DFTX insider transactions

Chief Legal Officer Sullivan Mark sold $585,750 worth of shares (13,008 units at $45.03) as part of a pre-agreed trading plan, decreasing direct ownership by 4% to 320,571 units (SEC Form 4) (withholding tax)

Chief Medical Officer Karlin Daniel sold $451,876 worth of shares (10,035 units at $45.03) as part of a pre-agreed trading plan, decreasing direct ownership by 2% to 503,282 units (SEC Form 4) (withholding obligation)

Chief Financial Officer Roberts Brandi sold $135,675 worth of shares (3,013 units at $45.03) as part of a pre-agreed trading plan, decreasing direct ownership by 1% to 209,487 units (SEC Form 4) (withholding obligation)

Chief Executive Officer Barrow Robert sold $1,315,236 worth of shares (29,208 units at $45.03) as part of a pre-agreed trading plan, decreasing direct ownership by 3% to 1,098,246 units (SEC Form 4) to satisfy withholding obligation

Chief Commercial Officer Wiley Matthew T. sold $129,101 worth of shares (2,867 units at $45.03) as part of a pre-agreed trading plan, decreasing direct ownership by 2% to 174,633 units (SEC Form 4) (withholding obligation)

Chief Medical Officer Karlin Daniel was granted 100,000 shares, increasing direct ownership by 24% to 513,317 units (SEC Form 4)

Chief Executive Officer Barrow Robert was granted 375,000 shares, increasing direct ownership by 50% to 1,127,454 units (SEC Form 4)

Chief Legal Officer Sullivan Mark was granted 62,500 shares, increasing direct ownership by 23% to 333,579 units (SEC Form 4)

Chief Financial Officer Roberts Brandi was granted 62,500 shares, increasing direct ownership by 42% to 212,500 units (SEC Form 4)

Chief Commercial Officer Wiley Matthew T. was granted 62,500 shares, increasing direct ownership by 54% to 177,500 units (SEC Form 4)

Director Vallone Carol A was granted 4,666 shares, increasing direct ownership by 28% to 21,210 units (SEC Form 4)

Director Crystal Roger was granted 4,666 shares, increasing direct ownership by 24% to 24,289 units (SEC Form 4)

Director Gryska David W was granted 4,666 shares, increasing direct ownership by 31% to 19,900 units (SEC Form 4)

Director Adsett Roger was granted 3,555 shares (SEC Form 4)

Director Krebs Andreas was granted 4,666 shares, increasing direct ownership by 31% to 19,773 units (SEC Form 4)

Director Bruhn Suzanne Louise was granted 4,666 shares, increasing direct ownership by 24% to 24,289 units (SEC Form 4)

SEC Form 4 filed by Karlin Daniel

SEC Form 4 filed by Sullivan Mark

SEC Form 4 filed by Barrow Robert

Chief Commercial Officer Wiley Matthew T. was granted 115,000 shares (SEC Form 4)

Chief Financial Officer Roberts Brandi was granted 150,000 shares (SEC Form 4)

Chief Legal Officer Sullivan Mark was granted 125,000 shares, increasing direct ownership by 44% to 407,576 units (SEC Form 4)

Chief Medical Officer Karlin Daniel was granted 150,000 shares, increasing direct ownership by 35% to 575,025 units (SEC Form 4)

Chief Executive Officer Barrow Robert was granted 320,000 shares, increasing direct ownership by 41% to 1,098,477 units (SEC Form 4)

SEC Form 4 filed by Director Adsett Roger

SEC Form 3 filed by new insider Adsett Roger