QURE insider transactions

Chief Customer & Strat Officer O'Keefe Kylie was granted 19,800 units of Ordinary Shares, increasing direct ownership by 19% to 124,800 units (SEC Form 4)

New insider O'Keefe Kylie claimed ownership of 105,000 units of Ordinary Shares (SEC Form 3)

CEO, Managing Director Kapusta Matthew C was granted 70,600 units of Ordinary Shares and sold $132,104 worth of Ordinary Shares (14,581 units at $9.06), increasing direct ownership by 9% to 660,658 units (SEC Form 4)

Chief Medical Officer Abi-Saab Walid sold $7,320 worth of Ordinary Shares (808 units at $9.06) and was granted 41,700 units of Ordinary Shares, increasing direct ownership by 27% to 189,669 units (SEC Form 4)

Chief Legal Officer Potts Jeannette was granted 35,400 units of Ordinary Shares and sold $30,913 worth of Ordinary Shares (3,412 units at $9.06), increasing direct ownership by 30% to 138,483 units (SEC Form 4)

Chief Financial Officer Klemt Christian was granted 39,600 units of Ordinary Shares and sold $108,720 worth of Ordinary Shares (12,000 units at $9.06), increasing direct ownership by 14% to 226,581 units (SEC Form 4)

CEO, Managing Director Kapusta Matthew C sold $342,648 worth of Ordinary Shares (34,437 units at $9.95), decreasing direct ownership by 5% to 604,639 units (SEC Form 4)

Chief Financial Officer Klemt Christian sold $124,693 worth of Ordinary Shares (12,532 units at $9.95), decreasing direct ownership by 6% to 198,981 units (SEC Form 4)

Chief Legal Officer Potts Jeannette sold $85,351 worth of Ordinary Shares (8,578 units at $9.95), decreasing direct ownership by 7% to 106,495 units (SEC Form 4)

Chief Medical Officer Abi-Saab Walid sold $16,517 worth of Ordinary Shares (1,660 units at $9.95), decreasing direct ownership by 1% to 148,777 units (SEC Form 4)

CEO, Managing Director Kapusta Matthew C sold $295,339 worth of Ordinary Shares (12,378 units at $23.86), decreasing direct ownership by 2% to 639,076 units (SEC Form 4)

Chief Financial Officer Klemt Christian sold $148,338 worth of Ordinary Shares (6,217 units at $23.86), decreasing direct ownership by 3% to 211,513 units (SEC Form 4)

Director Gut Robert exercised 17,810 units of Ordinary Shares at a strike of $14.08 and sold $630,483 worth of Ordinary Shares (25,613 units at $24.62), decreasing direct ownership by 19% to 32,342 units (SEC Form 4)

Director Kaye Jack exercised 6,390 units of Ordinary Shares at a strike of $19.39 and sold $174,319 worth of Ordinary Shares (6,390 units at $27.28) (SEC Form 4)

Director Gut Robert exercised 15,840 units of Ordinary Shares at a strike of $4.57 and sold $856,881 worth of Ordinary Shares (31,434 units at $27.26), decreasing direct ownership by 28% to 40,145 units (SEC Form 4)

Director Kaye Jack sold $1,177,517 worth of Ordinary Shares (38,810 units at $30.34) and exercised 38,810 units of Ordinary Shares at a strike of $9.88 (SEC Form 4)

CEO, Managing Director Kapusta Matthew C exercised 226,316 units of Ordinary Shares at a strike of $6.52 and sold $9,382,473 worth of Ordinary Shares (226,316 units at $41.46) (SEC Form 4)

Chief Financial Officer Klemt Christian exercised 18,000 units of Ordinary Shares at a strike of $6.65 and sold $945,120 worth of Ordinary Shares (18,000 units at $52.51) (SEC Form 4)

Chief Medical Officer Abi-Saab Walid sold $20,407 worth of Ordinary Shares (1,466 units at $13.92), decreasing direct ownership by 0.97% to 150,437 units (SEC Form 4)

Director Springhorn Jeremy P. sold $30,518 worth of Ordinary Shares (2,112 units at $14.45), decreasing direct ownership by 5% to 37,694 units (SEC Form 4)

Director Post Leonard E sold $30,518 worth of Ordinary Shares (2,112 units at $14.45), decreasing direct ownership by 7% to 29,937 units (SEC Form 4)

Director Kaye Jack sold $30,518 worth of Ordinary Shares (2,112 units at $14.45), decreasing direct ownership by 9% to 20,439 units (SEC Form 4)

Director Jacques Rachelle Suzanne sold $30,518 worth of Ordinary Shares (2,112 units at $14.45), decreasing direct ownership by 7% to 28,346 units (SEC Form 4)

Director Gut Robert sold $48,205 worth of Ordinary Shares (3,336 units at $14.45), decreasing direct ownership by 6% to 56,879 units (SEC Form 4)

Director Balachandran Madhavan sold $30,518 worth of Ordinary Shares (2,112 units at $14.45), decreasing direct ownership by 5% to 37,697 units (SEC Form 4)

Director Meek David D. sold $30,518 worth of Ordinary Shares (2,112 units at $14.45), decreasing direct ownership by 6% to 34,190 units (SEC Form 4)

Chief Legal Officer Potts Jeannette sold $70,704 worth of Ordinary Shares (4,670 units at $15.14), decreasing direct ownership by 4% to 115,073 units (SEC Form 4)

Director Post Leonard E was granted 7,970 units of Ordinary Shares, increasing direct ownership by 33% to 32,049 units (SEC Form 4)

Director Kaye Jack was granted 7,970 units of Ordinary Shares, increasing direct ownership by 55% to 22,551 units (SEC Form 4)

