Rankings · YTD gainers
Best-performing stocks of 2026 so far: Health Care
Every liquid US stock with a gain over the year to date, ranked from largest gain down, with sector and market cap filters. Updated after each close.
Prices as of Nov 3, 2026 · 334 stocks · data, not a recommendation
| # | Stock | Sector | YTD | Price | 1M | 1Y | Market cap |
|---|---|---|---|---|---|---|---|
| 1 | MRNAModerna Inc. | Health Care | +674.6% | $228.44 | +12.4% | +741.1% | $88.16B |
| 2 | ANLAdlai Nortye Group Ltd. | Health Care | +574.6% | $9.58 | -36.3% | +569.9% | $603.4M |
| 3 | AGLagilon health inc. | Health Care | +409.8% | $87.79 | +4.2% | +340.9% | $1.45B |
| 4 | CDNACareDx Inc. | Health Care | +369.6% | $88.47 | +26.7% | +489.8% | $4.51B |
| 5 | RCELAvita Medical Inc. | Health Care | +344.3% | $15.33 | +15.7% | +296.1% | $476.6M |
| 6 | TWSTTwist Bioscience Corporation | Health Care | +342.3% | $140.30 | -31.6% | +326.6% | $8.56B |
| 7 | IBRXImmunityBio Inc. | Health Care | +318.7% | $8.29 | -20.1% | +245.4% | $8.43B |
| 8 | ERASErasca Inc. | Health Care | +293.5% | $14.64 | -0.5% | +505.0% | $4.91B |
| 9 | PLSEPulse Biosciences Inc | Health Care | +280.2% | $52.20 | +3.4% | +208.3% | $3.77B |
| 10 | ANTXAN2 Therapeutics Inc. | Health Care | +266.7% | $4.18 | -25.5% | +239.8% | $164.2M |
| 11 | KRSAKorsana Biosciences Inc. | Health Care | +259.5% | $31.96 | +4.0% | +144.2% | $1.44B |
| 12 | ABCLAbCellera Biologics Inc. | Health Care | +256.1% | $12.18 | -11.6% | +119.5% | $3.60B |
| 13 | KODKodiak Sciences Inc | Health Care | +253.7% | $98.89 | +5.4% | +445.6% | $6.14B |
| 14 | ORKAOruka Therapeutics Inc. | Health Care | +228.4% | $99.55 | +18.0% | +253.4% | $6.32B |
| 15 | SLNSilence Therapeutics Plc | Health Care | +225.3% | $19.78 | +95.1% | +176.3% | $1.23B |
| 16 | IOVAIovance Biotherapeutics Inc. | Health Care | +223.4% | $8.83 | -37.6% | +348.2% | $3.63B |
| 17 | SYRESpyre Therapeutics Inc. | Health Care | +203.0% | $99.27 | +7.1% | +305.8% | $9.97B |
| 18 | ETONEton Pharmaceuticals Inc. | Health Care | +201.3% | $50.95 | -8.4% | +182.9% | $1.45B |
| 19 | ELVNEnliven Therapeutics Inc. | Health Care | +191.1% | $44.83 | -1.4% | +91.4% | $3.27B |
| 20 | ABSIAbsci Corporation | Health Care | +186.5% | $10.00 | -13.3% | +133.6% | $1.66B |
| 21 | OABIOmniAb Inc. | Health Care | +178.4% | $5.15 | +4.7% | +232.3% | $742.4M |
| 22 | DRTSAlpha Tau Medical Ltd. | Health Care | +173.5% | $13.54 | -9.1% | +225.1% | $1.19B |
| 23 | QTTBQ32 Bio Inc. | Health Care | +163.9% | $8.76 | +4.7% | +211.7% | $259.3M |
| 24 | TNGXTango Therapeutics Inc. | Health Care | +161.5% | $23.17 | +0.4% | +185.7% | $3.67B |
| 25 | NVCTNuvectis Pharma Inc. | Health Care | +156.2% | $19.34 | -9.6% | +188.2% | $625.5M |
| 26 | DFTXDefinium Therapeutics Inc. | Health Care | +149.5% | $33.41 | -7.8% | +135.3% | $4.36B |
| 27 | RVMDRevolution Medicines Inc. | Health Care | +143.9% | $194.23 | -6.5% | +230.1% | $40.33B |
| 28 | CLYMClimb Bio Inc. | Health Care | +143.8% | $9.75 | -11.8% | +375.6% | $559.4M |
| 29 | AMLXAmylyx Pharmaceuticals Inc. | Health Care | +141.7% | $29.20 | +5.1% | +109.6% | $3.52B |
| 30 | CORTCorcept Therapeutics Incorporated | Health Care | +135.4% | $81.93 | -32.9% | +11.5% | $8.70B |
| 31 | SLSSELLAS Life Sciences Group Inc. | Health Care | +135.3% | $8.87 | -23.7% | +387.4% | $1.73B |
| 32 | MRVIMaravai LifeSciences Holdings Inc. | Health Care | +129.2% | $7.45 | -12.6% | +137.3% | $1.87B |
