NUVL insider transactions

SEC Form 4 filed by Pelish Henry E.

SEC Form 4 filed by Porter James Richard

SEC Form 4 filed by Balcom Alexandra

SEC Form 4 filed by Lane Benjamin

SEC Form 4 filed by Noci Darlene

SEC Form 4 filed by Miller Deborah Ann

SEC Form 4 filed by Balcom Alexandra

SEC Form 3 filed by new insider Lane Benjamin

Chief Scientific Officer Pelish Henry E. exercised 17,320 shares at a strike of $31.52 and sold $3,442,856 worth of shares (35,104 units at $98.08), decreasing direct ownership by 21% to 65,604 units (SEC Form 4)

President and CEO Porter James Richard exercised 30,000 shares at a strike of $27.85 and sold $2,969,550 worth of shares (30,000 units at $98.99) (SEC Form 4)

Chief Development Officer Noci Darlene exercised 5,500 shares at a strike of $27.85 and sold $566,682 worth of shares (5,500 units at $103.03) (SEC Form 4)

Chief Legal Officer Miller Deborah Ann exercised 5,500 shares at a strike of $6.89 and sold $566,788 worth of shares (5,500 units at $103.05) (SEC Form 4)

Chief Development Officer Noci Darlene exercised 5,500 shares at a strike of $27.85 and sold $561,422 worth of shares (5,500 units at $102.08) (SEC Form 4)

Chief Legal Officer Miller Deborah Ann sold $1,652,176 worth of shares (15,000 units at $110.15) and exercised 15,000 shares at a strike of $27.85 (SEC Form 4)

Chief Scientific Officer Pelish Henry E. was granted 17,500 shares and sold $501,753 worth of shares (5,160 units at $97.24), increasing direct ownership by 17% to 83,388 units (SEC Form 4)

Chief Development Officer Noci Darlene sold $721,320 worth of shares (7,417 units at $97.25) and was granted 17,500 shares, increasing direct ownership by 21% to 58,117 units (SEC Form 4)

Chief Legal Officer Miller Deborah Ann sold $676,158 worth of shares (6,952 units at $97.26) and was granted 17,500 shares, increasing direct ownership by 21% to 59,634 units (SEC Form 4)

Chief Medical Officer Turner Christopher Durant sold $721,320 worth of shares (7,417 units at $97.25) and was granted 17,500 shares, increasing direct ownership by 16% to 72,630 units (SEC Form 4)

Chief Financial Officer Balcom Alexandra sold $721,320 worth of shares (7,417 units at $97.25) and was granted 17,500 shares, increasing direct ownership by 11% to 99,233 units (SEC Form 4)

President and CEO Porter James Richard was granted 46,250 shares and sold $2,668,260 worth of shares (27,433 units at $97.26), increasing direct ownership by 6% to 324,879 units (SEC Form 4)

Chief Legal Officer Miller Deborah Ann exercised 10,000 shares at a strike of $18.93 and sold $1,005,114 worth of shares (10,000 units at $100.51) (SEC Form 4)

Chief Development Officer Noci Darlene exercised 4,000 shares at a strike of $27.85 and sold $400,179 worth of shares (4,000 units at $100.04) (SEC Form 4)

Chief Scientific Officer Pelish Henry E. exercised 5,085 shares at a strike of $1.08, increasing direct ownership by 8% to 71,048 units (SEC Form 4)

Chief Financial Officer Balcom Alexandra exercised 34,500 shares at a strike of $1.08, increasing direct ownership by 63% to 89,150 units (SEC Form 4)

President and CEO Porter James Richard exercised 57,000 shares at a strike of $0.65, increasing direct ownership by 23% to 306,062 units (SEC Form 4)

Director Squarer Ron was granted 2,837 shares (SEC Form 4)

SEC Form 3 filed by new insider Squarer Ron

Chief Financial Officer Balcom Alexandra sold $781,537 worth of shares (7,084 units at $110.32), decreasing direct ownership by 11% to 54,650 units (SEC Form 4)

Chief Development Officer Noci Darlene exercised 4,000 shares at a strike of $27.85 and sold $434,319 worth of shares (4,000 units at $108.58) (SEC Form 4)

Director Shair Matthew sold $820,274 worth of shares (7,500 units at $109.37), decreasing direct ownership by 0.42% to 1,377,194 units (SEC Form 4)

Director by Deputization Flynn James E sold $70,874,975 worth of shares (742,574 units at $95.44) (SEC Form 4)

Chief Financial Officer Balcom Alexandra exercised 20,729 shares at a strike of $50.64 and sold $2,065,030 worth of shares (20,729 units at $99.62) (SEC Form 4)

Chief Legal Officer Miller Deborah Ann exercised 24,200 shares at a strike of $6.89 and sold $2,552,999 worth of shares (24,200 units at $105.50) (SEC Form 4)

