For the twelve months ended Sep 30, 2026, Syndax Pharmaceuticals Inc. reported $289.68M of revenue and -$209.48M of net income.
SNDX revenue was $83.30M in fiscal Q3 2026 (ended Sep 30, 2026), up 81.6% from a year earlier and up 14.4% from the prior quarter. For the full fiscal 2025 it was $172.35M, up 627.8% from fiscal 2024. Compound annual growth was +157.7% over 5 years and +75.4% over 10 years. Fiscal 2025 is the highest of the 11 fiscal years on file.
SNDX net income was -$49.43M in fiscal Q3 2026 (ended Sep 30, 2026), compared with -$60.72M a year earlier. For the full fiscal 2025 it was -$285.42M, compared with -$318.76M in fiscal 2024.
SNDX diluted EPS was -$0.55 in fiscal Q3 2026 (ended Sep 30, 2026), compared with -$0.70 a year earlier. For the full fiscal 2025 it was -$3.29, compared with -$3.72 in fiscal 2024.
SNDX free cash flow was -$323.17M for fiscal 2025 (ended Dec 31, 2025), compared with -$274.90M in fiscal 2024.
| Line item | Dec 31, 2025 | Dec 31, 2024 | Dec 31, 2023 | Dec 31, 2022 | Dec 31, 2021 | Dec 31, 2020 | Dec 31, 2019 | Dec 31, 2018 | Dec 31, 2017 | Dec 31, 2016 |
|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $172.35M | $23.68M | $0 | $0 | $139.71M | $1.52M | $1.52M | $1.52M | $2.11M | $1.22M |
| Research and development | $258.78M | $241.65M | $163.03M | $118.50M | $88.25M | $50.44M | $42.99M | $60.11M | $48.20M | $31.66M |
| Selling, general and admin | $179.68M | $120.88M | $66.92M | $33.26M | $25.24M | $22.50M | $16.06M | $17.29M | $15.86M | $13.32M |
| Operating income | -$273.08M | -$339.67M | -$229.95M | -$151.76M | $26.22M | -$71.42M | -$57.54M | -$75.88M | -$61.95M | -$43.77M |
| Interest expense | $6.0K | -$1.0K | $208.0K | $3.14M | $1.90M | $2.36M | - | - | - | - |
| Income tax | $433.0K | - | - | - | $0 | $0 | $0 | $0 | $0 | $0 |
| Net income | -$285.42M | -$318.76M | -$209.36M | -$149.34M | $24.93M | -$73.16M | -$56.05M | -$73.96M | -$60.80M | -$44.47M |
| EPS, basic | -$3.29 | -$3.72 | -$2.98 | -$2.46 | $0.48 | -$1.87 | -$1.84 | -$2.92 | -$2.90 | -$3.22 |
| EPS, diluted | -$3.29 | -$3.72 | -$2.98 | -$2.46 | $0.46 | -$1.87 | -$1.84 | -$2.92 | -$2.90 | -$3.22 |
| Diluted shares | 86.6M | 85.6M | 70.4M | 60.8M | 53.6M | 41.3M | 30.5M | 25.4M | 21.0M | 14.6M |
| Line item | Dec 31, 2025 | Dec 31, 2024 | Dec 31, 2023 | Dec 31, 2022 | Dec 31, 2021 | Dec 31, 2020 | Dec 31, 2019 | Dec 31, 2018 | Dec 31, 2017 | Dec 31, 2016 |
|---|---|---|---|---|---|---|---|---|---|---|
| Cash and equivalents | $134.93M | $154.08M | $295.39M | $74.36M | $221.97M | $115.24M | $24.61M | $33.77M | $35.17M | $23.84M |
| Short-term investments | $259.14M | $418.80M | $275.30M | $401.45M | $217.97M | $177.82M | $35.17M | $47.14M | $94.81M | $81.49M |
| Receivables | $38.00M | $7.60M | $0 | - | - | - | - | - | - | - |
| Inventory | $32.75M | $366.0K | $0 | - | - | - | - | - | - | - |
| Current assets | $528.08M | $603.06M | $580.88M | $489.79M | $448.40M | $298.86M | $62.33M | $83.35M | $133.44M | $108.51M |
