CPRX insider transactions

Chief HR Officer Russo Gregg returned $14,994 worth of shares to the company (476 units at $31.50), closing all direct ownership in the company (SEC Form 4) (withholding tax)

Chief Legal Officer Elsbernd Brian returned $7,638,782 worth of shares to the company (242,501 units at $31.50), closing all direct ownership in the company (SEC Form 4) (for tax liability)

SEC Form 4 filed by Director Curran Daniel J. to cover taxes

Director Thompson Tamar returned $118,850 worth of shares to the company (3,773 units at $31.50), closing all direct ownership in the company (SEC Form 4) to satisfy withholding tax

Chief Op. & Scientific Officer Miller Steve returned $34,454,794 worth of shares to the company (1,093,803 units at $31.50), closing all direct ownership in the company (SEC Form 4) (tax withholding)

Director Tierney David S returned $12,074,391 worth of shares to the company (383,314 units at $31.50), closing all direct ownership in the company (SEC Form 4) (tax liability)

Chief Strategy Officer Sundaram Preethi returned $1,726,326 worth of shares to the company (54,804 units at $31.50), closing all direct ownership in the company (SEC Form 4) to cover withholding tax

Chairman of Board of Directors Mcenany Patrick J returned $131,404,108 worth of shares to the company (4,171,559 units at $31.50), closing all direct ownership in the company (SEC Form 4) (for tax liability)

President and CEO Daly Richard J returned $8,544,879 worth of shares to the company (271,266 units at $31.50), closing all direct ownership in the company (SEC Form 4) (for withholding tax)

Chief Commercial Officer Del Carmen Jeffrey returned $451,616 worth of shares to the company (14,337 units at $31.50), closing all direct ownership in the company (SEC Form 4) (for tax liability)

Chief Medical Officer Andrews William T. returned $72,734 worth of shares to the company (2,309 units at $31.50), closing all direct ownership in the company (SEC Form 4) (tax withholding)

Director Denkhaus Donald A returned $15,711,350 worth of shares to the company (498,773 units at $31.50), closing all direct ownership in the company (SEC Form 4) (withholding tax)

Chief Financial Officer Kalb Michael Wayne returned $430,448 worth of shares to the company (13,665 units at $31.50), closing all direct ownership in the company (SEC Form 4) to satisfy withholding obligation

Director Harper Molly returned $116,361 worth of shares to the company (3,694 units at $31.50), closing all direct ownership in the company (SEC Form 4) to cover withholding tax

Chief Medical Officer Andrews William T. converted options into 3,052 shares and covered exercise/tax liability with 743 shares (SEC Form 4) (withholding tax)

Chief HR Officer Russo Gregg covered exercise/tax liability with 211 shares and converted options into 687 shares (SEC Form 4)

Executive Vice President & CFO Kalb Michael Wayne converted options into 7,139 shares and covered exercise/tax liability with 2,080 shares, increasing direct ownership by 59% to 13,665 units (SEC Form 4)

President and CEO Daly Richard J covered exercise/tax liability with 10,577 shares and converted options into 42,105 shares, increasing direct ownership by 13% to 271,266 units (SEC Form 4)

Director Tierney David S converted options into 1,334 shares, increasing direct ownership by 0.35% to 383,314 units (SEC Form 4)

Chairman of Board of Directors Mcenany Patrick J converted options into 26,334 shares and covered exercise/tax liability with 6,786 shares, increasing direct ownership by 0.47% to 4,171,559 units (SEC Form 4)

Director Denkhaus Donald A converted options into 1,334 shares, increasing direct ownership by 0.27% to 498,773 units (SEC Form 4)

Chief Compliance/Legal Officer Elsbernd Brian converted options into 6,667 shares and covered exercise/tax liability with 2,623 shares, increasing direct ownership by 2% to 242,501 units (SEC Form 4)

Chief Op. & Scientific Officer Miller Steve converted options into 14,000 shares, increasing direct ownership by 1% to 1,093,803 units (SEC Form 4)

Director Harper Molly converted options into 1,334 shares, increasing direct ownership by 57% to 3,694 units (SEC Form 4)

President and CEO Daly Richard J converted options into 1,334 shares and covered exercise/tax liability with 524 shares, increasing direct ownership by 0.34% to 239,738 units (SEC Form 4)

Chief Strategy Officer Sundaram Preethi converted options into 6,667 shares and covered exercise/tax liability with 2,369 shares, increasing direct ownership by 9% to 54,804 units (SEC Form 4)

Chief Commercial Officer Del Carmen Jeffrey converted options into 8,667 shares and covered exercise/tax liability with 3,839 shares, increasing direct ownership by 51% to 14,337 units (SEC Form 4)

Director Harper Molly exercised 20,000 shares at a strike of $5.78 and sold $621,920 worth of shares (26,746 units at $23.25), decreasing direct ownership by 74% to 2,360 units (SEC Form 4)

Chairman of Board of Directors Mcenany Patrick J converted options into 3,534 shares, increasing direct ownership by 0.09% to 4,152,011 units (SEC Form 4)

