Sionna Therapeutics (SION) director Orbimed Advisors sold 510,583 shares for $22.9M at an average $44.94 under a 10b5-1 plan

Insider transactions reported

Orbimed Advisors Llc (director at Sionna Therapeutics Inc., SION) reported that they sold 510,583 shares for $22.9M at an average $44.94 between Apr 14, 2026 and Apr 16, 2026. After these transactions the filing shows 3,020,119 shares held indirectly (See footnotes).

Reporting person

Orbimed Advisors Llc

Holdings before and after

• Common Stock: 3,530,702 to 3,020,119 indirect, See footnotes

Footnotes from the filing

1. 1. These securities were sold pursuant to a 10b5-1 plan.
2. 2. These securities are held of record by OrbiMed Private Investments VIII, LP ( OPI VIII ). OrbiMed Capital GP VIII LLC ( GP VIII ) is the general partner of OPI VIII and OrbiMed Advisors LLC ( OrbiMed Advisors ) is the managing member of GP VIII. By virtue of such relationships, GP VIII and OrbiMed Advisors may be deemed to have voting and investment power with respect to the shares held by OPI VIII and as a result may be deemed to have beneficial ownership of such shares. OrbiMed Advisors exercises investment and voting power through a management committee comprised of Carl L. Gordon, Sven H. Borho, and W. Carter Neild, each of whom disclaims beneficial ownership of the shares held by OPI VIII.
3. 3. This report on Form 4 is jointly filed by OrbiMed Advisors and GP VIII. Each of the Reporting Persons disclaims beneficial ownership of the securities reported herein for purposes of Rule 16a-1(a) under the Securities Exchange Act of 1934, as amended (the Exchange Act ), except to the extent of its pecuniary interest therein, if any. The Reporting Persons have designated a representative, Peter A. Thompson, a member of OrbiMed Advisors, to serve on the Issuer's board of directors. This report shall not be deemed an admission that any such entity or person is a beneficial owner of such securities for purposes of Section 16 of the Exchange Act, or for any other purpose.

Transaction codes in this filing

Open-market sale:

Code S marks a sale in the open market or a private deal. The insider received cash for these securities.

FAQ