| Total assets | $529.71M | $724.82M | $612.88M | $497.24M | $449.66M | $300.61M | $63.52M | $83.94M | $137.19M | $109.01M |
| Current liabilities | $120.12M | $103.55M | $58.10M | $29.07M | $20.68M | $18.87M | $18.37M | $16.11M | $15.80M | $10.37M |
| Short-term debt | $343.91M | $343.68M | $0 | - | - | - | - | - | - | - |
| Long-term debt | $0 | - | - | - | - | - | - | - | - | - |
| Total debt | $343.91M | - | - | - | - | - | - | - | - | - |
| Total liabilities | $465.08M | $436.69M | $58.68M | $29.79M | $41.29M | $48.42M | $31.93M | $30.89M | $32.87M | $24.87M |
| Shareholders' equity | $64.63M | $288.12M | $554.20M | $467.45M | $408.37M | $252.19M | $31.60M | $53.05M | $104.32M | $84.14M |
| Line item | Dec 31, 2025 | Dec 31, 2024 | Dec 31, 2023 | Dec 31, 2022 | Dec 31, 2021 | Dec 31, 2020 | Dec 31, 2019 | Dec 31, 2018 | Dec 31, 2017 | Dec 31, 2016 |
|---|---|---|---|---|---|---|---|---|---|---|
| Operating cash flow | -$322.98M | -$274.90M | -$160.60M | -$133.68M | $29.13M | -$71.26M | -$50.61M | -$68.53M | -$47.37M | -$35.16M |
| Capital expenditures | $187.0K | $0 | $0 | $0 | $129.0K | $0 | - | $187.0K | $84.0K | $261.0K |
| Free cash flow | -$323.17M | -$274.90M | -$160.60M | -$133.68M | $29.00M | -$71.26M | - | -$68.72M | -$47.45M | -$35.42M |
| Investing cash flow | $290.04M | -$219.78M | $117.61M | -$186.19M | -$40.87M | -$142.53M | $12.78M | $51.40M | -$17.07M | -$18.28M |
| Financing cash flow | $13.68M | $353.37M | $264.13M | $172.25M | $118.46M | $304.42M | $28.57M | $15.73M | $75.72M | $54.20M |
| Stock-based compensation | $47.50M | $43.03M | $30.95M | $16.02M | $13.32M | $9.06M | $6.00M | $6.20M | $5.45M | $4.71M |
| Line item | Dec 31, 2025 | Dec 31, 2024 | Dec 31, 2023 | Dec 31, 2022 | Dec 31, 2021 | Dec 31, 2020 | Dec 31, 2019 | Dec 31, 2018 | Dec 31, 2017 | Dec 31, 2016 |
|---|---|---|---|---|---|---|---|---|---|---|
| Revenue growth, YoY | 627.8% | - | - | -100.0% | 9109.6% | 0.0% | 0.0% | -28.0% | 72.8% | 94.6% |
| Operating margin | -158.4% | -1434.4% | - | - | 18.8% | -4708.2% | -3792.9% | -5001.7% | -2939.0% | -3587.4% |
| Net margin | -165.6% | -1346.1% | - | - | 17.8% | -4822.5% | -3694.6% | -4875.5% | -2884.3% | -3645.2% |
| Free cash flow margin | -187.5% | -1160.9% | - | - | 20.8% | -4697.4% | - | -4529.9% | -2251.2% | -2903.1% |
| Return on equity | -441.6% | -110.6% | -37.8% | -31.9% | 6.1% | -29.0% | -177.4% | -139.4% | -58.3% | -52.9% |
| Return on assets | -53.9% | -44.0% | -34.2% | -30.0% | 5.5% | -24.3% | -88.2% | -88.1% | -44.3% | -40.8% |
| Current ratio | 4.40 | 5.82 | 10.00 | 16.85 | 21.68 | 15.84 | 3.39 | 5.18 | 8.45 | 10.47 |
| Debt to equity | 5.32 | - | - | - | - | - | - | - | - | - |
| Line item | Sep 30, 2026 | Jun 30, 2026 | Mar 31, 2026 | Dec 31, 2025 | Sep 30, 2025 | Jun 30, 2025 | Mar 31, 2025 | Dec 31, 2024 | Sep 30, 2024 | Jun 30, 2024 | Mar 31, 2024 | Dec 31, 2023 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $83.30M | $72.79M | $64.86M | $68.73M | $45.87M | $37.96M | $20.04M | $7.68M | $12.50M | $3.50M | $0 | $0 |