| 33 | CUECue Biopharma Inc. | Health Care | +127.7% | $20.86 | -14.4% | -9.4% | $141.1M |
| 34 | KNSAKiniksa Pharmaceuticals International plc | Health Care | +126.2% | $93.29 | +22.3% | +152.1% | $7.13B |
| 35 | OSCROscar Health Inc. | Health Care | +125.5% | $32.41 | -0.0% | +80.1% | $9.57B |
| 36 | CYPHCypherpunk Technologies Inc. | Health Care | +124.1% | $2.60 | -18.0% | +481.4% | $254.3M |
| 37 | HURATuHURA Biosciences Inc. | Health Care | +118.7% | $1.66 | -11.5% | -35.1% | $109.6M |
| 38 | REPLReplimune Group Inc. | Health Care | +112.4% | $20.65 | +57.0% | +112.2% | $1.85B |
| 39 | AGENAgenus Inc. | Health Care | +112.4% | $6.67 | -23.6% | +68.0% | $294.9M |
| 40 | ACHCAcadia Healthcare Company Inc. | Health Care | +108.7% | $29.62 | +2.6% | +37.8% | $2.76B |
| 41 | FATEFate Therapeutics Inc. | Health Care | +107.6% | $2.04 | -16.0% | +51.1% | $240.8M |
| 42 | GKOSGlaukos Corporation | Health Care | +106.4% | $233.04 | +42.1% | +164.6% | $14.12B |
| 43 | RLAYRelay Therapeutics Inc. | Health Care | +106.1% | $17.44 | -10.1% | +144.3% | $3.79B |
| 44 | CONConcentra Group Holdings Parent Inc. | Health Care | +104.0% | $40.15 | +10.9% | +101.6% | $5.14B |
| 45 | TGTXTG Therapeutics Inc. | Health Care | +103.8% | $60.75 | +12.7% | +74.7% | $9.18B |
| 46 | ANIKAnika Therapeutics Inc. | Health Care | +102.4% | $19.45 | -1.4% | +99.5% | $259.8M |
| 47 | DNTHDianthus Therapeutics Inc. | Health Care | +100.7% | $82.70 | -6.1% | +136.4% | $4.60B |
| 48 | XNCRXencor Inc. | Health Care | +100.1% | $30.64 | +19.5% | +108.3% | $2.21B |
| 49 | AZNAstraZeneca PLC | Health Care | +100.0% | $183.88 | +17.5% | +123.2% | $289.33B |
| 50 | BOLDBoundless Bio Inc. | Health Care | +98.3% | $2.38 | -8.5% | +70.0% | $56.4M |
| 51 | KRROKorro Bio Inc. | Health Care | +98.0% | $15.86 | +59.1% | -61.2% | $233.3M |
| 52 | PSNLPersonalis Inc. | Health Care | +97.9% | $15.75 | -4.0% | +63.4% | $1.68B |
| 53 | IRDOpus Genetics Inc. | Health Care | +95.5% | $3.93 | -10.3% | +70.9% | $307.8M |
| 54 | OGNOrganon & Co. | Health Care | +93.2% | $13.85 | +1.1% | +105.2% | $3.63B |
| 55 | TKNOAlpha Teknova Inc. | Health Care | +93.2% | $7.34 | -18.4% | +39.8% | $432.5M |
| 56 | HALOHalozyme Therapeutics Inc. | Health Care | +91.1% | $128.62 | +18.8% | +97.3% | $14.64B |
| 57 | LFSTLifeStance Health Group Inc. | Health Care | +89.9% | $13.37 | +9.4% | +172.9% | $5.07B |
| 58 | HTFLHeartflow Inc. | Health Care | +86.6% | $54.40 | +4.2% | +46.4% | $4.74B |
| 59 | BTSGBrightSpring Health Services Inc. | Health Care | +86.5% | $69.84 | +12.6% | +111.3% | $13.18B |
| 60 | VIRVir Biotechnology Inc. | Health Care | +86.1% | $11.22 | -4.8% | +88.3% | $1.88B |
| 61 | FTHFaeth Therapeutics Inc. | Health Care | +84.2% | $19.65 | -27.5% | +114.3% | $496.9M |
| 62 | PDSBPDS Biotechnology Corporation | Health Care | +83.2% | $1.41 | +17.5% | +50.8% | $143.9M |
| 63 | CLOVClover Health Investments Corp. | Health Care | +82.6% | $4.29 | -8.3% | +21.5% | $2.29B |
| 64 | ILMNIllumina Inc. | Health Care | +81.6% | $238.21 | -18.9% | +92.8% | $34.26B |
| 65 | LBRXLB Pharmaceuticals Inc | Health Care | +81.2% | $40.33 | +16.5% | +150.0% | $1.26B |
| 66 | GMABGenmab A/S | Health Care | +80.3% | $55.52 | +44.3% | +94.1% | $34.27B |
| 67 | STLNStarling Oncology Inc. | Health Care | +78.1% | $6.34 | +0.6% | +42.2% | $637.0M |
| 68 | KIDSOrthoPediatrics Corp. | Health Care | +76.9% | $31.41 | +37.2% | +86.5% | $794.5M |
| 69 | CRLCharles River Laboratories International Inc. | Health Care | +76.4% | $351.87 | +13.2% | +95.4% | $16.16B |
