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Ionis partner Roche announces new Phase 3 data showing sefaxersen significantly reduced proteinuria in people with IgA nephropathy (IgAN)

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Historical context for IONS

Across the 26 sessions after earlier IONS headlines, the stock closed higher 10 times and lower 16 times, with a median move of 2.1% in either direction. This shows timing only: many things move a stock in a session, and these figures do not show that any headline caused a move.

IONS close-to-close change in the session after earlier headlines
SessionEarlier headlineIONSSPY
Oct 22, 2026Ionis ranked #1 on Science’s Top Employers listand 1 other headline that session-0.8%-1.2%
Oct 21, 2026Ionis partner GSK announces Hibsago (bepirovirsen) approved in the U.S. for the treatment of chronic hepatitis B (CHB)-2.5%+0.5%
Oct 16, 2026TRYNGOLZA® (olezarsen) recommended for approval in the EU by CHMP for severe hypertriglyceridemia (sHTG)-2.7%-1.1%
Oct 15, 2026UBS resumed coverage on Ionis Pharma with a new price target+3.3%+0.3%
Sep 23, 2026Ionis announces positive interim data from partner Roche’s Phase 3 IMAgINATION study in IgA nephropathy (IgAN)-4.0%-0.7%
Sep 22, 2026Ionis announces positive topline results from Phase 3 FUSION study of ulefnersen marking significant milestone in advancing first potential disease modifying treatment for FUS-ALS+1.9%-0.0%

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Ionis Pharmaceuticals Inc. logo
IONS
Ionis Pharmaceuticals Inc.
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30-day
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Health Care
Industry
Biotechnology: Pharmaceutical Preparations
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