HROW insider transactions

Large owner Opaleye Management Inc. sold $7,846,426 worth of shares (198,572 units at $39.51) (SEC Form 4)

Large owner Opaleye Management Inc. sold $270,900 worth of shares (5,000 units at $54.18) (SEC Form 4)

SEC Form 4 filed by CHIEF COMMERCIAL OFFICER Sullivan Patrick William

SEC Form 3 filed by new insider Sullivan Patrick William

Large owner Opaleye Management Inc. sold $1,066,914 worth of shares (20,000 units at $53.35) (SEC Form 4)

PRESIDENT AND CFO Boll Andrew R. exercised 60,000 shares at a strike of $3.95 and covered exercise/tax liability with 26,665 shares, increasing direct ownership by 4% to 811,179 units (SEC Form 4)

CHIEF EXECUTIVE OFFICER Baum Mark L exercised 180,000 shares at a strike of $3.95 and covered exercise/tax liability with 79,994 shares, increasing direct ownership by 3% to 2,986,130 units (SEC Form 4)

SEC Form 3 filed by new insider Mullery Francis William Jr

SEC Form 4 filed by CHIEF ACCOUNTING OFFICER Pollard Randall E.

SEC Form 3 filed by new insider Pollard Randall E.

CHIEF EXECUTIVE OFFICER Baum Mark L covered exercise/tax liability with 313,338 shares and exercised 600,000 shares at a strike of $7.87, increasing direct ownership by 11% to 2,886,124 units (SEC Form 4)

SEC Form 4 filed by CHIEF FINANCIAL OFFICER Boll Andrew R.

SEC Form 4 filed by CHIEF EXECUTIVE OFFICER Baum Mark L

SEC Form 4 filed by Director Sternberg Perry J.

SEC Form 4 filed by Director Silvernail Lauren P

SEC Form 4 filed by Director Graves Adrienne L

Large owner Opaleye Management Inc. sold $923,827 worth of shares (30,204 units at $30.59) (SEC Form 4)

Large owner Opaleye Management Inc. sold $144,024 worth of shares (4,796 units at $30.03) (SEC Form 4)

Large owner Opaleye Management Inc. sold $391,904 worth of shares (15,000 units at $26.13) (SEC Form 4)

Amendment: Large owner Opaleye Management Inc. sold $148,200 worth of shares (5,000 units at $29.64) (SEC Form 4)

Amendment: Large owner Opaleye Management Inc. sold $150,055 worth of shares (5,000 units at $30.01) (SEC Form 4)

Chief Financial Officer Boll Andrew R. converted options into 346,500 shares and covered exercise/tax liability with 136,745 shares, increasing direct ownership by 37% to 777,844 units (SEC Form 4)

CEO & President, ImprimisRx Saharek John P. covered exercise/tax liability with 109,475 shares and converted options into 277,200 shares, increasing direct ownership by 56% to 467,388 units (SEC Form 4)

Chief Executive Officer Baum Mark L covered exercise/tax liability with 300,363 shares and converted options into 762,300 shares, increasing direct ownership by 22% to 2,599,462 units (SEC Form 4)

Large owner Opaleye Management Inc. sold $150,055 worth of shares (5,000 units at $30.01) (SEC Form 4)

Large owner Opaleye Management Inc. sold $148,200 worth of shares (5,000 units at $29.64) (SEC Form 4)

Large owner Opaleye Management Inc. sold $140,250 worth of shares (5,000 units at $28.05) (SEC Form 4)

Large owner Opaleye Management Inc. sold $711,814 worth of shares (20,000 units at $35.59) (SEC Form 4)

SEC Form 4 filed by CHIEF SCIENTIFIC OFFICER Shojaei Amir

SEC Form 3 filed by new insider Shojaei Amir

CEO of ImprimisRx Saharek John P. exercised 90,000 shares at a strike of $7.37 and covered exercise/tax liability with 45,140 shares, increasing direct ownership by 18% to 299,663 units (SEC Form 4)

SEC Form 4 filed by Director Sternberg Perry J.

SEC Form 4 filed by Director Graves Adrienne L

SEC Form 4 filed by Director Silvernail Lauren P

SEC Form 4 filed by Director Makary Martin A.

Opaleye Management Inc. bought $199,400 worth of shares (20,000 units at $9.97) (SEC Form 4)

Opaleye Management Inc. bought $204,640 worth of shares (20,000 units at $10.23) (SEC Form 4)

Opaleye Management Inc. bought $310,390 worth of shares (29,400 units at $10.56) (SEC Form 4)

Opaleye Management Inc. bought $641,000 worth of shares (50,000 units at $12.82) (SEC Form 4)

Baum Mark L bought $104,310 worth of shares (9,000 units at $11.59), increasing direct ownership by 0.42% to 2,137,525 units (SEC Form 4)

Opaleye Management Inc. bought $488,290 worth of shares (50,600 units at $9.65) (SEC Form 4)

Saharek John P. exercised 5,000 shares at a strike of $8.75, increasing direct ownership by 2% to 254,803 units (SEC Form 4)

Saharek John P. exercised 30,000 shares at a strike of $10.67, increasing direct ownership by 7% to 249,803 units (SEC Form 4)

Boll Andrew R. exercised 45,000 shares at a strike of $10.67, increasing direct ownership by 5% to 568,089 units (SEC Form 4)

Baum Mark L exercised 150,000 shares at a strike of $10.67, increasing direct ownership by 4% to 2,128,525 units (SEC Form 4)

Baum Mark L exercised 15,400 shares at a strike of $7.71, increasing direct ownership by 0.76% to 2,038,361 units (SEC Form 4)

Boll Andrew R. exercised 7,400 shares at a strike of $7.71, increasing direct ownership by 1% to 541,569 units (SEC Form 4)

SEC Form 4 filed by Graves Adrienne L

SEC Form 4 filed by Silvernail Lauren P

SEC Form 3 filed by new insider Silvernail Lauren P

SEC Form 3 filed by new insider Graves Adrienne L

Baum Mark L bought $60,825 worth of shares (7,500 units at $8.11), increasing direct ownership by 0.37% to 2,022,961 units (SEC Form 4)

Opaleye Management Inc. bought $200,735 worth of shares (25,000 units at $8.03) (SEC Form 4)

Saharek John P. converted options into 20,000 shares and covered exercise/tax liability with 9,778 shares, increasing direct ownership by 5% to 232,419 units (SEC Form 4)

SEC Form 4: Opaleye Management Inc. bought $292,076 worth of shares (20,000 units at $14.60)

SEC Form 4: Makary Martin A. bought $338,400 worth of shares (20,000 units at $16.92), increasing direct ownership by 80% to 45,000 units

SEC Form 4: Baum Mark L bought $98,890 worth of shares (5,800 units at $17.05), increasing direct ownership by 0.29% to 2,015,461 units

SEC Form 4 filed by Baum Mark L

SEC Form 4 filed by Saharek John P.

SEC Form 4 filed by Boll Andrew R.