Chief Development Officer Noci Darlene sold $411,661 worth of shares (4,000 units at $102.92) and exercised 4,000 shares at a strike of $27.85 (SEC Form 4)

Chief Legal Officer Miller Deborah Ann exercised 21,800 shares at a strike of $6.89 and sold $2,248,943 worth of shares (21,800 units at $103.16) (SEC Form 4)

Director Shair Matthew sold $6,015,464 worth of shares (60,000 units at $100.26), decreasing direct ownership by 3% to 1,383,044 units (SEC Form 4)

Chief Legal Officer Miller Deborah Ann exercised 5,000 shares at a strike of $6.89 and sold $474,550 worth of shares (5,000 units at $94.91) (SEC Form 4)

President and CEO Porter James Richard exercised 27,000 shares at a strike of $18.93 and sold $2,447,021 worth of shares (27,000 units at $90.63) (SEC Form 4)

Chief Legal Officer Miller Deborah Ann exercised 28,000 shares at a strike of $6.89 and sold $2,540,290 worth of shares (28,000 units at $90.72) (SEC Form 4)

Chief Scientific Officer Pelish Henry E. sold $1,279,018 worth of shares (14,205 units at $90.04) and exercised 14,205 shares at a strike of $35.08 (SEC Form 4)

Chief Financial Officer Balcom Alexandra exercised 1,683 shares at a strike of $18.93 and sold $144,014 worth of shares (1,683 units at $85.57) (SEC Form 4)

Chief Financial Officer Balcom Alexandra exercised 40,000 shares at a strike of $16.86 and sold $3,494,303 worth of shares (40,000 units at $87.36) (SEC Form 4)

Chief Scientific Officer Pelish Henry E. exercised 10,070 shares at a strike of $33.80 and sold $894,578 worth of shares (10,070 units at $88.84) (SEC Form 4)

Chief Financial Officer Balcom Alexandra exercised 20,000 shares at a strike of $8.82 and sold $1,709,512 worth of shares (20,000 units at $85.48) (SEC Form 4)

Chief Financial Officer Balcom Alexandra sold $2,346,256 worth of shares (27,588 units at $85.05) and exercised 27,588 shares at a strike of $6.89 (SEC Form 4)

Chief Development Officer Noci Darlene exercised 4,000 shares at a strike of $27.85 and sold $332,288 worth of shares (4,000 units at $83.07) (SEC Form 4)

President and CEO Porter James Richard exercised 27,000 shares at a strike of $18.93 and sold $2,135,055 worth of shares (27,000 units at $79.08) (SEC Form 4)

Chief Scientific Officer Pelish Henry E. exercised 3,725 shares at a strike of $26.94 and sold $293,642 worth of shares (3,725 units at $78.83) (SEC Form 4)

Chief Scientific Officer Pelish Henry E. exercised 5,007 shares at a strike of $1.00, increasing direct ownership by 8% to 65,963 units (SEC Form 4)

Chief Development Officer Noci Darlene exercised 4,000 shares at a strike of $27.85 and sold $298,489 worth of shares (4,000 units at $74.62) (SEC Form 4)

President and CEO Porter James Richard exercised 27,000 shares at a strike of $18.93 and sold $2,036,325 worth of shares (27,000 units at $75.42) (SEC Form 4)

Chief Scientific Officer Pelish Henry E. exercised 5,500 shares at a strike of $27.71 and sold $411,675 worth of shares (5,500 units at $74.85) (SEC Form 4)

Chief Development Officer Noci Darlene exercised 4,000 shares at a strike of $27.85 and sold $321,440 worth of shares (4,000 units at $80.36) (SEC Form 4)

Chief Financial Officer Balcom Alexandra exercised 20,000 shares at a strike of $18.93 and sold $1,693,496 worth of shares (20,000 units at $84.67) (SEC Form 4)

President and CEO Porter James Richard exercised 27,000 shares at a strike of $18.93 and sold $2,221,419 worth of shares (27,000 units at $82.27) (SEC Form 4)

Chief Scientific Officer Pelish Henry E. sold $613,986 worth of shares (7,645 units at $80.31) and exercised 5,500 shares at a strike of $28.75, decreasing direct ownership by 3% to 60,956 units (SEC Form 4)

Chief Financial Officer Balcom Alexandra exercised 20,000 shares at a strike of $18.93 and sold $1,600,400 worth of shares (20,000 units at $80.02) (SEC Form 4)

Chief Development Officer Noci Darlene exercised 4,000 shares at a strike of $27.85 and sold $314,826 worth of shares (4,000 units at $78.71) (SEC Form 4)

Chief Scientific Officer Pelish Henry E. exercised 10,800 shares at a strike of $28.78 and sold $862,705 worth of shares (10,800 units at $79.88) (SEC Form 4)

Director by Deputization Flynn James E was granted 5,294 shares (SEC Form 4)