Who owns GPCR?
Institutional ownership of Structure Therapeutics Inc. from Form 13F, Q2 2026
192 institutional managers reported holding Structure Therapeutics Inc. (GPCR) in Form 13F filings for Q2 2026, with 67,596,599 shares worth $3.6B. The largest reported holder was FMR LLC. Managers that filed both quarters added a net 782,812 shares (+1.3%). 28 opened new positions and 30 sold out.
- Funds holding
- 192
- Value held
- $3.6B
- New / sold out
- 28 / 30
- Net shares, same filers
- +1.3%
Holdings as of June 30, 2026, the end of Q2 2026. Managers have 45 days after a quarter ends to file Form 13F (by August 14, 2026 for Q2 2026), so positions may have changed since.
Largest holders of GPCR
| Fund | Value | Share of 13F holdings | Shares | Move |
|---|---|---|---|---|
| FMR LLC | $419M | 11.6% | 7,810,306 | Trimmed |
| Wellington Management Group LLP | $396M | 10.9% | 7,379,433 | Added |
| Avoro Capital Advisors LLC | $352M | 9.7% | 6,555,555 | Unchanged |
| Jupiter Topco LLC | $279M | 7.7% | 5,204,212 | First report |
| Deep Track Capital, LP | $254M | 7.0% | 4,740,072 | Added |
| BVF Inc | $181M | 5.0% | 3,366,823 | Trimmed |
| Morgan Stanley | $151M | 4.2% | 2,806,640 | Added |
| Orbimed Advisors LLC | $119M | 3.3% | 2,209,400 | Added |
| Principal Financial Group Inc | $94.1M | 2.6% | 1,752,753 | Unchanged |
| American Century Companies Inc | $90.3M | 2.5% | 1,682,179 | Added |
| RTW Investments, LP | $86.3M | 2.4% | 1,607,507 | New |
| Driehaus Capital Management LLC | $83.4M | 2.3% | 1,553,219 | Trimmed |
| Baker Bros. Advisors LP | $76.9M | 2.1% | 1,432,529 | Unchanged |
| Casdin Capital, LLC | $63.1M | 1.7% | 1,175,000 | Unchanged |
| Deerfield Management Company, L.p. | $58.3M | 1.6% | 1,086,000 | Added |
| Capitolis Liquid Global Markets LLC | $55.9M | 1.5% | 1,041,100 | Trimmed |
| Siren, L.L.C. | $46.9M | 1.3% | 872,967 | Trimmed |
| Price T Rowe Associates Inc | $45.4M | 1.3% | 845,532 | Trimmed |
| Pacific Heights Asset Management LLC | $42.9M | 1.2% | 800,000 | Added |
| Rock Springs Capital Management LP | $34.4M | 0.9% | 640,317 | Unchanged |
| Aberdeen Group plc | $34.3M | 0.9% | 639,915 | Added |
| Franklin Resources Inc | $31.1M | 0.9% | 578,839 | Added |
| Bank of America Corp | $30.2M | 0.8% | 563,422 | Added |
| Alliancebernstein L.p. | $29.5M | 0.9% | 611,708 | Trimmed |
| BlackRock, Inc. | $27.4M | 0.8% | 511,149 | Added |
Share of 13F holdings is each fund's shares as a share of the 67,596,599 GPCR shares all 13F filers reported, not of shares outstanding.
Biggest buyers in Q2 2026
- RTW Investments, LP New+$86.3M
- Orbimed Advisors LLC Added+$39.4M
- Morgan Stanley Added+$26.9M
- Deep Track Capital, LP Added+$24.7M
- Bank of America Corp Added+$18.0M
- Davern Capital Partners, LP Added+$17.2M
- Deerfield Management Company, L.p. Added+$17.1M
- Parkman Healthcare Partners LLC Added+$13.6M
- Aberdeen Group plc Added+$13.3M
- American Century Companies Inc Added+$13.1M
Biggest sellers in Q2 2026
- Price T Rowe Associates Inc Trimmed-$62.0M
- FMR LLC Trimmed-$31.8M
- Paradigm Biocapital Advisors LP Sold out-$26.3M
- Siren, L.L.C. Trimmed-$24.5M
- Stempoint Capital LP Trimmed-$19.4M
- Balyasny Asset Management L.P. Sold out-$14.7M
- Pentwater Capital Management LP Sold out-$11.8M
- JPMorgan Chase & Co Trimmed-$10.8M
- Sio Capital Management, LLC Sold out-$10.1M
- Holocene Advisors, LP Sold out-$7.7M
The change in shares since the quarter before, adjusted for stock splits and priced at the Q2 2026 value per share. Funds bought $382M and sold $329M; 75 added and 50 trimmed.
Schedule 13D and 13G filings on GPCR
Owners of more than 5% must file within days, so these can be newer than the 13F data.
- 2025-11-14Avoro Capital Advisors LLC SCHEDULE 13G filed by Structure Therapeutics Inc.Schedule 13G
- 2025-08-18BIOTECHNOLOGY VALUE FUND L P SCHEDULE 13G filed by Structure Therapeutics Inc.Schedule 13G
- 2025-01-13Deep Track Capital, LP SCHEDULE 13G filed by Structure Therapeutics Inc.Schedule 13G
Questions about GPCR ownership
- Who owns GPCR stock?
- 192 institutional investment managers reported GPCR positions in their Form 13F filings for Q2 2026, holding 67,596,599 shares worth $3.6B in total. FMR LLC reported the largest position.
- Are funds buying or selling GPCR?
- In Q2 2026, 28 managers opened new GPCR positions, 75 added, 50 trimmed and 30 sold out. Managers that filed in both quarters added a net 782,812 shares.
- How current is this GPCR institutional ownership data?
- It covers holdings as of the end of Q2 2026. Managers have 45 days after the quarter ends to file Form 13F (by August 14, 2026 for Q2 2026), so positions may have changed since.
From the SEC's Form 13F data sets for Q2 2026: every 13F holdings report, matched to GPCR by CUSIP. Options are left out. GPCR news and filings · GPCR insider trades · Top funds