| Research and development | $67.48M | $68.04M | $58.84M | $78.64M | $56.28M | $62.23M | $61.64M | $65.53M | $70.97M | $48.66M | $56.49M | $55.13M |
| Selling, general and admin | $43.72M | $41.54M | $37.59M | $49.93M | $44.92M | $43.80M | $41.03M | $37.69M | $31.11M | $29.06M | $23.02M | $22.78M |
| Operating income | -$41.90M | -$39.99M | -$34.20M | -$62.55M | -$57.43M | -$69.35M | -$83.76M | -$96.36M | -$89.58M | -$74.22M | -$79.51M | -$77.91M |
| Interest expense | $2.0K | $2.0K | $0 | $0 | $0 | $4.0K | $2.0K | -$124.0K | $23.0K | $45.0K | $55.0K | $63.0K |
| Income tax | $0 | $0 | $0 | $433.0K | $0 | $0 | $0 | - | $0 | $0 | $0 | - |
| Net income | -$49.43M | -$49.36M | -$42.67M | -$68.01M | -$60.72M | -$71.85M | -$84.85M | -$94.17M | -$84.13M | -$68.06M | -$72.40M | -$72.47M |
| EPS, basic | -$0.55 | -$0.55 | -$0.48 | -$0.78 | -$0.70 | -$0.83 | -$0.98 | -$1.09 | -$0.98 | -$0.80 | -$0.85 | -$1.02 |
| EPS, diluted | -$0.55 | -$0.55 | -$0.48 | -$0.78 | -$0.70 | -$0.83 | -$0.98 | -$1.09 | -$0.98 | -$0.80 | -$0.85 | -$1.02 |
| Diluted shares | 89.8M | 89.0M | 88.3M | - | 86.6M | 86.3M | 86.2M | - | 85.4M | 85.3M | 85.2M | - |
| Line item | Sep 30, 2026 | Jun 30, 2026 | Mar 31, 2026 | Dec 31, 2025 | Sep 30, 2025 | Jun 30, 2025 | Mar 31, 2025 | Dec 31, 2024 | Sep 30, 2024 | Jun 30, 2024 | Mar 31, 2024 | Dec 31, 2023 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash and equivalents | $135.94M | $336.48M | $130.89M | $134.93M | $116.81M | $108.64M | $153.99M | $154.08M | $133.02M | $105.40M | $114.61M | $295.39M |
| Short-term investments | $291.16M | $211.38M | $221.17M | $259.14M | $319.17M | $346.60M | $358.20M | $418.80M | $256.59M | $319.70M | $319.96M | $275.30M |
| Receivables | - | - | - | $38.00M | - | - | - | $7.60M | - | - | - | $0 |
| Inventory | $39.38M | $33.16M | $34.95M | $32.75M | $25.00M | $17.70M | $4.66M | $366.0K | - | - | - | $0 |
| Current assets | $567.44M | $675.04M | $471.18M | $528.08M | $529.83M | $531.68M | $548.75M | $603.06M | $414.81M | $446.06M | $453.90M | $580.88M |
| Total assets | $692.67M | $703.65M | $472.67M | $529.71M | $551.79M | $596.15M | $640.71M | $724.82M | $425.81M | $476.95M | $543.03M | $612.88M |
| Current liabilities | $120.96M | $99.68M | $86.17M | $120.12M | $114.19M | $112.99M | $94.55M | $103.55M | $59.38M | $42.47M | $50.80M | $58.10M |
| Short-term debt | $344.10M | $344.03M | $343.96M | $343.91M | $343.91M | $343.85M | $343.79M | $343.68M | - | - | - | $0 |
| Long-term debt | $244.19M | $244.09M | - | $0 | - | - | - | - | - | - | - | - |
| Total debt | $588.28M | $588.12M | - | $343.91M | - | - | - | - | - | - | - | - |
| Total liabilities | $709.85M | $688.55M | $431.05M | $465.08M | $436.36M | $438.73M | $425.65M | $436.69M | $59.38M | $42.61M | $51.14M | $58.68M |
| Shareholders' equity | -$17.18M | $15.10M | $41.62M | $64.63M | $115.43M | $157.42M | $215.06M | $288.12M | $366.43M | $434.34M | $491.89M | $554.20M |
