Compare · PYPD vs SYK

PYPD vs SYK

Side-by-side comparison of PolyPid Ltd. (PYPD) and Stryker Corporation (SYK): market cap, price performance, sector, and recent activity on the wire.

Summary

  • Both PYPD and SYK operate in Medical/Dental Instruments (Health Care), so they compete in similar markets.
  • SYK is the larger of the two at $117.88B, about 927.1x PYPD ($127.2M).
  • Over the past year, PYPD is up 73.8% and SYK is down 14.5% - PYPD leads by 88.3 points.
  • SYK has been more active in the news (12 items in the past 4 weeks vs 8 for PYPD).
  • SYK has more recent analyst coverage (25 ratings vs 7 for PYPD).
PerformancePYPD+73.76%SYK-14.51%
2025-11-14+0.00%2026-11-13
MetricPYPDSYK
Company
PolyPid Ltd.
Stryker Corporation
Price
-
-
Market cap
$127.2M
$117.88B
1M return
+28.89%
+5.56%
1Y return
+73.76%
-14.51%
Industry
Medical/Dental Instruments
Medical/Dental Instruments
Exchange
NASDAQ
NYSE
IPO
2020
News (4w)
8
12
Recent ratings
7
25
PYPD

PolyPid Ltd.

PolyPid Ltd., a late-stage biopharma company, develops, manufactures, and commercializes products based on polymer-lipid encapsulation matrix (PLEX) platform to address unmet medical needs. Its lead product includes D-PLEX100, which is in Phase 3 clinical trial for the prevention of sternal (bone) surgical site infections (SSIs), as well as for the prevention of abdominal (soft tissue) SSIs. PolyPid Ltd. was incorporated in 2008 and is headquartered in Petah Tikva, Israel.

SYK

Stryker Corporation

Stryker Corporation operates as a medical technology company. The company operates through three segments: Orthopaedics, MedSurg, and Neurotechnology and Spine. The Orthopaedics segment provides implants for use in hip and knee joint replacements, and trauma and extremities surgeries. The MedSurg segment offers surgical equipment and surgical navigation systems, endoscopic and communications systems, patient handling, emergency medical equipment and intensive care disposable products, reprocessed and remanufactured medical devices, and other medical device products that are used in various medical specialties. The Neurotechnology and Spine segment provides neurotechnology products, which include products used for minimally invasive endovascular techniques; products for brain and open skull based surgical procedures; orthobiologic and biosurgery products, such as synthetic bone grafts and vertebral augmentation products; and minimally invasive products for the treatment of acute ischemic and hemorrhagic stroke. This segment also offers spinal implant products comprising cervical, thoracolumbar, and interbody systems that are used in spinal injury, deformity, and degenerative therapies. The company sells its products to doctors, hospitals, and other healthcare facilities through company-owned subsidiaries and branches, as well as third-party dealers and distributors in approximately 75 countries. Stryker Corporation was founded in 1941 and is headquartered in Kalamazoo, Michigan.