Director Harper Molly converted options into 1,413 shares, increasing direct ownership by 18% to 9,106 units (SEC Form 4)

Chief Compliance/Legal Officer Elsbernd Brian converted options into 7,067 shares and covered exercise/tax liability with 2,780 shares, increasing direct ownership by 2% to 238,457 units (SEC Form 4)

Chief Op. & Scientific Officer Miller Steve converted options into 11,873 shares, increasing direct ownership by 1% to 1,079,803 units (SEC Form 4)

Director Denkhaus Donald A converted options into 1,413 shares, increasing direct ownership by 0.28% to 497,439 units (SEC Form 4)

Director Thompson Tamar converted options into 1,413 shares, increasing direct ownership by 60% to 3,773 units (SEC Form 4)

Director Tierney David S converted options into 1,413 shares, increasing direct ownership by 0.37% to 381,980 units (SEC Form 4)

Chief Strategy Officer Sundaram Preethi converted options into 6,855 shares and covered exercise/tax liability with 1,669 shares, increasing direct ownership by 11% to 50,506 units (SEC Form 4)

Chief Commercial Officer Del Carmen Jeffrey converted options into 8,039 shares and covered exercise/tax liability with 2,492 shares, increasing direct ownership by 140% to 9,509 units (SEC Form 4)

Chairman of Board of Directors Mcenany Patrick J gifted 135,000 shares, decreasing direct ownership by 5% to 4,148,477 units (SEC Form 4)

Chief Commercial Officer Del Carmen Jeffrey exercised 10,983 shares at a strike of $4.21 and sold $256,244 worth of shares (10,983 units at $23.33) (SEC Form 4)

Executive Vice President & CFO Kalb Michael Wayne converted options into 6,894 shares and covered exercise/tax liability with 2,485 shares, increasing direct ownership by 105% to 8,606 units (SEC Form 4)

Director Thompson Tamar converted options into 947 shares, increasing direct ownership by 67% to 2,360 units (SEC Form 4)

SEC Form 4 filed by Chief HR Officer Russo Gregg

Chief Op. & Scientific Officer Miller Steve converted options into 8,267 shares, increasing direct ownership by 0.78% to 1,067,930 units (SEC Form 4)

Director Tierney David S converted options into 947 shares, increasing direct ownership by 0.25% to 380,567 units (SEC Form 4)

Chief Strategy Officer Sundaram Preethi converted options into 5,603 shares and covered exercise/tax liability with 1,364 shares, increasing direct ownership by 10% to 45,320 units (SEC Form 4)

SEC Form 4 filed by Director Curran Daniel J.

President and CEO Daly Richard J converted options into 20,006 shares and covered exercise/tax liability with 7,872 shares, increasing direct ownership by 5% to 238,928 units (SEC Form 4)

Chief Commercial Officer Del Carmen Jeffrey converted options into 5,603 shares and covered exercise/tax liability with 1,641 shares (SEC Form 4)

Chief Compliance/Legal Officer Elsbernd Brian covered exercise/tax liability with 2,030 shares and converted options into 5,161 shares, increasing direct ownership by 1% to 234,170 units (SEC Form 4)

Director Denkhaus Donald A converted options into 947 shares, increasing direct ownership by 0.19% to 496,026 units (SEC Form 4)

Chairman of Board of Directors Mcenany Patrick J converted options into 1,775 shares, increasing direct ownership by 0.04% to 4,283,477 units (SEC Form 4)

Director Harper Molly converted options into 947 shares, increasing direct ownership by 14% to 7,693 units (SEC Form 4)

SEC Form 4 filed by Chief Medical Officer Andrews William T.

Chief Compliance/Legal Officer Elsbernd Brian increased direct ownership by 21% to 231,039 units (SEC Form 4)

Chief Compliance/Legal Officer Elsbernd Brian sold $609,000 worth of shares (30,000 units at $20.30) and exercised 112,475 shares at a strike of $2.24, increasing direct ownership by 44% to 271,039 units (SEC Form 4)

Chief Compliance/Legal Officer Elsbernd Brian exercised 50,000 shares at a strike of $2.24 and sold $987,200 worth of shares (50,000 units at $19.74) (SEC Form 4)

Director Tierney David S exercised 50,000 shares at a strike of $2.24 and sold $525,200 worth of shares (26,000 units at $20.20), increasing direct ownership by 7% to 379,620 units (SEC Form 4)

Chief Op. & Scientific Officer Miller Steve exercised 225,000 shares at a strike of $2.24 and sold $2,332,200 worth of shares (115,000 units at $20.28), increasing direct ownership by 12% to 1,059,663 units (SEC Form 4)

President and CEO Daly Richard J exercised 50,000 shares at a strike of $2.24 and sold $473,641 worth of shares (22,970 units at $20.62), increasing direct ownership by 14% to 226,794 units (SEC Form 4)

New insider Curran Daniel J. claimed no ownership of stock in the company (SEC Form 3)