| 70 | TMCITreace Medical Concepts Inc. | Health Care | +74.7% | $4.28 | -4.5% | -33.0% | $277.7M |
| 71 | MBXMBX Biosciences Inc. | Health Care | +74.4% | $55.00 | -6.0% | +150.5% | $2.62B |
| 72 | ELDNEledon Pharmaceuticals Inc. | Health Care | +73.5% | $2.62 | +4.8% | -39.4% | $212.9M |
| 73 | NEOGNeogen Corporation | Health Care | +73.1% | $12.10 | -7.0% | +96.1% | $2.58B |
| 74 | RPRXRoyalty Pharma plc | Health Care | +71.8% | $66.40 | +17.2% | +76.9% | $38.25B |
| 75 | PBYIPuma Biotechnology Inc | Health Care | +71.8% | $10.22 | +5.7% | +100.4% | $525.5M |
| 76 | CYRXCryoPort Inc. | Health Care | +71.4% | $16.45 | -9.3% | +78.0% | $822.0M |
| 77 | GHGuardant Health Inc. | Health Care | +71.3% | $175.00 | -6.5% | +88.1% | $22.91B |
| 78 | INNVInnovAge Holding Corp. | Health Care | +70.5% | $8.85 | -1.7% | +97.1% | $1.22B |
| 79 | RZLTRezolute Inc. | Health Care | +69.9% | $4.01 | -7.4% | -57.0% | $375.3M |
| 80 | NTRANatera Inc. | Health Care | +69.6% | $388.63 | -8.7% | +95.4% | $54.62B |
| 81 | HOWLWerewolf Therapeutics Inc. | Health Care | +68.9% | $1.07 | +15.1% | -18.3% | $51.0M |
| 82 | BFLYButterfly Network Inc. | Health Care | +68.4% | $6.40 | -31.8% | +137.9% | $1.64B |
| 83 | SGMTSagimet Biosciences Inc. | Health Care | +68.1% | $9.95 | +10.2% | +16.8% | $683.5M |
| 84 | CCCCC4 Therapeutics Inc. | Health Care | +68.1% | $3.21 | +7.4% | +23.0% | $394.9M |
| 85 | DTILPrecision BioSciences Inc. | Health Care | +67.5% | $6.97 | +10.5% | -14.6% | $191.8M |
| 86 | ROIVRoivant Sciences Ltd. | Health Care | +66.1% | $36.04 | +0.7% | +80.3% | $25.92B |
| 87 | LGNDLigand Pharmaceuticals Incorporated | Health Care | +65.8% | $313.52 | +2.2% | +63.9% | $6.14B |
| 88 | EXELExelixis Inc. | Health Care | +65.0% | $72.31 | +22.9% | +87.0% | $17.11B |
| 89 | CNCCentene Corporation | Health Care | +64.0% | $67.48 | +4.9% | +90.8% | $32.94B |
| 90 | STIMNeuronetics Inc. | Health Care | +63.8% | $2.26 | +2.7% | -14.7% | $157.0M |
| 91 | KYMRKymera Therapeutics Inc. | Health Care | +63.3% | $127.09 | +15.7% | +105.5% | $10.89B |
| 92 | ALKSAlkermes plc | Health Care | +63.3% | $45.69 | +6.9% | +48.8% | $7.53B |
| 93 | HUMHumana Inc. | Health Care | +63.1% | $417.87 | +3.4% | +50.2% | $49.28B |
| 94 | GRALGRAIL Inc. | Health Care | +62.9% | $139.44 | -9.5% | +51.7% | $5.97B |
| 95 | AVAHAveanna Healthcare Holdings Inc. | Health Care | +62.5% | $13.28 | +7.4% | +46.7% | $2.86B |
| 96 | ITGRInteger Holdings Corporation | Health Care | +61.4% | $126.55 | +0.1% | +96.0% | $4.30B |
| 97 | PTGXProtagonist Therapeutics Inc. | Health Care | +60.6% | $140.24 | -0.3% | +78.4% | $9.02B |
| 98 | SENSSenseonics Holdings Inc. | Health Care | +60.5% | $8.86 | -14.1% | +25.7% | $474.8M |
| 99 | AMRXAmneal Pharmaceuticals Inc. | Health Care | +60.4% | $20.21 | -0.7% | +86.8% | $7.12B |
| 100 | IFRXInflaRx N.V. | Health Care | +60.4% | $1.62 | -3.6% | +11.0% | $260.1M |
How this ranking works
- How is the return calculated?
- It is the percent change in closing price over the window, from daily bars adjusted for splits and spin-offs across all US exchanges. Dividends are not added back.
- Which stocks are ranked?
- US-listed stocks that closed at $1 or higher, averaged at least 100,000 shares a day over 20 sessions and have a known market cap. ETFs are left out.
- Does a high rank mean a stock is a good investment?
- No. This list shows past price moves only. It says nothing about what a stock will do next.