Director Jacques Rachelle Suzanne was granted 7,970 units of Ordinary Shares, increasing direct ownership by 35% to 30,458 units (SEC Form 4)

Director Gut Robert was granted 7,970 units of Ordinary Shares, increasing direct ownership by 15% to 60,215 units (SEC Form 4)

Director Balachandran Madhavan was granted 7,970 units of Ordinary Shares, increasing direct ownership by 25% to 39,809 units (SEC Form 4)

Director Springhorn Jeremy P. was granted 7,970 units of Ordinary Shares, increasing direct ownership by 25% to 39,806 units (SEC Form 4)

Director Meek David D. was granted 7,970 units of Ordinary Shares, increasing direct ownership by 28% to 36,302 units (SEC Form 4)

CEO, Managing Director Kapusta Matthew C was granted 99,000 units of Ordinary Shares and sold $291,629 worth of Ordinary Shares (28,341 units at $10.29), increasing direct ownership by 12% to 651,454 units (SEC Form 4)

Chief Medical Officer Abi-Saab Walid was granted 38,000 units of Ordinary Shares and sold $13,891 worth of Ordinary Shares (1,350 units at $10.29), increasing direct ownership by 32% to 151,903 units (SEC Form 4)

Chief Financial Officer Klemt Christian was granted 73,000 units of Ordinary Shares and sold $107,407 worth of Ordinary Shares (10,438 units at $10.29), increasing direct ownership by 40% to 217,730 units (SEC Form 4)

Chief Legal Officer Potts Jeannette was granted 35,000 units of Ordinary Shares and sold $72,812 worth of Ordinary Shares (7,076 units at $10.29), increasing direct ownership by 30% to 119,743 units (SEC Form 4)

CEO, Managing Director Kapusta Matthew C sold $362,015 worth of Ordinary Shares (33,444 units at $10.82) and was granted 16,324 units of Ordinary Shares, decreasing direct ownership by 3% to 580,795 units (SEC Form 4)

Chief Financial Officer Klemt Christian sold $186,458 worth of Ordinary Shares (17,257 units at $10.80) and was granted 5,712 units of Ordinary Shares, decreasing direct ownership by 7% to 155,168 units (SEC Form 4)

CEO, Managing Director Kapusta Matthew C exercised 100,000 units of Ordinary Shares at a strike of $14.71 and sold $1,503,000 worth of Ordinary Shares (100,000 units at $15.03) (SEC Form 4)

CEO, Managing Director Kapusta Matthew C was granted 10,494 units of Ordinary Shares and sold $26,079 worth of Ordinary Shares (3,418 units at $7.63), increasing direct ownership by 1% to 597,915 units (SEC Form 4)

Chief Financial Officer Klemt Christian was granted 3,672 units of Ordinary Shares and sold $13,560 worth of Ordinary Shares (1,796 units at $7.55), increasing direct ownership by 1% to 166,713 units (SEC Form 4)

Chief Medical Officer Abi-Saab Walid sold $6,309 worth of Ordinary Shares (1,447 units at $4.36), decreasing direct ownership by 1% to 115,253 units (SEC Form 4)

Director Gut Robert was granted 8,080 units of Ordinary Shares, increasing direct ownership by 18% to 52,245 units (SEC Form 4)

Director Springhorn Jeremy P. was granted 8,080 units of Ordinary Shares, increasing direct ownership by 34% to 31,836 units (SEC Form 4)

Director Meek David D. was granted 8,080 units of Ordinary Shares, increasing direct ownership by 40% to 28,332 units (SEC Form 4)

Director Balachandran Madhavan was granted 8,080 units of Ordinary Shares, increasing direct ownership by 34% to 31,839 units (SEC Form 4)

Director Kaye Jack was granted 8,080 units of Ordinary Shares, increasing direct ownership by 124% to 14,581 units (SEC Form 4)

Director Post Leonard E was granted 8,080 units of Ordinary Shares, increasing direct ownership by 51% to 24,079 units (SEC Form 4)

Director Jacques Rachelle Suzanne was granted 8,080 units of Ordinary Shares, increasing direct ownership by 56% to 22,488 units (SEC Form 4)

Chief Operating Officer Caloz Pierre sold $14,122 worth of Ordinary Shares (2,936 units at $4.81), decreasing direct ownership by 2% to 115,707 units (SEC Form 4)

Chief Financial Officer Klemt Christian sold $7,733 worth of Ordinary Shares (1,611 units at $4.80), decreasing direct ownership by 0.97% to 164,837 units (SEC Form 4)

Director Post Leonard E sold $11,421 worth of Ordinary Shares (2,222 units at $5.14), decreasing direct ownership by 12% to 15,999 units (SEC Form 4)

Chief Legal Officer Potts Jeannette sold $23,809 worth of Ordinary Shares (4,781 units at $4.98), decreasing direct ownership by 5% to 91,819 units (SEC Form 4)

Director Springhorn Jeremy P. sold $11,423 worth of Ordinary Shares (2,231 units at $5.12), decreasing direct ownership by 9% to 23,756 units (SEC Form 4)

Director Meek David D. sold $11,412 worth of Ordinary Shares (2,229 units at $5.12), decreasing direct ownership by 10% to 20,252 units (SEC Form 4)

Director Balachandran Madhavan sold $11,423 worth of Ordinary Shares (2,231 units at $5.12), decreasing direct ownership by 9% to 23,759 units (SEC Form 4)

Director Soteropoulos Paula sold $11,411 worth of Ordinary Shares (2,220 units at $5.14), decreasing direct ownership by 10% to 20,203 units (SEC Form 4)

Director Gut Robert sold $17,940 worth of Ordinary Shares (3,504 units at $5.12), decreasing direct ownership by 7% to 44,165 units (SEC Form 4)