roberts Eric W bought $7,675 worth of shares (2,500 units at $3.07) (SEC Form 4)

CHIEF BUSINESS OFFICER Roberts Eric W bought $9,105 worth of shares (3,400 units at $2.68) (SEC Form 4)

CHIEF BUSINESS OFFICER Roberts Eric W bought $15,600 worth of shares (5,000 units at $3.12) (SEC Form 4)

CHIEF BUSINESS OFFICER Roberts Eric W bought $7,378 worth of shares (2,343 units at $3.15) (SEC Form 4)

CHIEF BUSINESS OFFICER Roberts Eric W bought $28,532 worth of shares (10,000 units at $2.85) (SEC Form 4)

CHIEF BUSINESS OFFICER Roberts Eric W bought $9,797 worth of shares (3,508 units at $2.79) (SEC Form 4)

CHIEF BUSINESS OFFICER Roberts Eric W bought $8,230 worth of shares (3,000 units at $2.74) and exercised 15,000 shares at a strike of $1.53, increasing direct ownership by 9% to 179,706 units (SEC Form 4)

Chief Medical Officer Hebbar Sudarshan bought $26,962 worth of shares (9,563 units at $2.82), increasing direct ownership by 18% to 61,539 units (SEC Form 4)

CHIEF BUSINESS OFFICER Roberts Eric W bought $14,709 worth of shares (5,076 units at $2.90) (SEC Form 4)

Chief Medical Officer Hebbar Sudarshan bought $16,361 worth of shares (5,976 units at $2.74), increasing direct ownership by 13% to 51,976 units (SEC Form 4)

Chief Scientific Officer Stauderman Kenneth A. bought $3,960 worth of shares (1,000 units at $3.96) and sold $3,650 worth of shares (1,000 units at $3.65), increasing direct ownership by 8% to 12,944 units (SEC Form 4)

CHIEF BUSINESS OFFICER Roberts Eric W bought $5,662 worth of shares (1,500 units at $3.77) (SEC Form 4)

CHIEF BUSINESS OFFICER Roberts Eric W bought $5,055 worth of shares (1,500 units at $3.37) (SEC Form 4)

CHIEF EXECUTIVE OFFICER Leheny A. Rachel bought $3,400 worth of shares (1,000 units at $3.40) (SEC Form 4)

Director Wilson Robert N bought $12,915 worth of shares (4,500 units at $2.87), increasing direct ownership by 1% to 422,029 units (SEC Form 4)

CHIEF BUSINESS OFFICER Roberts Eric W bought $5,760 worth of shares (2,000 units at $2.88) (SEC Form 4)

CHIEF BUSINESS OFFICER Roberts Eric W bought $15,810 worth of shares (6,500 units at $2.43) (SEC Form 4)

CHIEF EXECUTIVE OFFICER Leheny A. Rachel bought $6,175 worth of shares (2,500 units at $2.47) (SEC Form 4)

CHIEF BUSINESS OFFICER Roberts Eric W bought $8,024 worth of shares (5,000 units at $1.60) (SEC Form 4)

Chief Scientific Officer Stauderman Kenneth A. bought $1,850 worth of shares (1,000 units at $1.85) (SEC Form 4)

CHIEF BUSINESS OFFICER Roberts Eric W bought $6,483 worth of shares (4,500 units at $1.44) (SEC Form 4)

SEC Form 4 filed by Chief Medical Officer Hebbar Sudarshan

Chief Financial Officer Bardin Stephen bought $3,005 worth of shares (2,000 units at $1.50) (SEC Form 4)

SEC Form 4 filed by Chief Scientific Officer Stauderman Kenneth A.

SEC Form 4 filed by CHIEF BUSINESS OFFICER Roberts Eric W

SEC Form 4 filed by President and COO Dunn Michael J.

SEC Form 4 filed by CHIEF EXECUTIVE OFFICER Leheny A. Rachel

SEC Form 4 filed by Director Guerard Frederic

SEC Form 4 filed by Director Glicklich Alan

SEC Form 4 filed by Director Shaw Allan

SEC Form 4 filed by Director Wilson Robert N

SEC Form 4 filed by Director Middleton Fred A

CHIEF BUSINESS OFFICER Roberts Eric W bought $9,250 worth of shares (5,000 units at $1.85) (SEC Form 4)

CHIEF BUSINESS OFFICER Roberts Eric W bought $17,545 worth of shares (10,100 units at $1.74) (SEC Form 4)

Chief Financial Officer Bardin Stephen bought $1,690 worth of shares (1,000 units at $1.69), increasing direct ownership by 2% to 41,000 units (SEC Form 4)

SEC Form 4 filed by Chief Financial Officer Bardin Stephen

SEC Form 4 filed by Chief Scientific Officer Stauderman Kenneth A.

SEC Form 4 filed by President and COO Dunn Michael J.

SEC Form 4 filed by CHIEF BUSINESS OFFICER Roberts Eric W

SEC Form 4 filed by Chief Medical Officer Hebbar Sudarshan

SEC Form 4 filed by CHIEF EXECUTIVE OFFICER Leheny A. Rachel

SEC Form 4 filed by Director Glicklich Alan

SEC Form 3 filed by new insider Glicklich Alan

Director Middleton Fred A bought $12,720 worth of shares (4,800 units at $2.65), increasing direct ownership by 15% to 36,514 units (SEC Form 4)

New insider Bardin Stephen claimed ownership of 40,000 shares (SEC Form 3)

Amendment: CHIEF BUSINESS OFFICER Roberts Eric W bought $8,040 worth of shares (3,000 units at $2.68) (SEC Form 4)

Large owner Sanderling Venture Partners Vi Co Investment Fund Lp bought $329,040 worth of shares (87,744 units at $3.75), increasing direct ownership by 12% to 814,300 units (SEC Form 4)

Director Middleton Fred A bought $404,040 worth of shares (107,744 units at $3.75), increasing direct ownership by 171% to 31,714 units (SEC Form 4)

CHIEF EXECUTIVE OFFICER Leheny A. Rachel bought $75,000 worth of shares (20,000 units at $3.75), increasing direct ownership by 18% to 130,926 units (SEC Form 4)

CHIEF BUSINESS OFFICER Roberts Eric W bought $199,999 worth of shares (53,333 units at $3.75), increasing direct ownership by 48% to 164,706 units (SEC Form 4)

Director Wilson Robert N bought $199,999 worth of shares (53,333 units at $3.75), increasing direct ownership by 15% to 417,529 units (SEC Form 4)

President and COO Dunn Michael J. exercised 11,761 shares at a strike of $1.39 (SEC Form 4)

SEC Form 4 filed by Director Guerard Frederic