| Line item | Sep 30, 2026 | Jun 30, 2026 | Mar 31, 2026 | Dec 31, 2025 | Sep 30, 2025 | Jun 30, 2025 | Mar 31, 2025 | Dec 31, 2024 | Sep 30, 2024 | Jun 30, 2024 | Mar 31, 2024 | Dec 31, 2023 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating cash flow | -$27.25M | -$30.27M | -$50.34M | -$69.49M | -$70.53M | -$87.80M | -$95.16M | -$57.39M | -$62.32M | -$71.64M | -$83.55M | -$41.35M |
| Investing cash flow | -$176.47M | -$16.91M | $38.39M | $81.58M | $72.43M | $41.89M | $94.14M | -$268.97M | $86.85M | $61.75M | -$99.40M | -$16.29M |
| Financing cash flow | $3.19M | $252.77M | $7.92M | $5.92M | $6.28M | $551.0K | $930.0K | $347.43M | $3.10M | $676.0K | $2.17M | $258.48M |
| Stock-based compensation | $15.29M | $14.01M | $12.05M | $11.25M | $12.08M | $13.79M | $10.38M | $12.30M | $11.93M | $9.90M | $8.90M | $8.33M |
| Line item | Sep 30, 2026 | Jun 30, 2026 | Mar 31, 2026 | Dec 31, 2025 | Sep 30, 2025 | Jun 30, 2025 | Mar 31, 2025 | Dec 31, 2024 | Sep 30, 2024 | Jun 30, 2024 | Mar 31, 2024 | Dec 31, 2023 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue growth, YoY | 81.6% | 91.8% | 223.6% | 794.9% | 267.0% | 984.5% | - | - | - | - | - | - |
| Operating margin | -50.3% | -54.9% | -52.7% | -91.0% | -125.2% | -182.7% | -417.9% | -1254.8% | -716.6% | -2120.5% | - | - |
| Net margin | -59.3% | -67.8% | -65.8% | -99.0% | -132.4% | -189.3% | -423.3% | -1226.2% | -673.0% | -1944.7% | - | - |
| Current ratio | 4.69 | 6.77 | 5.47 | 4.40 | 4.64 | 4.71 | 5.80 | 5.82 | 6.99 | 10.50 | 8.93 | 10.00 |
| Debt to equity | - | 38.95 | - | 5.32 | - | - | - | - | - | - | - | - |
Source: XBRL data Syndax Pharmaceuticals Inc. files with the SEC, latest filing dated Nov 2, 2026 (see filings on SEC EDGAR). Provided for information only, not investment advice. Check the filing before relying on a number.
* Worked out from the filings rather than stated in them: Q4 is the full year less the first nine months.
Per-share figures are as filed. The filings show no stock split in these periods.
EPS growth is left out where the share count moved enough to suggest a split the filings do not show. Growth rates need a positive starting figure. CAGR is compound annual growth between fiscal years. The CSV holds every period on file, in full figures, from the same SEC filings.
| Company | Revenue | Growth | Net income | Net margin | Market cap |
|---|---|---|---|---|---|
| SNDX | $289.68M | +159.7% | -$209.48M | -72.3% | $854.0M |
| LLY | $86.46B | +45.5% | $27.58B | 31.9% | $1.35T |
| JNJ | $99.33B | +7.8% | $16.09B | 16.2% | $675.92B |
| ABBV | $66.01B | +10.7% | $10.34B | 15.7% | $519.48B |
| MRK | $67.38B | +4.9% | $2.45B | 3.6% | $364.98B |
| NVS | $54.53B | +8.4% | $13.98B | 25.6% | $311.52B |
| AZN | $58.74B | +8.6% | $10.22B | 17.4% | $289.61B |
| ABT | $48.23B | +10.0% | $4.70B | 9.7% | $191.31B |
| NVO | DKK 309.06B | +6.4% | DKK 102.43B | 33.1% | $180.22B |